| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Crank: High Voltage | $42,910 | - | 7 | - | $6,130 | $42,910 | 1 | ACME | true | false |
| 2 | 1 | Fast & Furious | $26,589 | -30.1% | 10 | - | $2,658 | $287,539 | 3 | Universal Pictures International (UPI) | false | false |
| 3 | 3 | Monsters vs. Aliens | $19,542 | +8.9% | 8 | -2 | $2,442 | $119,763 | 3 | Universal Pictures International (UPI) | false | false |
| 4 | 4 | Confessions of a Shopaholic | $14,107 | -15.3% | 8 | - | $1,763 | $52,095 | 2 | Universal Pictures International (UPI) | false | false |
| 5 | 2 | Knowing | $13,392 | -30.2% | 7 | +1 | $1,913 | $52,303 | 2 | ACME | false | false |
| 6 | - | Race to Witch Mountain | $10,958 | - | 6 | - | $1,826 | $10,958 | 1 | Universal Pictures International (UPI) | true | false |
| 7 | 6 | Gran Torino | $2,665 | -1% | 2 | -1 | $1,332 | $32,679 | 4 | - | false | false |
| 8 | 5 | No Love in the City | $2,097 | -35.1% | 3 | -1 | $699 | $48,827 | 4 | MEED Films | false | false |
| 9 | 7 | Slumdog Millionaire | $1,953 | -15.7% | 1 | -1 | $1,953 | $273,628 | 10 | ACME | false | false |
| 10 | - | The Class | $1,300 | - | 3 | - | $433 | $17,646 | 1 | N/A | true | false |
| 11 | 9 | Bolt | $1,282 | -35.7% | 2 | -3 | $641 | $302,848 | 8 | Universal Pictures International (UPI) | false | false |
| 12 | 10 | The Wrestler | $932 | -50.9% | 1 | -1 | $932 | $12,985 | 3 | ACME | false | false |
| 13 | 12 | Hotel for Dogs | $251 | -67% | 3 | -3 | $83 | $45,197 | 5 | Universal Pictures International (UPI) | false | false |
| 14 | 19 | Involuntary | $243 | +237.5% | 1 | - | $243 | $4,110 | 3 | N/A | false | false |
| 15 | 21 | Beverly Hills Chihuahua | $194 | +259.3% | 1 | - | $194 | $124,325 | 11 | Universal Pictures International (UPI) | false | false |
| 16 | 14 | Watchmen | $171 | -47.5% | 1 | -1 | $171 | $50,859 | 6 | Universal Pictures International (UPI) | false | false |
| 17 | 11 | Marley & Me | $169 | -85.8% | 5 | -1 | $33 | $128,508 | 6 | Universal Pictures International (UPI) | false | false |
| 18 | 8 | Paul Blart: Mall Cop | $149 | -92.6% | 2 | -2 | $74 | $43,907 | 4 | Sony Pictures Releasing | false | false |
| 19 | - | Friday the 13th | $67 | - | 1 | - | $67 | $104,126 | 10 | Universal Pictures International (UPI) | false | false |
| 20 | 15 | The Crimson Wing: Mystery of the Flamingos | $62 | -66.3% | 1 | -1 | $62 | $20,898 | 6 | Universal Pictures International (UPI) | false | false |
| 21 | 16 | He's Just Not That Into You | $44 | -71.6% | 2 | -2 | $22 | $144,144 | 9 | - | false | false |
| 22 | 20 | Inkheart | $34 | -46.9% | 2 | - | $17 | $30,426 | 7 | - | false | false |
| 23 | - | Valkyrie | $10 | - | 1 | - | $10 | $74,445 | 9 | Universal Pictures International (UPI) | false | false |
| 24 | 13 | Duplicity | $6 | -98.9% | 1 | -2 | $6 | $47,039 | 5 | Universal Pictures International (UPI) | false | false |
