| TW | LW | Total | %± LW | Share | Releases | #1 Release
| Gross | % of Total | Week | Distributor
| New This Week
|
|---|
| 1 | 3 | $54,693,952 | +186.6% | 33% | 8 | The Hangover | $44,979,319 | 82.2% | 1 | Warner Bros. | - |
| 2 | 1 | $44,771,800 | -35.3% | 27% | 6 | Up | $44,138,266 | 98.6% | 2 | Walt Disney Studios Motion Pictures | - |
| 3 | 5 | $26,389,875 | +61% | 15.9% | 5 | Land of the Lost | $18,837,350 | 71.4% | 1 | Universal Pictures | - |
| 4 | 2 | $16,601,192 | -41.4% | 10% | 4 | Night at the Museum: Battle of the Smithsonian | $14,634,988 | 88.2% | 3 | Twentieth Century Fox | - |
| 5 | 4 | $10,269,205 | -40.8% | 6.2% | 2 | Star Trek | $8,310,480 | 80.9% | 5 | Paramount Pictures | - |
| 6 | 6 | $6,550,282 | -42.3% | 4% | 1 | Angels & Demons | $6,550,282 | 100% | 4 | Sony Pictures Releasing | - |
| 8 | 7 | $633,768 | -33.9% | 0.4% | 3 | The Brothers Bloom | $412,771 | 65.1% | 4 | Summit Entertainment | - |
| 9 | 8 | $535,404 | -43.1% | 0.3% | 2 | Monsters vs. Aliens | $270,873 | 50.6% | 11 | DreamWorks | - |
| 10 | 10 | $488,798 | -17.5% | 0.3% | 10 | Easy Virtue | $202,920 | 41.5% | 3 | Sony Pictures Classics | - |
| 11 | 9 | $258,092 | -60.7% | 0.2% | 1 | Obsessed | $258,092 | 100% | 7 | Screen Gems | - |
| 12 | 15 | $204,106 | +97.8% | 0.1% | 4 | Away We Go | $130,411 | 63.9% | 1 | Focus Features | - |
| 13 | 11 | $200,212 | -21.7% | 0.1% | 6 | Summer Hours | $149,344 | 74.6% | 4 | IFC Films | - |
| 14 | 14 | $119,477 | +14.4% | <0.1% | 7 | Departures | $86,214 | 72.2% | 2 | Regent Releasing | - |
| 15 | 12 | $100,507 | -34.3% | <0.1% | 6 | The Girlfriend Experience | $72,669 | 72.3% | 3 | Magnolia Pictures | - |
| 16 | 13 | $69,554 | -44.5% | <0.1% | 1 | Is Anybody There? | $69,554 | 100% | 8 | - | - |
| 17 | 24 | $58,082 | +130.1% | <0.1% | 3 | Seraphine | $38,637 | 66.5% | 1 | Music Box Films | - |
| 18 | 17 | $52,537 | -23.1% | <0.1% | 1 | Valentino: The Last Emperor | $52,537 | 100% | 12 | Truly Indie | - |
| 19 | 16 | $47,361 | -49.8% | <0.1% | 1 | Sunshine Cleaning | $47,361 | 100% | 13 | Overture Films | - |
| 20 | 20 | $46,853 | +2.6% | <0.1% | 3 | Magnificent Desolation: Walking on the Moon | $23,931 | 51.1% | 194 | IMAX | - |
| 21 | 19 | $44,076 | -24.7% | <0.1% | 3 | Goodbye Solo | $43,841 | 99.5% | 11 | Roadside Attractions | - |
| 22 | 22 | $28,577 | -7.3% | <0.1% | 1 | Dolphins and Whales 3D: Tribes of the Ocean | $28,577 | 100% | 69 | 3D Entertainment | - |
| 23 | 23 | $27,036 | -11.7% | <0.1% | 2 | Sea Monsters: A Prehistoric Adventure | $18,134 | 67.1% | 88 | National Geographic Entertainment | - |
| 24 | 18 | $25,469 | -61.7% | <0.1% | 3 | Management | $19,042 | 74.8% | 4 | The Samuel Goldwyn Company | - |
| 25 | 29 | $25,033 | +181.7% | <0.1% | 1 | Revanche | $25,033 | 100% | 6 | Janus Films | - |
| 26 | 21 | $21,229 | -37.7% | <0.1% | 1 | Anvil | $21,229 | 100% | 9 | Abramorama | - |
| 27 | 26 | $12,493 | +12% | <0.1% | 3 | Unmistaken Child | $6,293 | 50.4% | 1 | Oscilloscope | - |
| 28 | 31 | $11,562 | +59.8% | <0.1% | 3 | Fados | $6,229 | 53.9% | 14 | Zeitgeist Films | - |
| 29 | 36 | $10,861 | +350.1% | <0.1% | 2 | Downloading Nancy | $10,324 | 95.1% | 1 | Strand Releasing | - |
| 30 | 25 | $9,805 | -17.4% | <0.1% | 1 | Enlighten Up! | $9,805 | 100% | 39 | Balcony Releasing | - |
| 32 | 28 | $9,311 | -7% | <0.1% | 3 | Rolling | $5,380 | 57.8% | 10 | Indican Pictures | - |
| 33 | 27 | $9,243 | -10.3% | <0.1% | 1 | Lymelife | $9,243 | 100% | 9 | Screen Media Films | - |
| 35 | 33 | $6,505 | +102.8% | <0.1% | 2 | 24 City | $6,082 | 93.5% | 1 | The Cinema Guild | - |
| 36 | 40 | $4,644 | +419.5% | <0.1% | 1 | Throw Down Your Heart | $4,644 | 100% | 13 | Argot Pictures | - |
| 38 | 30 | $4,133 | -49.3% | <0.1% | 1 | Pressure Cooker | $4,133 | 100% | 2 | - | - |
| 39 | 38 | $3,905 | +81.6% | <0.1% | 3 | Harvard Beats Yale 29-29 | $2,450 | 62.7% | 29 | Kino International | - |
| 41 | 34 | $1,618 | -49.1% | <0.1% | 1 | Gigantic | $1,618 | 100% | 10 | First Independent Pictures | - |
| 42 | 35 | $1,205 | -58% | <0.1% | 1 | Tokyo! | $1,205 | 100% | 14 | Liberation Entertainment | - |
| 43 | 37 | $735 | -67.3% | <0.1% | 1 | Not Forgotten | $735 | 100% | 6 | Anchor Bay Films | - |
| 46 | 41 | $305 | -52% | <0.1% | 1 | Z | $305 | 100% | 13 | Rialto Pictures | - |
| 47 | 32 | $244 | -92.9% | <0.1% | 1 | Ballerina | $244 | 100% | 21 | First Run | - |
| 48 | 43 | $207 | -25.5% | <0.1% | 1 | Battle for Terra | $207 | 100% | 6 | Lionsgate | - |
