| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Slumdog Millionaire | $471,355 | -43.9% | 65 | -13 | $7,251 | $2,768,383 | 3 | Audio Visual Enterprises | false | false |
| 2 | - | The International | $234,694 | - | 49 | - | $4,789 | $234,694 | 1 | Sony Pictures Releasing | true | false |
| 3 | 2 | Watchmen | $144,017 | -67.3% | 52 | -12 | $2,769 | $692,043 | 2 | United International Pictures | false | false |
| 4 | 4 | Gran Torino | $103,515 | -32.5% | 24 | -2 | $4,313 | $1,041,180 | 4 | Roadshow Films | false | false |
| 5 | - | Race to Witch Mountain | $89,847 | - | 28 | - | $3,208 | $89,847 | 1 | Audio Visual Enterprises | true | false |
| 6 | 3 | Marley & Me | $74,993 | -63.4% | 37 | -3 | $2,026 | $670,436 | 3 | Odeon | false | false |
| 7 | 5 | Two Lovers | $69,636 | -54.5% | 15 | - | $4,642 | $255,149 | 2 | Odeon | false | false |
| 8 | - | Let the Right One In | $52,742 | - | 5 | - | $10,548 | $52,742 | 1 | Seven Films | true | false |
| 9 | 6 | Bolt | $50,260 | -27.7% | 48 | -14 | $1,047 | $930,469 | 7 | Audio Visual Enterprises | false | false |
| 10 | 9 | The Tale of Despereaux | $47,738 | -22.5% | 27 | -1 | $1,768 | $295,269 | 4 | United International Pictures | false | false |
| 11 | 11 | The Reader | $25,269 | -38.6% | 14 | - | $1,804 | $1,434,633 | 11 | Odeon | false | false |
| 12 | 13 | Frozen River | $19,397 | -45.5% | 7 | -1 | $2,771 | $62,712 | 2 | PCV | false | false |
| 13 | 7 | Eden Is West | $17,336 | -74% | 11 | -9 | $1,576 | $633,532 | 5 | Odeon | false | false |
| 14 | - | The Visitor | $15,075 | - | 1 | - | $15,075 | $15,075 | 1 | - | true | false |
| 15 | 12 | The Pink Panther 2 | $14,329 | -63.6% | 14 | -15 | $1,023 | $1,808,465 | 6 | Sony Pictures Releasing | false | false |
| 16 | 14 | The Unborn | $10,494 | -65.1% | 12 | -3 | $874 | $393,992 | 5 | United International Pictures | false | false |
| 17 | 22 | Madagascar: Escape 2 Africa | $8,756 | -16.3% | 10 | -3 | $875 | $3,322,522 | 14 | United International Pictures | false | false |
| 18 | 24 | Milk | $7,525 | -9.7% | 2 | -5 | $3,762 | $451,370 | 10 | Odeon | false | false |
| 19 | 19 | He's Just Not That Into You | $7,167 | -56.4% | 10 | - | $716 | $603,435 | 5 | Village Films | false | false |
| 20 | 18 | The Dust of Time | $7,075 | -57.4% | 15 | -2 | $471 | $403,930 | 6 | Audio Visual Enterprises | false | false |
| 21 | 15 | Valkyrie | $5,799 | -80.4% | 5 | -13 | $1,159 | $770,132 | 5 | Odeon | false | false |
| 22 | 8 | What Just Happened | $4,020 | -93.9% | 10 | -6 | $402 | $86,430 | 2 | Village Films | false | false |
| 23 | - | Angel and the Weightlifter | $3,518 | - | 1 | - | $3,518 | $3,518 | 1 | - | true | false |
| 24 | 27 | Fly Me to the Moon 3D | $1,021 | -50.1% | 2 | -2 | $510 | $506,476 | 19 | Odeon | false | false |
| 25 | 30 | Rachel Getting Married | $372 | +5.7% | 1 | -1 | $372 | $56,790 | 5 | Audio Visual Enterprises | false | false |
| 26 | 28 | Underworld: Rise of the Lycans | $231 | -72.3% | 1 | -3 | $231 | $1,226,172 | 9 | Audio Visual Enterprises | false | false |
| 27 | 29 | Seven Pounds | $40 | -93.9% | 1 | -1 | $40 | $132,139 | 4 | Sony Pictures Releasing | false | false |
