| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Angels & Demons | $7,771,434 | -27.3% | 1,080 | - | $7,195 | $21,982,150 | 2 | Sony Pictures Releasing | false | false |
| 2 | - | Night at the Museum: Battle of the Smithsonian | $4,410,727 | - | 723 | - | $6,100 | $4,410,727 | 1 | 20th Century Fox International | true | false |
| 3 | 2 | Star Trek | $1,281,722 | -33.7% | 664 | -24 | $1,930 | $9,501,963 | 3 | Paramount Pictures International | false | false |
| 4 | 3 | 17 Again | $978,986 | -31.8% | 284 | +18 | $3,447 | $2,780,811 | 2 | Warner Bros. | false | false |
| 5 | - | My Bloody Valentine | $624,963 | - | 61 | - | $10,245 | $624,963 | 1 | Kinowelt Filmverleih | true | false |
| 6 | 4 | X-Men Origins: Wolverine | $468,943 | -41% | 470 | -212 | $997 | $8,508,897 | 4 | 20th Century Fox International | false | false |
| 7 | 5 | Slumdog Millionaire | $305,504 | -22.2% | 393 | -25 | $777 | $15,794,391 | 10 | Prokino Filmverleih | false | false |
| 8 | - | Sunshine Cleaning | $229,074 | - | 69 | - | $3,319 | $229,074 | 1 | Capelight Pictures | true | false |
| 9 | - | The Last House on the Left | $168,811 | - | 150 | - | $1,125 | $562,921 | - | Universal Pictures International (UPI) | - | false |
| 10 | 7 | Beverly Hills Chihuahua | $161,639 | -41.5% | 312 | - | $518 | $1,574,281 | 4 | Walt Disney Pictures | false | false |
| 11 | 8 | Duplicity | $131,629 | -47.2% | 195 | -76 | $675 | $2,371,671 | 4 | Universal Pictures International (UPI) | false | false |
| 12 | - | Public Enemy | $125,716 | - | 32 | - | $3,928 | $125,716 | 1 | Senator Film | true | false |
| 13 | 10 | Monsters vs. Aliens | $107,726 | -36.6% | 300 | -62 | $359 | $6,236,801 | 8 | Paramount Pictures International | false | false |
| 14 | 9 | The Crocodiles | $93,686 | -45% | 418 | -27 | $224 | $3,489,909 | 9 | Constantin Film | false | false |
| 15 | 12 | Princess Lillifee | $87,387 | -31.9% | 442 | -63 | $197 | $5,788,170 | 9 | Universum Film (UFA) | false | false |
| 16 | 11 | Paul Blart: Mall Cop | $85,010 | -43.9% | 247 | -60 | $344 | $12,612,538 | 9 | Sony Pictures Releasing | false | false |
| 17 | 13 | Crank: High Voltage | $63,182 | -42.4% | 175 | -120 | $361 | $6,568,508 | 6 | Universum Film (UFA) | false | false |
| 18 | 16 | Mid-August Lunch | $58,702 | -21% | 56 | +1 | $1,048 | $464,306 | 4 | Pandora Filmproduktion | false | false |
| 19 | 17 | Last Chance Harvey | $56,412 | -22.8% | 114 | - | $494 | $1,523,145 | 6 | Concorde Filmverleih | false | false |
| 20 | 18 | The First Day of the Rest of Your Life | $54,451 | -22.7% | 56 | - | $972 | $594,211 | 5 | Kinowelt Filmverleih | false | false |
| 21 | 22 | Gran Torino | $49,556 | -6.6% | 114 | -22 | $434 | $5,415,551 | 12 | Warner Bros. | false | false |
| 22 | 24 | I Saw the Sun 2009 Re-release | $47,755 | -3.9% | 39 | -13 | $1,224 | $1,523,545 | 6 | N/A | false | false |
| 23 | 15 | The Three Investigators and the Secret of Terror Castle | $46,559 | -44.1% | 238 | -34 | $195 | $3,784,572 | 10 | Walt Disney Pictures | false | false |
| 24 | 25 | The Reader | $44,931 | -8.5% | 151 | -31 | $297 | $18,636,856 | 13 | Senator Film | false | false |
| 25 | 20 | Phantom Pain | $39,495 | -40.3% | 122 | -24 | $323 | $653,220 | 4 | Warner Bros. | false | false |
| 26 | 19 | Fast & Furious | $36,641 | -47.8% | 95 | -88 | $385 | $15,402,470 | 8 | Universal Pictures International (UPI) | false | false |
| 27 | 14 | Eldorado | $31,394 | -64.4% | 23 | - | $1,364 | $137,764 | 2 | KOOL Filmdistribution | false | false |
| 28 | - | Adoration | $30,911 | - | 34 | - | $909 | $30,911 | - | X Verleih AG | - | false |
| 29 | 21 | Knowing | $30,603 | -47.2% | 114 | -62 | $268 | $4,738,580 | 7 | Concorde Filmverleih | false | false |
| 30 | 26 | John Rabe | $26,469 | -34.3% | 83 | -24 | $318 | $1,207,992 | 11 | Majestic Filmverleih | false | false |
| 31 | - | Dorfpunks | $22,636 | - | 37 | - | $611 | $361,446 | - | Piffl Medien | - | false |
| 32 | 27 | The Boy in the Striped Pajamas | $21,424 | -37.1% | 28 | -2 | $765 | $137,995 | 3 | Walt Disney Pictures | false | false |
| 33 | 29 | The Boat That Rocked | $20,926 | -32.8% | 63 | -20 | $332 | $1,803,889 | 6 | Universal Pictures International (UPI) | false | false |
| 34 | 23 | I Love You, Man | $18,887 | -62.5% | 84 | -87 | $224 | $1,384,912 | 5 | Paramount Pictures International | false | false |
| 35 | 33 | Lilly the Witch: The Dragon and the Magic Book | $16,239 | -28.8% | 109 | -25 | $148 | $8,264,019 | 14 | Walt Disney Pictures | false | false |
| 36 | 32 | Hilde | $16,067 | -34.9% | 71 | -15 | $226 | $3,357,354 | 11 | Warner Bros. | false | false |
| 37 | 35 | Twilight | $11,750 | -14.7% | 52 | -3 | $225 | $23,734,298 | 19 | Concorde Filmverleih | false | false |
| 38 | 36 | Il Divo | $9,727 | -24.8% | 23 | -6 | $422 | $264,251 | 6 | Delphi Filmverleih Produktion | false | false |
| 39 | 38 | Effi Briest | $9,446 | -19.9% | 56 | -11 | $168 | $3,314,400 | 15 | Constantin Film | false | false |
| 40 | 40 | Mesrine: Killer Instinct | $7,923 | +4.3% | 24 | -8 | $330 | $379,408 | 5 | Senator Film | false | false |
| 41 | 31 | Ricky | $7,634 | -73% | 45 | - | $169 | $45,991 | 2 | Concorde Filmverleih | false | false |
| 42 | 41 | Journey to the Center of the Earth | $7,183 | -1% | 15 | -3 | $478 | $1,486,420 | 12 | Warner Bros. | false | false |
| 43 | 34 | Defiance | $6,763 | -59.4% | 36 | -59 | $187 | $860,153 | 5 | Constantin Film | false | false |
| 44 | 37 | Männersache | $6,344 | -48.1% | 33 | -32 | $192 | $16,813,421 | 10 | Constantin Film | false | false |
