| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Underworld: Rise of the Lycans | $176,780 | -48.9% | 40 | - | $4,419 | $1,133,251 | 3 | N/A | false | false |
| 2 | - | Marley & Me | $127,284 | - | 34 | - | $3,743 | $127,284 | 1 | N/A | true | false |
| 3 | 2 | Inkheart | $72,597 | -54.4% | 37 | - | $1,962 | $258,948 | 2 | N/A | false | false |
| 4 | 4 | Status: Single | $63,068 | -49% | 50 | - | $1,261 | $208,008 | 2 | N/A | false | false |
| 5 | - | Seven Pounds | $59,055 | - | 25 | - | $2,362 | $59,055 | 1 | N/A | true | false |
| 6 | 5 | Love Me Again (Land Down Under) | $55,905 | -38.9% | 50 | -10 | $1,118 | $1,385,591 | 4 | N/A | false | false |
| 7 | - | My Bloody Valentine | $44,369 | - | 14 | - | $3,169 | $44,369 | 1 | N/A | true | false |
| 8 | 3 | Beverly Hills Chihuahua | $40,113 | -73.5% | 36 | -39 | $1,114 | $214,369 | 2 | N/A | false | false |
| 9 | 6 | Australia | $35,413 | -60.9% | 25 | -15 | $1,416 | $145,562 | 2 | N/A | false | false |
| 10 | 7 | Yes Man | $28,816 | -51.3% | 22 | -1 | $1,309 | $275,416 | 3 | N/A | false | false |
| 11 | 11 | Bride Wars | $23,280 | +181.3% | 22 | +12 | $1,058 | $308,579 | 4 | N/A | false | false |
| 12 | 8 | The Curious Case of Benjamin Button | $19,297 | -43.3% | 23 | -2 | $839 | $735,756 | 5 | N/A | false | false |
| 13 | - | Doubt | $14,194 | - | 5 | - | $2,838 | $14,194 | 1 | N/A | true | false |
| 14 | - | Milk | $12,690 | - | 10 | - | $1,269 | $12,690 | 1 | N/A | true | false |
| 15 | - | Fly Me to the Moon 3D | $6,777 | - | 1 | - | $6,777 | $23,230 | 3 | N/A | false | false |
| 16 | 10 | Bedtime Stories | $2,019 | -87.9% | 3 | -13 | $673 | $945,597 | 5 | N/A | false | false |
| 17 | 12 | The Abandoned | $1,621 | -69.2% | 10 | -2 | $162 | $54,088 | 3 | N/A | false | false |
| 18 | 9 | Saw V | $1,585 | -93.8% | 14 | - | $113 | $31,608 | 2 | N/A | false | false |
| 19 | 15 | Changeling | $1,239 | +445.8% | 2 | - | $619 | $17,800 | 4 | N/A | false | false |
