| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Duplicity | $278,545 | - | 37 | - | $7,528 | $288,235 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | 1 | Coco | $190,707 | -36.9% | 21 | - | $9,081 | $538,976 | 2 | Universal Pictures International (UPI) | false | false |
| 3 | 2 | Marley & Me | $156,603 | -15.3% | 50 | - | $3,132 | $763,501 | 3 | 20th Century Fox International | false | false |
| 4 | 3 | Confessions of a Shopaholic | $153,428 | -10.7% | 52 | - | $2,950 | $461,905 | 2 | Walt Disney Pictures | false | false |
| 5 | 4 | Slumdog Millionaire | $151,567 | -4.6% | 39 | - | $3,886 | $2,546,078 | 11 | Cinéart | false | false |
| 6 | 5 | S&M Judge | $140,512 | +1% | 19 | - | $7,395 | $496,080 | 3 | Kinepolis Film Distribution (KFD) | false | false |
| 7 | - | Red Cliff | $110,310 | - | 23 | - | $4,796 | $112,047 | 1 | Belga Films | true | false |
| 8 | - | District 13: Ultimatum | $105,114 | - | 13 | - | $8,085 | $112,419 | 1 | Belga Films | true | false |
| 9 | 12 | Bolt | $96,575 | +39% | 74 | -6 | $1,305 | $2,695,888 | 7 | Walt Disney Pictures | false | false |
| 10 | 6 | Watchmen | $92,872 | -27.9% | 47 | -4 | $1,976 | $1,023,507 | 4 | Universal Pictures International (UPI) | false | false |
| 11 | 7 | Gran Torino | $77,674 | -9.8% | 25 | -2 | $3,106 | $834,490 | 5 | Warner Bros. | false | false |
| 12 | 13 | Hotel for Dogs | $68,149 | +40.9% | 36 | -1 | $1,893 | $1,032,949 | 6 | Universal Pictures International (UPI) | false | false |
| 13 | 8 | The Unborn | $65,100 | -21.8% | 17 | - | $3,829 | $1,032,939 | 2 | Universal Pictures International (UPI) | false | false |
| 14 | 9 | The Reader | $63,605 | -13.1% | 25 | +1 | $2,544 | $552,502 | 4 | Benelux Film Distributors | false | false |
| 15 | 11 | The Curious Case of Benjamin Button | $51,445 | -26.2% | 42 | -8 | $1,224 | $3,041,763 | 8 | Warner Bros. | false | false |
| 16 | 10 | The International | $44,988 | -36.6% | 30 | - | $1,499 | $299,202 | 3 | Sony Pictures Releasing | false | false |
| 17 | - | Welcome | $35,481 | - | 11 | - | $3,225 | $43,462 | 1 | Cinéart | true | false |
| 18 | 16 | Milk | $25,604 | -2.6% | 15 | +2 | $1,706 | $278,969 | 5 | A-Film Distribution | false | false |
| 19 | 14 | The Burning Plain | $24,966 | -25.7% | 13 | - | $1,920 | $71,245 | 2 | Cinéart | false | false |
| 20 | 15 | Underworld: Rise of the Lycans | $22,706 | -15.7% | 5 | - | $4,541 | $54,577 | 2 | Sony Pictures Releasing | false | false |
| 21 | 17 | LOL (Laughing Out Loud) | $20,788 | -13.6% | 21 | - | $989 | $1,020,280 | 8 | Alternative Films | false | false |
| 22 | 20 | The Tale of Despereaux | $20,662 | +31.3% | 31 | - | $666 | $367,066 | 5 | Universal Pictures International (UPI) | false | false |
| 23 | 22 | Loft | $12,529 | +0.9% | 19 | - | $659 | $9,661,022 | 23 | Independent Films | false | false |
| 24 | 23 | Le code a changé | $11,655 | +5% | 17 | +2 | $685 | $485,251 | 6 | Universal Pictures International (UPI) | false | false |
| 25 | 18 | Defiance | $11,574 | -42.8% | 12 | -12 | $964 | $198,618 | 4 | Kinepolis Film Distribution (KFD) | false | false |
| 26 | 19 | The Girl on the Train | $10,885 | -32.4% | 12 | +2 | $907 | $37,441 | 2 | Benelux Film Distributors | false | false |
| 27 | 24 | Seraphine | $10,153 | -8.5% | 9 | - | $1,128 | $242,889 | 23 | Cinéart | false | false |
| 28 | 37 | Madagascar: Escape 2 Africa | $8,016 | +82.2% | 9 | -6 | $890 | $6,231,275 | 17 | Universal Pictures International (UPI) | false | false |
| 29 | 21 | Push | $7,411 | -50.3% | 4 | -5 | $1,852 | $135,525 | 4 | Belga Films | false | false |
| 30 | - | What Just Happened | $5,963 | - | 6 | - | $993 | $12,437 | 1 | Paradiso Entertainment | true | false |
| 31 | 38 | Twilight | $5,358 | +33% | 9 | - | $595 | $3,157,902 | 18 | Belga Films | false | false |
| 32 | 34 | The Three Investigators and the Secret of Skeleton Island 2009 Re-release | $5,353 | +4.9% | 5 | - | $1,070 | $10,813 | 2 | Walt Disney Pictures | false | false |
| 33 | 27 | All About Actresses | $5,207 | -23.9% | 3 | -1 | $1,735 | $29,264 | 3 | N/A | false | false |
| 34 | 35 | The Beaches of Agnès | $5,048 | <0.1% | 2 | - | $2,524 | $28,874 | 3 | Cinéart | false | false |
| 35 | 31 | Last Chance Harvey | $4,839 | -13.6% | 2 | - | $2,419 | $134,736 | 4 | Kinepolis Film Distribution (KFD) | false | false |
| 36 | - | Princess Lillifee | $3,995 | - | 4 | - | $998 | $3,995 | 1 | Walt Disney Pictures | true | false |
| 37 | 29 | The Pink Panther 2 | $3,226 | -48.7% | 5 | -13 | $645 | $454,561 | 6 | Sony Pictures Releasing | false | false |
| 38 | - | 24 City | $3,004 | - | 1 | - | $3,004 | $3,004 | 1 | Cinéart | true | false |
| 39 | 32 | Zack and Miri Make a Porno | $2,850 | -48.6% | 4 | -12 | $712 | $270,354 | 6 | Benelux Film Distributors | false | false |
| 40 | 26 | Cyprien | $2,527 | -68.4% | 4 | -5 | $631 | $208,733 | 5 | N/A | false | false |
| 41 | 43 | Friday the 13th | $2,495 | +15.7% | 4 | -3 | $623 | $413,600 | 7 | Universal Pictures International (UPI) | false | false |
| 42 | 28 | Ultimate Heist | $2,216 | -65.3% | 4 | - | $554 | $9,856 | 2 | Centre national du cinéma et de l'image animée (CNC) | false | false |
| 43 | 57 | Welcome to the Sticks | $2,158 | +357.2% | 3 | +2 | $719 | $10,746,995 | 57 | Alternative Films | false | false |
| 44 | - | Leonera | $1,952 | - | 4 | - | $488 | $2,638 | 1 | A-Film Distribution | true | false |
| 45 | 46 | Doubt | $1,938 | +22.3% | 7 | -4 | $276 | $305,023 | 7 | Walt Disney Pictures | false | false |
| 46 | 44 | Tulpan | $1,696 | -14.4% | 6 | - | $282 | $13,265 | 4 | Benelux Film Distributors | false | false |
| 47 | 49 | The Fall | $1,650 | +22% | 3 | - | $550 | $7,074 | 3 | Paradiso Entertainment | false | false |
| 48 | 42 | Lilly the Witch: The Dragon and the Magic Book | $1,618 | -29.9% | 5 | - | $323 | $46,153 | 6 | Kinepolis Film Distribution (KFD) | false | false |
| 49 | 50 | Delta | $1,584 | +23.8% | 3 | +1 | $528 | $6,208 | 3 | Benelux Film Distributors | false | false |
| 50 | 48 | The Secret of Moonacre | $1,552 | +11.7% | 5 | -3 | $310 | $66,205 | 6 | Kinepolis Film Distribution (KFD) | false | false |
| 51 | 52 | The Secret of Kells | $1,547 | +44.2% | 8 | - | $193 | $39,487 | 7 | Kinepolis Film Distribution (KFD) | false | false |
| 52 | 60 | Moscow, Belgium | $1,509 | +1,136.9% | 2 | - | $754 | $1,897,442 | 61 | Kinepolis Film Distribution (KFD) | false | false |
| 53 | - | Laban the Little Ghost 2009 Re-release | $1,409 | - | 2 | - | $704 | $2,152 | 1 | Jekino | true | false |
| 54 | 45 | New in Town | $1,160 | -30.5% | 1 | - | $1,160 | $118,701 | 5 | Kinepolis Film Distribution (KFD) | false | false |
| 55 | 30 | Bride Wars | $918 | -85.2% | 3 | -14 | $306 | $1,010,104 | 7 | 20th Century Fox International | false | false |
| 56 | 55 | The Baader Meinhof Complex | $859 | +27.8% | 4 | +2 | $214 | $31,710 | 9 | A-Film Distribution | false | false |
| 57 | 54 | Mia and the Migoo | $801 | +9% | 3 | -2 | $267 | $13,434 | 6 | Benelux Film Distributors | false | false |
| 58 | 25 | Valkyrie | $790 | -92.3% | 6 | -14 | $131 | $1,926,066 | 9 | 20th Century Fox International | false | false |
| 59 | 53 | City of Ember | $784 | +4.4% | 1 | - | $784 | $159,413 | 6 | Belga Films | false | false |
| 60 | 47 | Revolutionary Road | $726 | -51.7% | 6 | -2 | $121 | $1,017,408 | 10 | Universal Pictures International (UPI) | false | false |
| 61 | 56 | Dirty Mind | $557 | +0.2% | 3 | +1 | $185 | $194,010 | 9 | Kinepolis Film Distribution (KFD) | false | false |
| 62 | - | Youssou Ndour: I Bring What I Love | $348 | - | 2 | - | $174 | $558 | 1 | ABC Distribution | true | false |
| 63 | 41 | Modern Life | $140 | -94.1% | 1 | -1 | $140 | $58,184 | 21 | Benelux Film Distributors | false | false |
