| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 33 | 38 | French Film | $553 | -82.5% | 2 | -1 | $276 | $6,478 | 2 | Vertigo Films | false | false |
| 32 | - | Louise Bourgeois | $578 | - | 1 | - | $578 | $578 | 1 | Revolver Entertainment | true | false |
| 31 | 44 | Good | $979 | -48.1% | 2 | -3 | $489 | $89,539 | 6 | Lionsgate Films | false | false |
| 30 | 36 | Sounds Like Teen Spirit | $1,247 | -68.9% | 3 | -4 | $415 | $26,786 | 3 | - | false | false |
| 29 | 29 | Fifty Dead Men Walking | $1,247 | -80.8% | 3 | -6 | $415 | $610,531 | 7 | - | false | false |
| 28 | 39 | Little Ashes | $2,126 | -27.9% | 2 | +1 | $1,063 | $19,429 | 3 | N/A | false | false |
| 27 | 35 | Shifty | $2,475 | -42.5% | 4 | -1 | $618 | $223,695 | 5 | - | false | false |
| 26 | 37 | Slumdog Millionaire | $3,575 | -8.1% | 3 | -1 | $1,191 | $50,390,803 | 20 | Pathé | false | false |
| 25 | 33 | The Young Victoria | $3,691 | -23.4% | 2 | -4 | $1,845 | $7,820,650 | 12 | Momentum Pictures | false | false |
| 24 | - | Objectified | $7,185 | - | 1 | - | $7,185 | $7,185 | 1 | N/A | true | false |
| 23 | 25 | The Boat That Rocked | $7,574 | -41.6% | 5 | -9 | $1,514 | $9,722,961 | 8 | Universal Pictures International (UPI) | false | false |
| 22 | 31 | The Damned United | $7,579 | +36% | 8 | - | $947 | $3,450,057 | 9 | Sony Pictures Releasing | false | false |
| 21 | - | Pierrot the Fool 2009 Re-release | $9,859 | - | 3 | - | $3,286 | $9,859 | 1 | British Film Institute (BFI) | true | false |
| 20 | 18 | Is Anybody There? | $12,711 | -56.6% | 18 | -14 | $706 | $614,220 | 4 | Optimum Releasing | false | false |
| 19 | - | A Girl Cut in Two | $13,036 | - | 5 | - | $2,607 | $13,036 | 1 | Artificial Eye | true | false |
| 18 | - | Everlasting Moments | $15,177 | - | 7 | - | $2,168 | $15,177 | 1 | Icon Film Distribution | true | false |
| 17 | 14 | Chéri | $27,437 | -69.7% | 25 | -51 | $1,097 | $532,396 | 3 | Warner Bros. | false | false |
| 16 | - | Mark of an Angel | $34,545 | - | 13 | - | $2,657 | $34,545 | 1 | - | true | false |
| 15 | 13 | In the Loop | $53,109 | -57.6% | 32 | -31 | $1,659 | $3,180,868 | 6 | Optimum Releasing | false | false |
| 14 | - | Awaydays | $62,180 | - | 46 | - | $1,351 | $62,180 | 1 | Optimum Releasing | true | false |
| 13 | 12 | I Love You, Man | $74,953 | -52.6% | 56 | -49 | $1,338 | $6,420,620 | 6 | Paramount Pictures International | false | false |
| 12 | 9 | Monsters vs. Aliens | $110,549 | -71.5% | 332 | -22 | $332 | $33,225,127 | 8 | Paramount Pictures International | false | false |
| 11 | 11 | Synecdoche, New York | $111,593 | -40.3% | 39 | +9 | $2,861 | $422,303 | 2 | Revolver Entertainment | false | false |
| 10 | 8 | State of Play | $141,566 | -66.8% | 126 | -166 | $1,123 | $8,607,670 | 5 | Universal Pictures International (UPI) | false | false |
| 9 | 7 | Ghosts of Girlfriends Past | $259,461 | -64.3% | 237 | -99 | $1,094 | $6,228,898 | 4 | Entertainment Film Distributors | false | false |
| 8 | - | Tormented | $453,478 | - | 234 | - | $1,937 | $453,478 | 1 | Warner Bros. | true | false |
| 7 | 6 | Fighting | $476,472 | -68.3% | 291 | -2 | $1,637 | $2,675,998 | 2 | Universal Pictures International (UPI) | false | false |
| 6 | 5 | Hannah Montana: The Movie | $658,053 | -56.7% | 449 | +25 | $1,465 | $10,518,422 | 4 | Walt Disney Pictures | false | false |
| 5 | 3 | Coraline | $729,653 | -65% | 440 | +46 | $1,658 | $7,917,607 | 3 | Universal Pictures International (UPI) | false | false |
| 4 | 4 | X-Men Origins: Wolverine | $731,607 | -60.2% | 407 | -45 | $1,797 | $24,187,975 | 4 | 20th Century Fox International | false | false |
| 3 | 2 | Star Trek | $2,620,056 | -50.2% | 474 | -24 | $5,527 | $24,519,502 | 3 | Paramount Pictures International | false | false |
| 2 | 1 | Angels & Demons | $3,906,693 | -49.7% | 506 | - | $7,720 | $17,550,076 | 2 | Sony Pictures Releasing | false | false |
| 1 | - | Night at the Museum: Battle of the Smithsonian | $6,625,627 | - | 515 | - | $12,865 | $6,625,627 | 1 | 20th Century Fox International | true | false |
