| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Angels & Demons | $677,769 | -46.4% | 142 | +1 | $4,773 | $2,599,540 | 2 | Sony Pictures Releasing | false | false |
| 2 | - | Night at the Museum: Battle of the Smithsonian | $402,049 | - | 107 | - | $3,757 | $544,813 | 1 | 20th Century Fox International | true | false |
| 3 | - | My Bloody Valentine | $126,859 | - | 25 | - | $5,074 | $164,587 | 1 | N/A | true | false |
| 4 | 2 | 17 Again | $114,729 | -37.6% | 52 | +1 | $2,206 | $402,276 | 2 | Warner Bros. | false | false |
| 5 | 3 | Star Trek | $83,126 | -52.2% | 73 | - | $1,138 | $977,222 | 3 | Universal Pictures International (UPI) | false | false |
| 6 | 4 | X-Men Origins: Wolverine | $45,572 | -51.6% | 77 | -20 | $591 | $1,412,493 | 4 | 20th Century Fox International | false | false |
| 7 | 5 | The Last House on the Left | $30,200 | -45.3% | 32 | - | $943 | $119,742 | 2 | Universal Pictures International (UPI) | false | false |
| 8 | - | Hannah Montana: The Movie | $24,208 | - | 76 | - | $318 | $25,934 | - | Walt Disney Pictures | - | false |
| 9 | - | Rachel Getting Married | $23,198 | - | 17 | - | $1,364 | $31,525 | 1 | Sony Pictures Releasing | true | false |
| 10 | 6 | Beverly Hills Chihuahua | $21,436 | -58.3% | 70 | -3 | $306 | $396,226 | 4 | Walt Disney Pictures | false | false |
| 11 | 8 | Slumdog Millionaire | $15,877 | -40.7% | 38 | -17 | $417 | $2,278,986 | 10 | Filmladen | false | false |
| 12 | 9 | The First Day of the Rest of Your Life | $13,557 | -44.1% | 15 | - | $903 | $100,348 | 3 | Polyfilm Verleih | false | false |
| 13 | 10 | Mid-August Lunch | $13,437 | -39.8% | 15 | - | $895 | $53,478 | 2 | Filmladen | false | false |
| 14 | 16 | Princess Lillifee | $8,921 | -34.6% | 48 | -2 | $185 | $488,491 | 9 | Constantin Film | false | false |
| 15 | 7 | Journey to the Center of the Earth | $8,702 | -69.4% | 45 | -9 | $193 | $247,458 | 4 | Warner Bros. | false | false |
| 16 | 11 | Duplicity | $8,521 | -61.7% | 28 | -20 | $304 | $352,501 | 4 | Universal Pictures International (UPI) | false | false |
| 17 | 12 | Monsters vs. Aliens | $8,422 | -61.9% | 38 | -6 | $221 | $925,281 | 8 | Universal Pictures International (UPI) | false | false |
| 18 | 14 | Paul Blart: Mall Cop | $7,934 | -53% | 34 | -2 | $233 | $2,279,015 | 9 | Sony Pictures Releasing | false | false |
| 19 | 17 | The Bone Man | $6,319 | -27.2% | 19 | -4 | $332 | $2,672,200 | 12 | Luna Filmverleih | false | false |
| 20 | 15 | I Love You, Man | $6,031 | -62.6% | 29 | -12 | $207 | $323,594 | 5 | Universal Pictures International (UPI) | false | false |
| 21 | 18 | Contact High | $5,487 | -31.4% | 15 | - | $365 | $195,729 | 6 | N/A | false | false |
| 22 | 26 | The Reader | $3,703 | +12.6% | 19 | - | $194 | $1,205,797 | 13 | Senator Film | false | false |
| 23 | 19 | The Duchess | $3,450 | -53% | 9 | -3 | $383 | $121,663 | 5 | Filmladen | false | false |
| 24 | 22 | I Saw the Sun 2009 Re-release | $2,634 | -51% | 4 | -3 | $658 | $166,415 | 6 | N/A | false | false |
| 25 | 33 | A Secret | $1,931 | +19.5% | 5 | +1 | $386 | $55,760 | 7 | Polyfilm Verleih | false | false |
| 26 | 31 | Gran Torino | $1,782 | +8.3% | 8 | - | $222 | $431,447 | 12 | Warner Bros. | false | false |
| 27 | 25 | The Three Investigators and the Secret of Terror Castle | $1,456 | -57.9% | 10 | -3 | $145 | $288,937 | 10 | Walt Disney Pictures | false | false |
| 28 | 24 | Let the Right One In | $1,301 | -66.5% | 7 | -5 | $185 | $33,465 | 4 | Filmladen | false | false |
| 29 | 27 | Lilly the Witch: The Dragon and the Magic Book | $1,065 | -60.2% | 14 | -4 | $76 | $1,444,361 | 14 | Walt Disney Pictures | false | false |
| 30 | 30 | Welcome to the Sticks | $1,030 | -46.9% | 6 | -3 | $171 | $1,296,988 | 28 | Luna Filmverleih | false | false |
| 31 | 29 | Wendy and Lucy | $966 | -51.6% | 1 | - | $966 | $13,853 | 3 | Stadtkino Filmverleih | false | false |
| 32 | - | Berlin Calling | $889 | - | 4 | - | $222 | $19,026 | 4 | Polyfilm Verleih | false | false |
| 33 | 28 | Race to Witch Mountain | $707 | -67.6% | 15 | -10 | $47 | $144,130 | 7 | Walt Disney Pictures | false | false |
| 34 | 34 | For My Father | $463 | -54.1% | 5 | - | $92 | $7,373 | 3 | Filmladen | false | false |
| 35 | - | Universalove | $446 | - | 2 | - | $223 | $50,094 | 6 | Stadtkino Filmverleih | false | false |
| 36 | - | Palermo Shooting | $389 | - | 6 | - | $64 | $14,316 | 5 | N/A | false | false |
| 37 | - | Gangster Girls | $251 | - | 2 | - | $125 | $30,850 | 9 | Stadtkino Filmverleih | false | false |
| 38 | 32 | Sturmfrei | $167 | -89.8% | 4 | -12 | $41 | $60,560 | 5 | Einhorn-Film | false | false |
| 39 | - | The Pink Panther 2 | $139 | - | 1 | - | $139 | $448,782 | 11 | Sony Pictures Releasing | false | false |
| 40 | - | Fay Grim | $136 | - | 1 | - | $136 | $4,069 | 1 | N/A | true | false |
