| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Coco | $302,367 | - | 21 | - | $14,398 | $311,093 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | 1 | Marley & Me | $184,959 | -43.6% | 50 | - | $3,699 | $587,495 | 2 | 20th Century Fox International | false | false |
| 3 | - | Confessions of a Shopaholic | $171,727 | - | 52 | - | $3,302 | $282,830 | 1 | Walt Disney Pictures | true | false |
| 4 | 3 | Slumdog Millionaire | $158,842 | -26.8% | 39 | +2 | $4,072 | $2,356,341 | 10 | Cinéart | false | false |
| 5 | 4 | S&M Judge | $139,067 | -15.3% | 19 | - | $7,319 | $331,097 | 2 | Kinepolis Film Distribution (KFD) | false | false |
| 6 | 2 | Watchmen | $128,879 | -45.2% | 51 | -1 | $2,527 | $912,284 | 3 | Universal Pictures International (UPI) | false | false |
| 7 | 8 | Gran Torino | $86,083 | -27.6% | 27 | -3 | $3,188 | $740,632 | 4 | Warner Bros. | false | false |
| 8 | - | The Unborn | $83,211 | - | 17 | - | $4,894 | $100,130 | 1 | Universal Pictures International (UPI) | true | false |
| 9 | 9 | The Reader | $73,197 | -38.3% | 24 | - | $3,049 | $465,725 | 3 | Benelux Film Distributors | false | false |
| 10 | 5 | The International | $70,918 | -46.8% | 30 | - | $2,363 | $241,753 | 2 | Sony Pictures Releasing | false | false |
| 11 | 6 | The Curious Case of Benjamin Button | $69,701 | -45.6% | 50 | - | $1,394 | $2,982,706 | 7 | Warner Bros. | false | false |
| 12 | 7 | Bolt | $69,472 | -43.5% | 80 | -9 | $868 | $2,596,225 | 6 | Walt Disney Pictures | false | false |
| 13 | 10 | Hotel for Dogs | $48,351 | -35% | 37 | -1 | $1,306 | $962,406 | 5 | Universal Pictures International (UPI) | false | false |
| 14 | - | The Burning Plain | $33,613 | - | 13 | - | $2,585 | $37,032 | 1 | Cinéart | true | false |
| 15 | - | Underworld: Rise of the Lycans | $26,942 | - | 5 | - | $5,388 | $26,942 | 1 | Sony Pictures Releasing | true | false |
| 16 | 13 | Milk | $26,287 | -34.2% | 13 | - | $2,022 | $243,959 | 4 | A-Film Distribution | false | false |
| 17 | 11 | LOL (Laughing Out Loud) | $24,048 | -61.7% | 21 | -2 | $1,145 | $996,351 | 7 | Alternative Films | false | false |
| 18 | 12 | Defiance | $20,250 | -50% | 24 | -5 | $843 | $183,964 | 3 | Kinepolis Film Distribution (KFD) | false | false |
| 19 | - | The Girl on the Train | $16,093 | - | 10 | - | $1,609 | $21,274 | 1 | Benelux Film Distributors | true | false |
| 20 | 16 | The Tale of Despereaux | $15,740 | -43.2% | 31 | -6 | $507 | $346,230 | 4 | Universal Pictures International (UPI) | false | false |
| 21 | 14 | Push | $14,920 | -58% | 9 | - | $1,657 | $125,284 | 3 | Belga Films | false | false |
| 22 | 20 | Loft | $12,414 | -41.3% | 19 | -3 | $653 | $9,630,422 | 22 | Independent Films | false | false |
| 23 | 15 | Le code a changé | $11,099 | -61.4% | 15 | -3 | $739 | $470,547 | 5 | Universal Pictures International (UPI) | false | false |
| 24 | 22 | Seraphine | $11,092 | -23.5% | 9 | - | $1,232 | $228,955 | 22 | Cinéart | false | false |
| 25 | 19 | Valkyrie | $10,243 | -54.3% | 20 | -10 | $512 | $1,920,223 | 8 | 20th Century Fox International | false | false |
| 26 | 18 | Cyprien | $7,996 | -68.3% | 9 | -7 | $888 | $205,170 | 4 | N/A | false | false |
| 27 | 25 | All About Actresses | $6,842 | -35.8% | 4 | -3 | $1,710 | $21,427 | 2 | N/A | false | false |
| 28 | - | Ultimate Heist | $6,386 | - | 4 | - | $1,596 | $6,386 | 1 | Centre national du cinéma et de l'image animée (CNC) | true | false |
| 29 | 21 | The Pink Panther 2 | $6,290 | -68.4% | 18 | -6 | $349 | $446,370 | 5 | Sony Pictures Releasing | false | false |
| 30 | 17 | Bride Wars | $6,202 | -76.6% | 17 | -8 | $364 | $1,005,408 | 6 | 20th Century Fox International | false | false |
| 31 | 26 | Last Chance Harvey | $5,598 | -45% | 2 | -6 | $2,799 | $126,020 | 3 | Kinepolis Film Distribution (KFD) | false | false |
| 32 | 23 | Zack and Miri Make a Porno | $5,543 | -57.8% | 16 | - | $346 | $266,860 | 5 | Benelux Film Distributors | false | false |
| 33 | 27 | Spy(Ies) | $5,154 | -48.9% | 4 | -3 | $1,288 | $44,292 | 3 | N/A | false | false |
| 34 | - | The Three Investigators and the Secret of Skeleton Island 2009 Re-release | $5,104 | - | 5 | - | $1,020 | $5,104 | 1 | Walt Disney Pictures | true | false |
| 35 | 31 | The Beaches of Agnès | $5,045 | -32.3% | 2 | - | $2,522 | $22,200 | 2 | Cinéart | false | false |
| 36 | 28 | Boy A | $4,624 | -51.6% | 7 | -1 | $660 | $18,087 | 2 | ABC Distribution | false | false |
| 37 | 35 | Madagascar: Escape 2 Africa | $4,399 | -28.8% | 15 | - | $293 | $6,223,195 | 16 | Universal Pictures International (UPI) | false | false |
| 38 | 24 | Twilight | $4,030 | -62.2% | 9 | -12 | $447 | $3,152,029 | 17 | Belga Films | false | false |
| 39 | - | Three Monkeys | $3,561 | - | 5 | - | $712 | $3,827 | 1 | N/A | true | false |
| 40 | 30 | Ricky | $3,357 | -55.7% | 8 | -2 | $419 | $28,645 | 3 | Cinéart | false | false |
| 41 | 55 | Modern Life | $2,382 | +1,062% | 2 | - | $1,191 | $57,227 | 20 | Benelux Film Distributors | false | false |
| 42 | 32 | Lilly the Witch: The Dragon and the Magic Book | $2,309 | -67% | 5 | - | $461 | $44,413 | 5 | Kinepolis Film Distribution (KFD) | false | false |
| 43 | 29 | Friday the 13th | $2,156 | -76.4% | 7 | -7 | $308 | $403,203 | 6 | Universal Pictures International (UPI) | false | false |
| 44 | 42 | Tulpan | $1,982 | -19.1% | 6 | - | $330 | $11,572 | 3 | Benelux Film Distributors | false | false |
| 45 | 38 | New in Town | $1,670 | -67.2% | 1 | -6 | $1,670 | $116,008 | 4 | Kinepolis Film Distribution (KFD) | false | false |
| 46 | 33 | Doubt | $1,585 | -77.3% | 11 | -1 | $144 | $301,199 | 6 | Walt Disney Pictures | false | false |
| 47 | 40 | Revolutionary Road | $1,503 | -55.9% | 8 | -6 | $187 | $990,074 | 9 | Universal Pictures International (UPI) | false | false |
| 48 | 41 | The Secret of Moonacre | $1,390 | -50% | 8 | +1 | $173 | $64,264 | 5 | Kinepolis Film Distribution (KFD) | false | false |
| 49 | 45 | The Fall | $1,353 | -16.7% | 3 | - | $451 | $5,006 | 2 | Paradiso Entertainment | false | false |
| 50 | 47 | Delta | $1,280 | +9.2% | 2 | - | $640 | $4,196 | 2 | Benelux Film Distributors | false | false |
| 51 | - | Snow | $1,211 | - | 4 | - | $302 | $2,274 | 1 | N/A | true | false |
| 52 | 49 | The Secret of Kells | $1,073 | +2.2% | 8 | +1 | $134 | $36,808 | 6 | Kinepolis Film Distribution (KFD) | false | false |
| 53 | 37 | City of Ember | $751 | -85.5% | 1 | -8 | $751 | $158,628 | 5 | Belga Films | false | false |
| 54 | 52 | Mia and the Migoo | $735 | - | 5 | - | $147 | $12,633 | 5 | Benelux Film Distributors | false | false |
| 55 | 44 | The Baader Meinhof Complex | $672 | -64.8% | 2 | -2 | $336 | $30,771 | 8 | A-Film Distribution | false | false |
| 56 | 51 | Dirty Mind | $556 | -34.4% | 2 | - | $278 | $193,353 | 8 | Kinepolis Film Distribution (KFD) | false | false |
| 57 | 43 | Welcome to the Sticks | $472 | -77.8% | 1 | -3 | $472 | $10,743,995 | 56 | Alternative Films | false | false |
| 58 | 57 | Elegy | $283 | +49.7% | 2 | - | $141 | $181,282 | 22 | Kinepolis Film Distribution (KFD) | false | false |
| 59 | - | Blood Brothers | $157 | - | 3 | - | $52 | $1,298 | 1 | Paradiso Entertainment | true | false |
| 60 | 54 | Moscow, Belgium | $122 | -46% | 2 | - | $61 | $1,894,455 | 60 | Kinepolis Film Distribution (KFD) | false | false |
