| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 3 | Gran Torino | $1,230,789 | -2% | 199 | +49 | $6,184 | $3,150,154 | 2 | Roadshow Films | false | false |
| 2 | 6 | Slumdog Millionaire | $880,744 | +5.6% | 122 | +50 | $7,219 | $5,301,869 | 7 | Icon Film Distribution | false | false |
| 3 | 2 | Bride Wars | $788,066 | -42.4% | 281 | -6 | $2,804 | $5,675,917 | 3 | 20th Century Fox International | false | false |
| 4 | 1 | Valkyrie | $779,470 | -43.2% | 232 | - | $3,359 | $2,627,475 | 2 | 20th Century Fox International | false | false |
| 5 | 4 | Underworld: Rise of the Lycans | $557,977 | -51% | 147 | - | $3,795 | $2,002,706 | 2 | Sony Pictures Releasing | false | false |
| 6 | 5 | Hotel for Dogs | $530,201 | -36.6% | 177 | -3 | $2,995 | $3,018,068 | 3 | Paramount Pictures International | false | false |
| 7 | 7 | Role Models | $492,317 | -33.5% | 178 | -1 | $2,765 | $3,148,184 | 3 | Universal Pictures International (UPI) | false | false |
| 8 | 9 | Revolutionary Road | $394,671 | -32.5% | 129 | -16 | $3,059 | $1,198,092 | 2 | Paramount Pictures International | false | false |
| 9 | 8 | Australia | $351,633 | -40.8% | 203 | -45 | $1,732 | $22,318,849 | 10 | 20th Century Fox International | false | false |
| 10 | 13 | The Curious Case of Benjamin Button | $329,124 | -33.5% | 194 | -17 | $1,696 | $9,688,997 | 6 | Warner Bros. | false | false |
| 11 | 10 | Bolt | $295,574 | -46.9% | 183 | -57 | $1,615 | $7,052,978 | 5 | Walt Disney Pictures | false | false |
| 12 | 16 | Twilight | $280,771 | -13.1% | 132 | -24 | $2,127 | $12,587,865 | 9 | Hoyts Distribution | false | false |
| 13 | 12 | Yes Man | $270,458 | -46.3% | 179 | -36 | $1,510 | $8,382,741 | 5 | Roadshow Films | false | false |
| 14 | 11 | Bedtime Stories | $257,148 | -49.1% | 167 | -48 | $1,539 | $9,968,453 | 6 | Walt Disney Pictures | false | false |
| 15 | 14 | Marley & Me | $254,051 | -41.2% | 166 | -42 | $1,530 | $5,797,815 | 5 | 20th Century Fox International | false | false |
| 16 | - | Milk | $236,834 | - | 50 | - | $4,736 | $334,600 | 1 | Universal Pictures International (UPI) | true | false |
| 17 | - | The Spirit | $215,826 | - | 141 | - | $1,530 | $217,059 | 1 | Hoyts Distribution | true | false |
| 18 | 18 | Doubt | $213,453 | -4.2% | 108 | +40 | $1,976 | $1,053,702 | 3 | Walt Disney Pictures | false | false |
| 19 | 17 | Madagascar: Escape 2 Africa | $176,650 | -33.6% | 141 | -59 | $1,252 | $13,833,013 | 8 | Paramount Pictures International | false | false |
| 20 | 15 | Seven Pounds | $146,103 | -61.3% | 156 | -78 | $936 | $3,515,249 | 4 | Sony Pictures Releasing | false | false |
| 21 | 19 | The Wrestler | $128,902 | -21.6% | 51 | +1 | $2,527 | $812,720 | 3 | Hopscotch Films | false | false |
| 22 | 22 | Vicky Cristina Barcelona | $75,701 | +8.6% | 62 | +9 | $1,220 | $1,679,331 | 6 | Hopscotch Films | false | false |
| 23 | 20 | The Tale of Despereaux | $60,444 | -60.4% | 93 | -81 | $649 | $1,483,851 | 4 | Universal Pictures International (UPI) | false | false |
| 24 | 21 | I've Loved You So Long | $58,160 | -16.8% | 28 | +2 | $2,077 | $1,062,511 | 6 | Palace Films | false | false |
| 25 | 23 | The Class | $48,051 | +5.7% | 11 | - | $4,368 | $128,544 | 2 | Sony Pictures Releasing | false | false |
| 26 | 35 | Burn After Reading | $28,323 | +868% | 6 | -7 | $4,720 | $6,566,638 | 16 | Universal Pictures International (UPI) | false | false |
| 27 | 25 | Frost/Nixon | $25,104 | -20.4% | 32 | -1 | $784 | $1,200,143 | 6 | Universal Pictures International (UPI) | false | false |
| 28 | - | Luck by Chance | $20,547 | - | 9 | - | $2,283 | $20,547 | 1 | - | true | false |
| 29 | 24 | Quantum of Solace | $18,652 | -50.7% | 25 | -15 | $746 | $20,145,097 | 11 | Sony Pictures Releasing | false | false |
| 30 | 27 | Wild Ocean | $15,980 | -42.9% | 2 | - | $7,990 | $947,383 | 33 | IMAX | false | false |
| 31 | - | The Day the Earth Stood Still | $11,612 | - | 24 | - | $483 | $5,211,958 | 6 | 20th Century Fox International | false | false |
| 32 | 28 | The Dark Knight | $8,436 | -40.6% | 5 | - | $1,687 | $39,846,199 | 29 | Warner Bros. | false | false |
| 33 | 29 | Grand Canyon Adventure: River at Risk | $6,780 | -44.9% | 1 | - | $6,780 | $319,383 | 33 | IMAX | false | false |
| 34 | 30 | Fly Me to the Moon 3D | $6,773 | -33.7% | 2 | - | $3,386 | $415,592 | 20 | IMAX | false | false |
| 35 | 39 | Bustin' Down the Door | $5,137 | +303.9% | 10 | +9 | $513 | $53,246 | 3 | Madman Entertainment | false | false |
| 36 | - | CC2C | $2,751 | - | 9 | - | $305 | $172,120 | 3 | Warner Bros. | false | false |
| 37 | - | Victory | $2,708 | - | 8 | - | $338 | $2,708 | 1 | Saini Enterprises | true | false |
| 38 | 32 | Four Christmases | $2,252 | -59.3% | 4 | -8 | $563 | $4,934,100 | 9 | Roadshow Films | false | false |
| 39 | 38 | African Adventure: Safari in the Okavango | $2,248 | +11.5% | 1 | - | $2,248 | $703,678 | 98 | IMAX | false | false |
| 40 | 37 | Haunted Castle | $2,139 | -11.8% | 2 | +1 | $1,069 | $3,701,030 | 385 | IMAX | false | false |
| 41 | 34 | Igor | $1,844 | -56.4% | 6 | -11 | $307 | $225,686 | 4 | Roadshow Films | false | false |
| 42 | - | Dolphins and Whales 3D: Tribes of the Ocean | $1,732 | - | 1 | - | $1,732 | $540,434 | 47 | IMAX | false | false |
| 43 | 33 | U2 3D | $1,661 | -65.7% | 1 | - | $1,661 | $972,885 | 43 | Roadshow Films | false | false |
| 44 | 31 | Santa vs. the Snowman 3D | $1,574 | -75.7% | 1 | - | $1,574 | $1,482,732 | 324 | IMAX | false | false |
| 45 | - | Dinosaurs: Giants of Patagonia | $1,530 | - | 2 | - | $765 | $2,052,300 | 87 | IMAX | false | false |
| 46 | 36 | Before the Rains | $1,116 | -58.3% | 2 | - | $558 | $29,898 | 4 | Rialto Distribution | false | false |
| 47 | - | In Bruges | $733 | - | 1 | - | $733 | $2,374,500 | 23 | Icon Film Distribution | false | false |
| 48 | - | City of Ember | $455 | - | 5 | - | $91 | $315,003 | 8 | Icon Film Distribution | false | false |
