| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Ice Age: Dawn of the Dinosaurs | $436,158 | -53.5% | 93 | +2 | $4,689 | $1,794,473 | 2 | NuMetro Distribution | false | false |
| 2 | - | The Proposal | $383,030 | - | 65 | - | $5,892 | $383,030 | 1 | Ster-Kinekor Pictures | true | false |
| 3 | 2 | Transformers: Revenge of the Fallen | $186,760 | -36.4% | 96 | -1 | $1,945 | $1,694,863 | 3 | United International Pictures | false | false |
| 4 | 4 | The Hangover | $118,288 | -15.8% | 56 | +1 | $2,112 | $1,002,744 | 4 | NuMetro Distribution | false | false |
| 5 | 3 | Knowing | $113,045 | -41.3% | 73 | - | $1,548 | $425,839 | 2 | United International Pictures | false | false |
| 6 | - | Brüno | $94,340 | - | 43 | - | $2,193 | $94,340 | 1 | United International Pictures | true | false |
| 7 | 5 | Night at the Museum: Battle of the Smithsonian | $40,730 | -42.6% | 60 | -18 | $678 | $1,531,579 | 8 | NuMetro Distribution | false | false |
| 8 | 7 | Obsessed | $23,114 | -32.6% | 21 | -3 | $1,100 | $215,219 | 4 | Ster-Kinekor Pictures | false | false |
| 9 | 6 | Ghosts of Girlfriends Past | $20,246 | -47.5% | 35 | -7 | $578 | $958,015 | 9 | NuMetro Distribution | false | false |
| 10 | 8 | Kambakkht Ishq | $19,774 | -31.7% | 6 | - | $3,295 | $62,969 | 2 | NuMetro Distribution | false | false |
| 11 | 11 | Duplicity | $14,490 | -35.6% | 23 | -11 | $630 | $598,368 | 7 | United International Pictures | false | false |
| 12 | - | The Young Victoria | $12,160 | - | 10 | - | $1,216 | $68,280 | 3 | NuMetro Distribution | false | false |
| 13 | 10 | Drag Me to Hell | $11,239 | -51.4% | 22 | -8 | $510 | $309,075 | 5 | NuMetro Distribution | false | false |
| 14 | 12 | State of Play | $10,443 | -53.4% | 16 | -7 | $652 | $295,908 | 5 | United International Pictures | false | false |
| 15 | 14 | The Brothers Bloom | $9,118 | -22.1% | 10 | - | $911 | $28,981 | 2 | Ster-Kinekor Pictures | false | false |
| 16 | 16 | Welcome to the Sticks | $5,779 | -8.4% | 4 | - | $1,444 | $27,887 | 3 | Ster-Kinekor Pictures | false | false |
| 17 | - | The Song of Sparrows | $5,324 | - | 3 | - | $1,774 | $5,324 | 1 | Ster-Kinekor Pictures | true | false |
| 18 | 9 | Terminator Salvation | $5,137 | -80.2% | 18 | -35 | $285 | $824,302 | 6 | Ster-Kinekor Pictures | false | false |
| 19 | 17 | Sunshine Cleaning | $4,047 | -29% | 8 | -2 | $505 | $74,562 | 5 | United International Pictures | false | false |
| 20 | - | Shortkut - The Con Is On | $3,879 | - | 5 | - | $775 | $3,879 | 1 | Ster-Kinekor Pictures | true | false |
| 21 | - | The Burning Plain | $3,508 | - | 6 | - | $584 | $75,722 | 6 | United International Pictures | false | false |
| 22 | - | uMalusi | $3,202 | - | 14 | - | $228 | $3,202 | 1 | Ster-Kinekor Pictures | true | false |
| 23 | - | The Last House on the Left | $978 | - | 3 | - | $326 | $124,823 | 8 | United International Pictures | false | false |
