| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | He's Just Not That Into You | $31,098 | - | 6 | - | $5,183 | $51,992 | 1 | - | true | false |
| 2 | - | Valkyrie | $26,789 | - | 7 | - | $3,827 | $26,789 | 1 | Universal Pictures International (UPI) | true | false |
| 3 | - | The Pink Panther 2 | $23,847 | - | 7 | - | $3,406 | $32,643 | 1 | ACME | true | false |
| 4 | 7 | Slumdog Millionaire | $21,024 | +35.7% | 2 | - | $10,512 | $51,706 | 2 | ACME | false | false |
| 5 | 2 | The Curious Case of Benjamin Button | $16,446 | -60.9% | 6 | - | $2,741 | $148,462 | 3 | Garsu Pasaulio Irasai | false | false |
| 6 | 1 | Friday the 13th | $12,695 | -76.8% | 7 | - | $1,813 | $82,296 | 2 | Universal Pictures International (UPI) | false | false |
| 7 | 4 | Yes Man | $10,026 | -51.2% | 7 | - | $1,432 | $454,714 | 7 | Garsu Pasaulio Irasai | false | false |
| 8 | 3 | Beverly Hills Chihuahua | $7,883 | -71.5% | 7 | - | $1,126 | $113,676 | 3 | Universal Pictures International (UPI) | false | false |
| 9 | 8 | Fly Me to the Moon 3D | $4,326 | -54.8% | 1 | - | $4,326 | $110,364 | 5 | Universal Pictures International (UPI) | false | false |
| 10 | 5 | The Return of the Musketeers, or The Treasures of Cardinal Mazarin | $3,636 | -82.2% | 6 | - | $606 | $68,297 | 3 | ACME | false | false |
| 11 | 13 | U2 3D | $1,709 | -46.3% | 1 | - | $1,709 | $53,162 | 5 | Universal Pictures International (UPI) | false | false |
| 12 | 11 | Underworld: Rise of the Lycans | $1,178 | -74.2% | 4 | -2 | $294 | $76,182 | 4 | ACME | false | false |
| 13 | 12 | The Tale of Despereaux | $1,130 | -74.4% | 4 | -1 | $282 | $252,626 | 9 | Universal Pictures International (UPI) | false | false |
| 14 | 9 | Revolutionary Road | $995 | -85.8% | 2 | -2 | $497 | $48,385 | 4 | Universal Pictures International (UPI) | false | false |
| 15 | - | The Bug Trainer | $822 | - | - | - | - | $822 | 1 | N/A | true | false |
| 16 | 10 | Changeling | $707 | -86.5% | 1 | -3 | $707 | $67,589 | 5 | Universal Pictures International (UPI) | false | false |
| 17 | 19 | Madagascar: Escape 2 Africa | $317 | -58.9% | 1 | -1 | $317 | $687,877 | 13 | Universal Pictures International (UPI) | false | false |
| 18 | - | RocknRolla | $223 | - | 5 | - | $44 | $63,585 | 6 | Garsu Pasaulio Irasai | false | false |
| 19 | 16 | Bride Wars | $134 | -87.5% | 2 | +1 | $67 | $140,193 | 6 | Universal Pictures International (UPI) | false | false |
| 20 | 17 | Frost/Nixon | $40 | -95.6% | 1 | - | $40 | $1,395 | 2 | Universal Pictures International (UPI) | false | false |
