| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | He's Just Not That Into You | $27,465,000 | $27,785,487 | +$320,487 | +1.2% | 3,175 | $27,465,000 | $27,785,487 | 1 | Warner Bros. | - |
| 2 | 2 | - | Taken | $20,300,000 | $20,547,346 | +$247,346 | +1.2% | 3,184 | $53,364,000 | $53,610,944 | 2 | Twentieth Century Fox | - |
| 3 | 3 | - | Coraline | $16,335,000 | $16,849,640 | +$514,640 | +3.2% | 2,299 | $16,335,000 | $16,849,640 | 1 | Focus Features | - |
| 4 | 4 | - | The Pink Panther 2 | $12,000,000 | $11,588,150 | -$411,850 | -3.4% | 3,243 | $12,000,000 | $11,588,150 | 1 | Sony Pictures Releasing | - |
| 5 | 5 | - | Paul Blart: Mall Cop | $11,000,000 | $10,884,825 | -$115,175 | -1% | 3,169 | $97,002,000 | $96,886,687 | 4 | Sony Pictures Releasing | - |
| 6 | 6 | - | Push | $10,204,000 | $10,079,109 | -$124,891 | -1.2% | 2,313 | $10,204,000 | $10,079,109 | 1 | Summit Entertainment | - |
| 7 | 8 | +1 | Gran Torino | $7,420,000 | $7,155,339 | -$264,661 | -3.6% | 2,705 | $120,280,000 | $120,195,197 | 9 | Warner Bros. | - |
| 8 | 7 | -1 | Slumdog Millionaire | $7,400,000 | $7,177,270 | -$222,730 | -3% | 1,724 | $77,426,000 | $77,203,055 | 13 | Fox Searchlight Pictures | - |
| 9 | 9 | - | The Uninvited | $6,400,000 | $6,262,651 | -$137,349 | -2.1% | 2,344 | $18,379,000 | $18,242,141 | 2 | DreamWorks | - |
| 10 | 10 | - | Hotel for Dogs | $5,820,000 | $5,711,229 | -$108,771 | -1.9% | 2,734 | $55,234,000 | $55,125,062 | 4 | DreamWorks | - |
| 11 | 11 | - | Underworld: Rise of the Lycans | $3,900,000 | $4,083,369 | +$183,369 | +4.7% | 2,042 | $39,659,000 | $39,841,908 | 3 | Screen Gems | - |
| 12 | 12 | - | New in Town | $3,300,000 | $3,228,190 | -$71,810 | -2.2% | 1,941 | $11,928,000 | $11,856,481 | 2 | Lionsgate | - |
| 13 | 13 | - | The Curious Case of Benjamin Button | $2,400,000 | $2,302,188 | -$97,812 | -4.1% | 1,478 | $120,048,000 | $119,950,285 | 7 | Paramount Pictures | - |
| 14 | 14 | - | The Reader | $2,300,000 | $2,275,489 | -$24,511 | -1.1% | 862 | $16,058,000 | $16,033,070 | 9 | The Weinstein Company | - |
| 15 | 15 | - | The Wrestler | $2,230,000 | $2,207,555 | -$22,445 | -1% | 754 | $16,193,000 | $16,170,788 | 8 | Fox Searchlight Pictures | - |
| 16 | 16 | - | My Bloody Valentine | $1,850,000 | $1,856,829 | +$6,829 | +0.4% | 671 | $48,176,000 | $48,182,383 | 4 | Lionsgate | - |
| 17 | 17 | - | Revolutionary Road | $1,680,000 | $1,670,594 | -$9,406 | -0.6% | 935 | $18,748,000 | $18,738,643 | 7 | Paramount Vantage | - |
| 18 | 18 | - | Bride Wars | $1,500,000 | $1,500,029 | +$29 | <0.1% | 1,097 | $56,244,000 | $56,244,349 | 5 | Twentieth Century Fox | - |
| 19 | 19 | - | Defiance | $1,420,000 | $1,393,322 | -$26,678 | -1.9% | 858 | $25,224,000 | $25,196,967 | 6 | Paramount Vantage | - |
| 20 | 20 | - | Inkheart | $1,150,000 | $1,231,458 | +$81,458 | +7.1% | 1,175 | $14,805,000 | $14,885,535 | 3 | Warner Bros. | - |
| 21 | 21 | - | Milk | $1,102,000 | $1,125,312 | +$23,312 | +2.1% | 601 | $25,255,000 | $25,257,922 | 11 | Focus Features | - |
| 22 | 22 | - | Frost/Nixon | $753,000 | $771,985 | +$18,985 | +2.5% | 478 | $15,632,000 | $15,651,111 | 10 | Universal Pictures | - |
| 23 | 23 | - | Doubt | $729,000 | $722,534 | -$6,466 | -0.9% | 401 | $29,110,000 | $29,103,495 | 9 | Miramax | - |
| 24 | 24 | - | Notorious | $630,000 | $628,621 | -$1,379 | -0.2% | 440 | $36,216,000 | $36,214,659 | 4 | Fox Searchlight Pictures | - |
| 25 | 25 | - | Last Chance Harvey | $580,000 | $576,363 | -$3,637 | -0.6% | 448 | $12,800,000 | $12,796,195 | 7 | Overture Films | - |
| 26 | 26 | - | Twilight | $469,000 | $480,388 | +$11,388 | +2.4% | 326 | $187,737,000 | $187,748,420 | 12 | Summit Entertainment | - |
| 27 | 27 | - | Marley & Me | $460,000 | $455,301 | -$4,699 | -1% | 450 | $140,554,000 | $140,548,943 | 7 | Twentieth Century Fox | - |
| 28 | 28 | - | The Unborn | $386,000 | $393,830 | +$7,830 | +2% | 388 | $41,998,000 | $42,005,890 | 5 | Universal Pictures | - |
| 29 | 29 | - | Yes Man | $360,000 | $368,295 | +$8,295 | +2.3% | 345 | $96,294,000 | $96,302,759 | 8 | Warner Bros. | - |
| 30 | 31 | +1 | Madagascar: Escape 2 Africa | $255,000 | $247,079 | -$7,921 | -3.1% | 240 | $179,615,000 | $179,606,381 | 14 | DreamWorks | - |
| 31 | 33 | +2 | The Tale of Despereaux | $236,000 | $223,560 | -$12,440 | -5.3% | 276 | $50,189,000 | $50,176,530 | 8 | Universal Pictures | - |
| 32 | 34 | +2 | Valkyrie | $204,000 | $206,382 | +$2,382 | +1.2% | 258 | $82,017,000 | $82,019,420 | 7 | United Artists | - |
| 33 | 36 | +3 | The Class | $192,000 | $180,590 | -$11,410 | -5.9% | 27 | $588,000 | $575,846 | 8 | Sony Pictures Classics | - |
| 34 | 37 | +3 | Fanboys | $164,000 | $171,533 | +$7,533 | +4.6% | 44 | $164,000 | $171,533 | 1 | The Weinstein Company | - |
| 35 | 40 | +5 | Waltz with Bashir | $146,000 | $137,749 | -$8,251 | -5.7% | 46 | $1,208,000 | $1,216,131 | 7 | Sony Pictures Classics | - |
| 36 | 41 | +5 | Rachel Getting Married | $143,000 | $133,042 | -$9,958 | -7% | 95 | $11,903,000 | $11,892,890 | 19 | Sony Pictures Classics | - |
| 37 | 46 | +9 | Wendy and Lucy | $48,500 | $44,501 | -$3,999 | -8.2% | 20 | $313,000 | $309,349 | 9 | Oscilloscope | - |
| 38 | 58 | +20 | Vicky Cristina Barcelona | $18,200 | $17,743 | -$457 | -2.5% | 15 | $23,192,000 | $23,191,990 | 26 | Metro-Goldwyn-Mayer (MGM) | - |
| 39 | 77 | +38 | Outlander | $2,500 | $2,495 | -$5 | -0.2% | 15 | $105,000 | $105,307 | 3 | Third Rail Releasing | - |
