| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Knowing | $339,474 | - | 33 | - | $10,287 | $339,474 | 1 | Odeon | true | false |
| 2 | 1 | Slumdog Millionaire | $243,036 | -48.4% | 63 | -2 | $3,857 | $3,236,737 | 4 | Audio Visual Enterprises | false | false |
| 3 | - | Friday the 13th | $116,755 | - | 19 | - | $6,145 | $116,755 | 1 | United International Pictures | true | false |
| 4 | 2 | The International | $104,075 | -55.7% | 46 | -3 | $2,262 | $465,726 | 2 | Sony Pictures Releasing | false | false |
| 5 | - | The Edge of Love | $61,505 | - | 21 | - | $2,928 | $61,505 | 1 | Roadshow Films | true | false |
| 6 | 4 | Gran Torino | $57,664 | -44.3% | 26 | +2 | $2,217 | $1,076,131 | 5 | Roadshow Films | false | false |
| 7 | - | Stella | $41,729 | - | 2 | - | $20,864 | $41,729 | 1 | Rosebud | true | false |
| 8 | 9 | Bolt | $37,774 | -24.8% | 53 | +5 | $712 | $988,063 | 8 | Audio Visual Enterprises | false | false |
| 9 | 3 | Watchmen | $37,570 | -73.9% | 33 | -19 | $1,138 | $786,075 | 3 | United International Pictures | false | false |
| 10 | 5 | Race to Witch Mountain | $35,607 | -60.4% | 14 | -14 | $2,543 | $169,634 | 2 | Audio Visual Enterprises | false | false |
| 11 | 8 | Let the Right One In | $35,175 | -33.3% | 5 | - | $7,035 | $119,535 | 2 | Seven Films | false | false |
| 12 | 10 | The Tale of Despereaux | $33,366 | -30.1% | 26 | -1 | $1,283 | $346,022 | 5 | United International Pictures | false | false |
| 13 | 7 | Two Lovers | $28,743 | -58.7% | 15 | - | $1,916 | $319,771 | 3 | Odeon | false | false |
| 14 | 11 | The Reader | $25,296 | +0.1% | 14 | - | $1,806 | $1,633,587 | 12 | Odeon | false | false |
| 15 | - | Fugitive Pieces | $24,864 | - | 16 | - | $1,554 | $24,864 | 1 | Audio Visual Enterprises | true | false |
| 16 | 6 | Marley & Me | $20,201 | -73.1% | 19 | -18 | $1,063 | $730,545 | 4 | Odeon | false | false |
| 17 | 12 | Frozen River | $10,050 | -48.2% | 7 | - | $1,435 | $82,410 | 3 | PCV | false | false |
| 18 | 14 | The Visitor | $10,022 | -33.5% | 1 | - | $10,022 | $30,150 | 2 | - | false | false |
| 19 | 27 | Seven Pounds | $9,650 | +24,025% | 6 | +5 | $1,608 | $141,794 | 5 | Sony Pictures Releasing | false | false |
| 20 | 20 | The Dust of Time | $5,427 | -23.3% | 11 | -4 | $493 | $413,306 | 7 | Audio Visual Enterprises | false | false |
| 21 | 15 | The Pink Panther 2 | $5,031 | -64.9% | 10 | -4 | $503 | $1,819,141 | 7 | Sony Pictures Releasing | false | false |
| 22 | 18 | Milk | $2,904 | -61.4% | 3 | +1 | $968 | $454,274 | 11 | Odeon | false | false |
| 23 | - | The Snow-White Syndrome | $2,714 | - | 1 | - | $2,714 | $2,714 | 1 | N/A | true | false |
| 24 | 19 | He's Just Not That Into You | $1,326 | -81.5% | 10 | - | $132 | $611,002 | 6 | Village Films | false | false |
| 25 | 24 | Fly Me to the Moon 3D | $430 | -57.9% | 1 | -1 | $430 | $507,799 | 20 | Odeon | false | false |
