| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | The Hangover | $33,415,000 | $32,794,387 | -$620,613 | -1.9% | 3,355 | $105,389,000 | $104,768,489 | 2 | Warner Bros. | - |
| 2 | 2 | - | Up | $30,515,000 | $30,762,280 | +$247,280 | +0.8% | 3,886 | $187,179,000 | $187,425,989 | 3 | Walt Disney Studios Motion Pictures | - |
| 3 | 3 | - | The Taking of Pelham 123 | $25,000,000 | $23,373,102 | -$1,626,898 | -6.5% | 3,074 | $25,000,000 | $23,373,102 | 1 | Sony Pictures Releasing | - |
| 4 | 4 | - | Night at the Museum: Battle of the Smithsonian | $9,600,000 | $9,616,907 | +$16,907 | +0.2% | 3,365 | $143,447,000 | $143,463,712 | 4 | Twentieth Century Fox | - |
| 5 | 5 | - | Land of the Lost | $9,153,000 | $8,994,030 | -$158,970 | -1.7% | 3,534 | $34,980,000 | $34,820,550 | 2 | Universal Pictures | - |
| 6 | 6 | - | Imagine That | $5,700,000 | $5,503,519 | -$196,481 | -3.4% | 3,008 | $5,700,000 | $5,503,519 | 1 | Paramount Pictures | - |
| 7 | 7 | - | Star Trek | $5,600,000 | $5,454,563 | -$145,437 | -2.6% | 2,638 | $232,028,000 | $231,882,965 | 6 | Paramount Pictures | - |
| 8 | 8 | - | Terminator Salvation | $4,695,000 | $4,787,487 | +$92,487 | +2% | 2,650 | $113,831,000 | $113,923,159 | 4 | Warner Bros. | - |
| 9 | 9 | - | Angels & Demons | $4,200,000 | $4,111,457 | -$88,543 | -2.1% | 2,436 | $123,300,000 | $123,211,661 | 5 | Sony Pictures Releasing | - |
| 10 | 10 | - | Drag Me to Hell | $3,864,000 | $3,932,585 | +$68,585 | +1.8% | 2,273 | $35,146,000 | $35,214,475 | 3 | Universal Pictures | - |
| 11 | 11 | - | My Life in Ruins | $1,700,000 | $1,710,353 | +$10,353 | +0.6% | 1,165 | $6,361,000 | $6,371,636 | 2 | Fox Searchlight Pictures | - |
| 12 | 12 | - | X-Men Origins: Wolverine | $915,000 | $933,573 | +$18,573 | +2% | 799 | $176,132,000 | $176,150,506 | 7 | Twentieth Century Fox | - |
| 13 | 13 | - | Dance Flick | $730,000 | $721,431 | -$8,569 | -1.2% | 810 | $24,159,000 | $24,150,493 | 4 | Paramount Pictures | - |
| 14 | 14 | - | Away We Go | $554,000 | $560,815 | +$6,815 | +1.2% | 45 | $751,000 | $757,635 | 2 | Focus Features | - |
| 15 | 15 | - | Ghosts of Girlfriends Past | $455,000 | $466,250 | +$11,250 | +2.5% | 545 | $52,885,000 | $52,895,861 | 7 | Warner Bros. | - |
| 16 | 17 | +1 | Easy Virtue | $323,000 | $299,716 | -$23,284 | -7.2% | 90 | $1,028,000 | $1,004,798 | 4 | Sony Pictures Classics | - |
| 17 | 18 | +1 | The Brothers Bloom | $295,000 | $296,404 | +$1,404 | +0.5% | 173 | $2,507,000 | $2,508,778 | 5 | Summit Entertainment | - |
| 18 | 20 | +2 | Monsters vs. Aliens | $194,000 | $205,122 | +$11,122 | +5.7% | 255 | $195,210,000 | $195,220,748 | 12 | DreamWorks | - |
| 19 | 23 | +4 | The Soloist | $157,000 | $158,765 | +$1,765 | +1.1% | 256 | $31,010,000 | $31,011,682 | 8 | DreamWorks | - |
| 20 | 25 | +5 | Moon | $145,000 | $136,046 | -$8,954 | -6.2% | 8 | $145,000 | $136,046 | 1 | Sony Pictures Classics | - |
| 21 | 22 | +1 | Fast & Furious | $144,000 | $162,625 | +$18,625 | +12.9% | 234 | $154,628,000 | $154,647,005 | 11 | Universal Pictures | - |
| 22 | 26 | +4 | Summer Hours | $125,000 | $123,344 | -$1,656 | -1.3% | 50 | $965,000 | $963,236 | 5 | IFC Films | - |
| 23 | 28 | +5 | Every Little Step | $110,000 | $99,597 | -$10,403 | -9.5% | 70 | $1,238,000 | $1,227,520 | 9 | Sony Pictures Classics | - |
| 24 | 31 | +7 | Next Day Air | $100,000 | $86,549 | -$13,451 | -13.5% | 153 | $9,859,000 | $9,845,360 | 6 | Summit Entertainment | - |
| 25 | 29 | +4 | State of Play | $88,000 | $97,945 | +$9,945 | +11.3% | 175 | $36,955,000 | $36,965,395 | 9 | Universal Pictures | - |
| 26 | 34 | +8 | Knowing | $65,000 | $73,565 | +$8,565 | +13.2% | 122 | $79,666,000 | $79,674,604 | 13 | Summit Entertainment | - |
| 27 | 35 | +8 | Food, Inc. | $63,000 | $60,513 | -$2,487 | -3.9% | 3 | $63,000 | $60,513 | 1 | Magnolia Pictures | - |
| 28 | 37 | +9 | Rudo y Cursi | $53,800 | $46,044 | -$7,756 | -14.4% | 59 | $1,700,000 | $1,692,511 | 6 | Sony Pictures Classics | - |
| 29 | 36 | +7 | Valentino: The Last Emperor | $48,400 | $54,325 | +$5,925 | +12.2% | 33 | $1,375,000 | $1,381,325 | 13 | Truly Indie | - |
| 30 | 42 | +12 | Sugar | $36,100 | $36,510 | +$410 | +1.1% | 44 | $1,000,000 | $1,000,834 | 11 | Sony Pictures Classics | - |
| 31 | 45 | +14 | Is Anybody There? | $32,800 | $34,357 | +$1,557 | +4.7% | 63 | $1,950,000 | $1,951,487 | 9 | - | - |
| 32 | 48 | +16 | Tetro | $31,300 | $30,504 | -$796 | -2.5% | 2 | $38,200 | $37,334 | 1 | American Zoetrope | - |
| 33 | 51 | +18 | Tyson | $30,000 | $26,177 | -$3,823 | -12.7% | 30 | $793,000 | $788,822 | 8 | Sony Pictures Classics | - |
| 34 | 53 | +19 | Sin Nombre | $21,900 | $22,542 | +$642 | +2.9% | 33 | $2,479,000 | $2,479,794 | 13 | Focus Features | - |
| 35 | 55 | +20 | Anvil: The Story of Anvil | $19,500 | $18,960 | -$540 | -2.8% | 17 | $567,000 | $566,609 | 10 | Abramorama | - |
| 36 | 57 | +21 | Unmistaken Child | $17,300 | $17,470 | +$170 | +1% | 3 | $32,100 | $32,305 | 2 | Oscilloscope | - |
| 37 | 59 | +22 | War Eagle, Arkansas | $15,200 | $16,467 | +$1,267 | +8.3% | 7 | $15,200 | $16,467 | 1 | Hannover House | - |
| 38 | 65 | +27 | The Limits of Control | $13,600 | $13,814 | +$214 | +1.6% | 18 | $395,000 | $395,045 | 7 | Focus Features | - |
| 39 | 72 | +33 | Coraline | $11,700 | $10,103 | -$1,597 | -13.6% | 25 | $75,241,000 | $75,239,621 | 19 | Focus Features | - |
| 40 | 73 | +33 | Enlighten Up! | $10,900 | $9,558 | -$1,342 | -12.3% | 6 | $209,000 | $207,677 | 40 | Balcony Releasing | - |
| 41 | 68 | +27 | Call of the Wild | $10,500 | $10,713 | +$213 | +2% | 14 | $10,500 | $11,245 | 1 | Vivendi Entertainment | - |
| 42 | 102 | +60 | Treeless Mountain | $2,000 | $1,200 | -$800 | -40% | 2 | $45,400 | $44,591 | 8 | Oscilloscope | - |
| 43 | 100 | +57 | Burma VJ: Reporting from a Closed Country | $2,000 | $1,500 | -$500 | -25% | 2 | $32,000 | $31,450 | 4 | Oscilloscope | - |
