| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Night at the Museum: Battle of the Smithsonian | $206,096 | -18.2% | 80 | - | $2,576 | $529,215 | 2 | NuMetro Distribution | false | false |
| 2 | - | Duplicity | $121,729 | - | 43 | - | $2,830 | $121,729 | 1 | United International Pictures | true | false |
| 3 | 2 | Angels & Demons | $103,428 | -25.5% | 78 | -2 | $1,326 | $696,749 | 3 | Ster-Kinekor Pictures | false | false |
| 4 | 3 | Ghosts of Girlfriends Past | $75,497 | -19.3% | 47 | - | $1,606 | $461,003 | 3 | NuMetro Distribution | false | false |
| 5 | 4 | X-Men Origins: Wolverine | $56,076 | -17.6% | 72 | -7 | $778 | $1,187,829 | 5 | NuMetro Distribution | false | false |
| 6 | 5 | White Wedding | $41,573 | -18.4% | 34 | -4 | $1,222 | $512,677 | 5 | Ster-Kinekor Pictures | false | false |
| 7 | 7 | 17 Again | $37,158 | -5.1% | 49 | -5 | $758 | $1,127,769 | 7 | NuMetro Distribution | false | false |
| 8 | 6 | Hannah Montana: The Movie | $36,655 | -23.8% | 56 | -10 | $654 | $633,384 | 5 | Ster-Kinekor Pictures | false | false |
| 9 | 8 | Star Trek | $26,619 | -26.1% | 30 | -6 | $887 | $298,191 | 4 | United International Pictures | false | false |
| 10 | 9 | The Last House on the Left | $22,548 | -14.6% | 25 | - | $901 | $64,839 | 2 | United International Pictures | false | false |
| 11 | 11 | Coraline | $13,965 | -16.9% | 11 | -9 | $1,269 | $128,834 | 4 | United International Pictures | false | false |
| 12 | 10 | Fast & Furious | $11,333 | -45.7% | 30 | -17 | $377 | $1,825,741 | 8 | United International Pictures | false | false |
| 13 | - | The Uninvited | $10,805 | - | 10 | - | $1,080 | $10,805 | 1 | United International Pictures | true | false |
| 14 | 17 | The International | $9,410 | +28.8% | 15 | +5 | $627 | $216,818 | 6 | Ster-Kinekor Pictures | false | false |
| 15 | - | Asterix at the Olympic Games | $7,870 | - | 12 | - | $655 | $7,870 | 1 | Ster-Kinekor Pictures | true | false |
| 16 | 12 | Slumdog Millionaire | $7,622 | -34.4% | 16 | -3 | $476 | $1,201,287 | 13 | Ster-Kinekor Pictures | false | false |
| 17 | 13 | The Unborn | $7,036 | -21.2% | 12 | -3 | $586 | $47,831 | 3 | United International Pictures | false | false |
| 18 | 15 | The Reader | $5,915 | -21.7% | 9 | - | $657 | $309,634 | 10 | Ster-Kinekor Pictures | false | false |
| 19 | 14 | Blindness | $5,275 | -32.7% | 10 | - | $527 | $18,546 | 2 | Ster-Kinekor Pictures | false | false |
| 20 | - | Miss March | $4,594 | - | 5 | - | $918 | $4,594 | 1 | NuMetro Distribution | true | false |
| 21 | 16 | Hotel for Dogs | $4,379 | -40.4% | 13 | -10 | $336 | $333,902 | 7 | United International Pictures | false | false |
| 22 | 21 | Street Fighter: The Legend of Chun-Li | $2,862 | -19.8% | 10 | -4 | $286 | $65,983 | 4 | NuMetro Distribution | false | false |
| 23 | 22 | Gran Torino | $1,619 | -36.7% | 3 | -5 | $539 | $294,552 | 10 | NuMetro Distribution | false | false |
| 24 | 24 | Then She Found Me | $574 | -29.8% | 1 | - | $574 | $9,871 | 13 | NuMetro Distribution | false | false |
