| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Ice Age: Dawn of the Dinosaurs | $1,599,339 | - | 133 | - | $12,025 | $1,599,339 | 1 | 20th Century Fox International | true | false |
| 2 | 1 | Transformers: Revenge of the Fallen | $451,187 | -54.8% | 92 | - | $4,904 | $1,653,864 | 2 | Universal Pictures International (UPI) | false | false |
| 3 | 2 | The Proposal | $180,907 | -36% | 47 | +1 | $3,849 | $1,243,408 | 3 | Walt Disney Pictures | false | false |
| 4 | 3 | The Hangover | $138,562 | -29% | 40 | -5 | $3,464 | $953,181 | 3 | Warner Bros. | false | false |
| 5 | - | Het geheim van Mega Mindy | $100,302 | - | 33 | - | $3,039 | $128,246 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 6 | - | Ghosts of Girlfriends Past | $96,078 | - | 34 | - | $2,825 | $157,204 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 7 | 4 | Drag Me to Hell | $86,786 | -31.5% | 30 | -1 | $2,892 | $263,270 | 2 | Belga Films | false | false |
| 8 | 6 | Angels & Demons | $75,933 | -37.7% | 56 | -42 | $1,355 | $4,285,470 | 8 | Sony Pictures Releasing | false | false |
| 9 | 8 | State of Play | $47,424 | -41.4% | 28 | -2 | $1,693 | $349,349 | 3 | Universal Pictures International (UPI) | false | false |
| 10 | 9 | The French Kissers | $44,945 | -42.2% | 18 | - | $2,496 | $153,930 | 2 | Alternative Films | false | false |
| 11 | 5 | Night at the Museum: Battle of the Smithsonian | $41,938 | -66.8% | 30 | -20 | $1,397 | $2,246,164 | 7 | 20th Century Fox International | false | false |
| 12 | 7 | Terminator Salvation | $35,109 | -60.3% | 50 | -27 | $702 | $1,509,179 | 5 | Sony Pictures Releasing | false | false |
| 13 | 10 | Coraline | $17,803 | -68.3% | 29 | -18 | $613 | $395,369 | 4 | Universal Pictures International (UPI) | false | false |
| 14 | 15 | Looking for Eric | $13,425 | -30.7% | 15 | -2 | $895 | $191,707 | 4 | Cinéart | false | false |
| 15 | 11 | 17 Again | $13,054 | -49.2% | 17 | -7 | $767 | $1,227,329 | 9 | Kinepolis Film Distribution (KFD) | false | false |
| 16 | - | Crank: High Voltage | $11,569 | - | 7 | - | $1,652 | $13,396 | 1 | Sony Pictures Releasing | true | false |
| 17 | 13 | Don't Look Back | $10,875 | -46.9% | 9 | -2 | $1,208 | $63,538 | 2 | Cinéart | false | false |
| 18 | 12 | A Town Called Panic | $10,318 | -49.7% | 13 | -6 | $793 | $95,493 | 3 | Cinéart | false | false |
| 19 | - | Sans rancune! | $9,499 | - | 13 | - | $730 | $9,499 | 1 | N/A | true | false |
| 20 | 18 | The Girl with the Dragon Tattoo | $6,055 | -49.7% | 14 | -27 | $432 | $548,795 | 7 | Benelux Film Distributors | false | false |
| 21 | 17 | Make It Happen | $5,102 | -62.8% | 5 | - | $1,020 | $364,142 | 13 | Benelux Film Distributors | false | false |
| 22 | - | Mid-August Lunch | $4,265 | - | 6 | - | $710 | $59,583 | 4 | ABC Distribution | false | false |
| 23 | - | Round Da Way | $3,489 | - | 6 | - | $581 | $22,508 | 2 | Les Films de l'Elysée | false | false |
| 24 | 16 | Beverly Hills Chihuahua | $3,397 | -75.9% | 13 | -21 | $261 | $1,332,428 | 14 | Walt Disney Pictures | false | false |
| 25 | 21 | My Bloody Valentine | $2,847 | -46.2% | 2 | -3 | $1,423 | $606,093 | 10 | Kinepolis Film Distribution (KFD) | false | false |
| 26 | - | The Other One 2009 Re-release | $2,804 | - | 4 | - | $701 | $2,804 | 1 | Cinéart | true | false |
| 27 | 28 | Fast & Furious | $2,226 | -31.2% | 1 | -3 | $2,226 | $3,349,786 | 13 | Universal Pictures International (UPI) | false | false |
| 28 | 22 | Star Trek | $2,142 | -55.3% | 7 | -6 | $306 | $1,021,572 | 9 | Universal Pictures International (UPI) | false | false |
| 29 | 25 | Coco Before Chanel | $1,773 | -51.9% | 9 | -1 | $197 | $649,349 | 11 | Kinepolis Film Distribution (KFD) | false | false |
| 30 | 26 | Sunshine Cleaning | $1,686 | -53.8% | 5 | +1 | $337 | $133,355 | 5 | A-Film Distribution | false | false |
| 31 | - | The Secret of Moonacre | $1,669 | - | 3 | - | $556 | $76,300 | 20 | Kinepolis Film Distribution (KFD) | false | false |
| 32 | 29 | The Last House on the Left | $1,358 | -51.5% | 2 | -1 | $679 | $398,388 | 11 | Universal Pictures International (UPI) | false | false |
| 33 | 30 | Let's Make Money | $1,257 | -53.3% | 3 | - | $419 | $14,887 | 2 | Cinéart | false | false |
| 34 | 23 | Knowing | $1,072 | -77.5% | 1 | -3 | $1,072 | $2,700,532 | 14 | Belga Films | false | false |
| 35 | 32 | Home | $912 | -44.2% | 5 | - | $182 | $56,402 | 5 | Belga Films | false | false |
| 36 | 20 | Monsters vs. Aliens | $738 | -91.7% | 8 | -18 | $92 | $1,796,363 | 14 | Universal Pictures International (UPI) | false | false |
| 37 | 24 | He's Just Not That Into You | $625 | -86.3% | 1 | -4 | $625 | $1,183,482 | 11 | Paradiso Entertainment | false | false |
| 38 | 27 | Sister Smile | $532 | -84.4% | 13 | -8 | $40 | $578,206 | 9 | Kinepolis Film Distribution (KFD) | false | false |
| 39 | 36 | The Reader | $366 | +39.2% | 1 | -8 | $366 | $883,720 | 18 | Benelux Film Distributors | false | false |
| 40 | 14 | X-Men Origins: Wolverine | $303 | -98.5% | 1 | -14 | $303 | $2,342,715 | 10 | 20th Century Fox International | false | false |
| 41 | 37 | Synecdoche, New York | $119 | -41.7% | 2 | +1 | $59 | $18,858 | 8 | Paradiso Entertainment | false | false |
| 42 | - | Soul Power | $74 | - | 2 | - | $37 | $202 | 1 | ABC Distribution | true | false |
