| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 2 | +1 | Up | $44,244,000 | $44,138,266 | -$105,734 | -0.2% | 3,818 | $137,316,000 | $137,210,701 | 2 | Walt Disney Studios Motion Pictures | - |
| 2 | 1 | -1 | The Hangover | $43,275,000 | $44,979,319 | +$1,704,319 | +3.9% | 3,269 | $43,275,000 | $44,979,319 | 1 | Warner Bros. | - |
| 3 | 3 | - | Land of the Lost | $19,524,000 | $18,837,350 | -$686,650 | -3.5% | 3,521 | $19,524,000 | $18,837,350 | 1 | Universal Pictures | - |
| 4 | 4 | - | Night at the Museum: Battle of the Smithsonian | $14,650,000 | $14,634,988 | -$15,012 | -0.1% | 3,807 | $127,341,000 | $127,326,188 | 3 | Twentieth Century Fox | - |
| 5 | 5 | - | Star Trek | $8,400,000 | $8,310,480 | -$89,520 | -1.1% | 3,202 | $222,802,000 | $222,712,175 | 5 | Paramount Pictures | - |
| 6 | 6 | - | Terminator Salvation | $8,175,000 | $8,248,387 | +$73,387 | +0.9% | 3,304 | $105,495,000 | $105,568,008 | 3 | Warner Bros. | - |
| 7 | 7 | - | Drag Me to Hell | $7,342,000 | $7,040,550 | -$301,450 | -4.1% | 2,510 | $28,534,000 | $28,233,230 | 2 | Universal Pictures | - |
| 8 | 8 | - | Angels & Demons | $6,500,000 | $6,550,282 | +$50,282 | +0.8% | 2,925 | $116,125,000 | $116,174,931 | 4 | Sony Pictures Releasing | - |
| 9 | 9 | - | My Life in Ruins | $3,225,000 | $3,223,161 | -$1,839 | <0.1% | 1,164 | $3,225,000 | $3,223,161 | 1 | - | - |
| 10 | 10 | - | Dance Flick | $2,000,000 | $1,958,725 | -$41,275 | -2.1% | 1,707 | $22,667,000 | $22,625,733 | 3 | Paramount Pictures | - |
| 11 | 11 | - | X-Men Origins: Wolverine | $1,860,000 | $1,927,096 | +$67,096 | +3.6% | 1,391 | $174,280,000 | $174,347,386 | 6 | Twentieth Century Fox | - |
| 12 | 12 | - | Ghosts of Girlfriends Past | $945,000 | $932,181 | -$12,819 | -1.4% | 879 | $51,932,000 | $51,919,132 | 6 | Warner Bros. | - |
| 13 | 13 | - | The Brothers Bloom | $425,000 | $412,771 | -$12,229 | -2.9% | 173 | $2,038,000 | $2,025,712 | 4 | Summit Entertainment | - |
| 14 | 14 | - | Fast & Furious | $298,000 | $286,795 | -$11,205 | -3.8% | 284 | $154,368,000 | $154,356,665 | 10 | Universal Pictures | - |
| 15 | 15 | - | Monsters vs. Aliens | $275,000 | $270,873 | -$4,127 | -1.5% | 313 | $194,858,000 | $194,854,481 | 11 | DreamWorks | - |
| 16 | 16 | - | The Soloist | $270,000 | $264,531 | -$5,469 | -2% | 306 | $30,732,000 | $30,726,123 | 7 | DreamWorks | - |
| 17 | 22 | +5 | Easy Virtue | $219,000 | $202,920 | -$16,080 | -7.3% | 46 | $628,000 | $611,346 | 3 | Sony Pictures Classics | - |
| 18 | 24 | +6 | Summer Hours | $164,000 | $149,344 | -$14,656 | -8.9% | 48 | $791,000 | $776,231 | 4 | IFC Films | - |
| 19 | 25 | +6 | State of Play | $145,000 | $138,805 | -$6,195 | -4.3% | 217 | $36,797,000 | $36,790,345 | 8 | Universal Pictures | - |
| 20 | 26 | +6 | Away We Go | $143,000 | $130,411 | -$12,589 | -8.8% | 4 | $143,000 | $130,411 | 1 | Focus Features | - |
| 21 | 27 | +6 | Next Day Air | $132,000 | $127,962 | -$4,038 | -3.1% | 209 | $9,705,000 | $9,700,661 | 5 | Summit Entertainment | - |
| 22 | 28 | +6 | Every Little Step | $101,000 | $95,476 | -$5,524 | -5.5% | 54 | $1,077,000 | $1,071,900 | 8 | Sony Pictures Classics | - |
| 23 | 30 | +7 | Rudo y Cursi | $95,600 | $89,465 | -$6,135 | -6.4% | 94 | $1,608,000 | $1,601,828 | 5 | Sony Pictures Classics | - |
| 24 | 32 | +8 | Departures | $88,100 | $86,214 | -$1,886 | -2.1% | 16 | $192,000 | $191,153 | 2 | Regent Releasing | - |
| 25 | 29 | +4 | Knowing | $84,000 | $93,035 | +$9,035 | +10.8% | 152 | $79,536,000 | $79,545,127 | 12 | Summit Entertainment | - |
| 26 | 31 | +5 | Fighting | $78,000 | $86,375 | +$8,375 | +10.7% | 144 | $23,028,000 | $23,036,320 | 7 | Universal Pictures | - |
| 27 | 35 | +8 | Is Anybody There? | $66,100 | $69,554 | +$3,454 | +5.2% | 86 | $1,877,000 | $1,880,551 | 8 | - | - |
| 28 | 36 | +8 | Valentino: The Last Emperor | $58,000 | $52,537 | -$5,463 | -9.4% | 33 | $1,291,000 | $1,289,611 | 12 | Truly Indie | - |
| 29 | 37 | +8 | Sunshine Cleaning | $50,000 | $47,361 | -$2,639 | -5.3% | 71 | $11,772,000 | $11,769,422 | 13 | Overture Films | - |
| 30 | 44 | +14 | Sugar | $43,800 | $30,637 | -$13,163 | -30.1% | 42 | $964,000 | $950,815 | 10 | Sony Pictures Classics | - |
| 31 | 39 | +8 | Seraphine | $39,500 | $38,637 | -$863 | -2.2% | 6 | $39,500 | $38,637 | 1 | Music Box Films | - |
| 32 | 43 | +11 | Tyson | $34,700 | $31,988 | -$2,712 | -7.8% | 32 | $746,000 | $742,992 | 7 | Sony Pictures Classics | - |
| 33 | 42 | +9 | Sin Nombre | $30,400 | $32,547 | +$2,147 | +7.1% | 39 | $2,434,000 | $2,436,392 | 12 | Focus Features | - |
| 34 | 47 | +13 | The Limits of Control | $25,700 | $27,454 | +$1,754 | +6.8% | 27 | $360,000 | $362,032 | 6 | Focus Features | - |
| 35 | 52 | +17 | Anvil | $20,500 | $21,229 | +$729 | +3.6% | 18 | $536,000 | $536,921 | 9 | Abramorama | - |
| 36 | 56 | +20 | Adoration | $17,500 | $14,455 | -$3,045 | -17.4% | 20 | $192,000 | $188,962 | 5 | Sony Pictures Classics | - |
| 37 | 58 | +21 | O'Horten | $14,100 | $13,139 | -$961 | -6.8% | 7 | $77,100 | $76,195 | 3 | Sony Pictures Classics | - |
| 38 | 61 | +23 | Enlighten Up! | $10,500 | $9,805 | -$695 | -6.6% | 7 | $186,000 | $192,154 | 39 | Balcony Releasing | - |
| 39 | 62 | +23 | Tennessee | $10,000 | $9,438 | -$562 | -5.6% | 15 | $10,000 | $9,438 | 1 | Vivendi Entertainment | - |
| 40 | 57 | +17 | Coraline | $9,650 | $13,694 | +$4,044 | +41.9% | 29 | $75,214,000 | $75,218,093 | 18 | Focus Features | - |
| 41 | 65 | +24 | Paris 36 | $7,900 | $9,134 | +$1,234 | +15.6% | 25 | $830,000 | $831,421 | 10 | Sony Pictures Classics | - |
| 42 | 70 | +28 | Unmistaken Child | $6,000 | $6,293 | +$293 | +4.9% | 1 | $9,500 | $9,728 | 1 | Oscilloscope | - |
| 43 | 80 | +37 | Burma VJ: Reporting from a Closed Country | $4,170 | $3,974 | -$196 | -4.7% | 2 | $26,500 | $26,309 | 3 | Oscilloscope | - |
| 44 | 89 | +45 | Treeless Mountain | $2,660 | $2,226 | -$434 | -16.3% | 2 | $42,900 | $42,505 | 7 | Oscilloscope | - |
| 45 | 64 | +19 | Herb & Dorothy | $1,000 | $9,242 | +$8,242 | +824.2% | 2 | $10,000 | $9,242 | 1 | Arthouse Films | - |
