| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Night at the Museum: Battle of the Smithsonian | $30,302 | -28.9% | 9 | - | $3,366 | $86,006 | 2 | 20th Century Fox International | false | false |
| 2 | 2 | Angels & Demons | $24,264 | -32.4% | 8 | - | $3,033 | $164,263 | 3 | Sony Pictures Releasing | false | false |
| 3 | - | My Bloody Valentine | $21,571 | - | 2 | - | $10,785 | $21,571 | 12 | - | false | false |
| 4 | - | Fast & Furious | $9,345 | - | 5 | - | $1,869 | $9,345 | 9 | United International Pictures | false | false |
| 5 | - | He's Just Not That Into You | $5,422 | - | 3 | - | $1,807 | $5,422 | 6 | PlayArte Pictures | false | false |
| 6 | 3 | X-Men Origins: Wolverine | $5,220 | -31.1% | 6 | -2 | $870 | $142,152 | 5 | 20th Century Fox International | false | false |
| 7 | - | Che: Part Two | $3,151 | - | 1 | - | $3,151 | $3,151 | 1 | N/A | true | false |
| 8 | 4 | Changeling | $2,207 | -19.2% | 4 | - | $551 | $5,895 | 2 | United International Pictures | false | false |
| 9 | 9 | Donkey Xote | $1,572 | +28.2% | 2 | - | $786 | $16,698 | 5 | - | false | false |
| 10 | 6 | Star Trek | $1,548 | -20.2% | 2 | -2 | $774 | $29,986 | 4 | United International Pictures | false | false |
| 11 | 7 | Lonely Hearts | $1,075 | -37.9% | 1 | - | $1,075 | $3,412 | 2 | - | false | false |
| 12 | 8 | The Boy in the Striped Pajamas | $1,013 | -24.1% | 1 | -1 | $1,013 | $30,545 | 8 | Walt Disney Pictures | false | false |
| 13 | 10 | Race to Witch Mountain | $628 | -36.3% | 1 | -1 | $628 | $110,522 | 10 | Walt Disney Pictures | false | false |
| 14 | 11 | The Diving Bell and the Butterfly | $427 | -52.4% | 1 | - | $427 | $14,254 | 6 | N/A | false | false |
| 15 | 5 | Confessions of a Shopaholic | $360 | -82.2% | 1 | -1 | $360 | $21,559 | 8 | Walt Disney Pictures | false | false |
