| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | Paul Blart: Mall Cop | $21,500,000 | $21,623,182 | +$123,182 | +0.6% | 3,144 | $64,800,000 | $64,923,380 | 2 | Sony Pictures Releasing | - |
| 2 | 2 | - | Underworld: Rise of the Lycans | $20,700,000 | $20,828,511 | +$128,511 | +0.6% | 2,942 | $20,700,000 | $20,828,511 | 1 | Screen Gems | - |
| 3 | 3 | - | Gran Torino | $16,000,000 | $16,244,462 | +$244,462 | +1.5% | 3,045 | $97,576,000 | $97,819,975 | 7 | Warner Bros. | - |
| 4 | 4 | - | Hotel for Dogs | $12,360,000 | $12,860,944 | +$500,944 | +4.1% | 3,271 | $36,955,000 | $37,455,759 | 2 | DreamWorks | - |
| 5 | 5 | - | Slumdog Millionaire | $10,550,000 | $10,699,629 | +$149,629 | +1.4% | 1,411 | $55,916,000 | $56,065,245 | 11 | Fox Searchlight Pictures | - |
| 6 | 6 | - | My Bloody Valentine | $10,050,000 | $10,012,658 | -$37,342 | -0.4% | 2,534 | $37,725,000 | $37,687,394 | 2 | Lionsgate | - |
| 7 | 7 | - | Inkheart | $7,725,000 | $7,601,379 | -$123,621 | -1.6% | 2,655 | $7,725,000 | $7,601,379 | 1 | Warner Bros. | - |
| 8 | 8 | - | Bride Wars | $7,000,000 | $6,868,664 | -$131,336 | -1.9% | 2,621 | $48,702,000 | $48,570,928 | 3 | Twentieth Century Fox | - |
| 9 | 9 | - | The Curious Case of Benjamin Button | $6,000,000 | $6,085,919 | +$85,919 | +1.4% | 2,263 | $111,044,000 | $111,129,482 | 5 | Paramount Pictures | - |
| 10 | 10 | - | Notorious | $5,700,000 | $5,779,692 | +$79,692 | +1.4% | 1,641 | $31,795,000 | $31,874,538 | 2 | Fox Searchlight Pictures | - |
| 11 | 11 | - | Defiance | $5,432,000 | $5,666,785 | +$234,785 | +4.3% | 1,793 | $18,329,000 | $18,564,544 | 4 | Paramount Vantage | - |
| 12 | 12 | - | Revolutionary Road | $5,268,000 | $5,185,146 | -$82,854 | -1.6% | 1,058 | $11,867,000 | $11,784,049 | 5 | Paramount Vantage | - |
| 13 | 13 | - | The Unborn | $4,530,000 | $4,359,865 | -$170,135 | -3.8% | 2,107 | $39,400,000 | $39,230,025 | 3 | Universal Pictures | - |
| 14 | 14 | - | The Wrestler | $3,700,000 | $3,745,643 | +$45,643 | +1.2% | 566 | $9,512,000 | $9,557,610 | 6 | Fox Searchlight Pictures | - |
| 15 | 16 | +1 | Frost/Nixon | $3,022,000 | $3,022,250 | +$250 | <0.1% | 1,099 | $12,006,000 | $12,005,811 | 8 | Universal Pictures | - |
| 16 | 15 | -1 | Marley & Me | $3,000,000 | $3,031,969 | +$31,969 | +1.1% | 2,036 | $138,060,000 | $138,092,165 | 5 | Twentieth Century Fox | - |
| 17 | 17 | - | Last Chance Harvey | $3,000,000 | $2,865,298 | -$134,702 | -4.5% | 1,108 | $9,665,000 | $9,529,976 | 5 | Overture Films | - |
| 18 | 18 | - | Bedtime Stories | $1,839,000 | $1,955,408 | +$116,408 | +6.3% | 1,660 | $107,485,000 | $107,600,474 | 5 | Walt Disney Studios Motion Pictures | - |
| 19 | 19 | - | Valkyrie | $1,537,000 | $1,509,786 | -$27,214 | -1.8% | 1,110 | $80,768,000 | $80,740,385 | 5 | United Artists | - |
| 20 | 20 | - | The Reader | $1,416,000 | $1,403,410 | -$12,590 | -0.9% | 367 | $9,674,000 | $9,661,121 | 7 | The Weinstein Company | - |
| 21 | 22 | +1 | Not Easily Broken | $950,000 | $960,618 | +$10,618 | +1.1% | 483 | $9,740,000 | $9,750,971 | 3 | Screen Gems | - |
| 22 | 21 | -1 | Twilight | $937,000 | $978,618 | +$41,618 | +4.4% | 552 | $185,986,000 | $186,027,660 | 10 | Summit Entertainment | - |
| 23 | 25 | +2 | Yes Man | $875,000 | $803,019 | -$71,981 | -8.2% | 704 | $95,455,000 | $95,383,486 | 6 | Warner Bros. | - |
| 24 | 23 | -1 | Milk | $864,000 | $884,715 | +$20,715 | +2.4% | 250 | $21,632,000 | $21,637,349 | 9 | Focus Features | - |
| 25 | 24 | -1 | Doubt | $852,000 | $847,855 | -$4,145 | -0.5% | 404 | $26,757,000 | $26,753,136 | 7 | Miramax | - |
| 26 | 27 | +1 | Madagascar: Escape 2 Africa | $513,000 | $509,443 | -$3,557 | -0.7% | 303 | $178,857,000 | $178,853,694 | 12 | DreamWorks | - |
| 27 | 28 | +1 | Rachel Getting Married | $465,000 | $459,641 | -$5,359 | -1.2% | 370 | $11,258,000 | $11,252,249 | 17 | Sony Pictures Classics | - |
| 28 | 30 | +2 | The Tale of Despereaux | $283,000 | $288,540 | +$5,540 | +2% | 380 | $49,599,000 | $49,604,065 | 6 | Universal Pictures | - |
| 29 | 35 | +6 | Waltz with Bashir | $153,000 | $150,458 | -$2,542 | -1.7% | 25 | $738,000 | $754,796 | 5 | Sony Pictures Classics | - |
| 30 | 37 | +7 | Che: Part One/Che: Part Two | $121,000 | $130,607 | +$9,607 | +7.9% | 26 | $809,000 | $706,641 | 7 | IFC Films | - |
| 31 | 41 | +10 | Role Models | $75,000 | $75,705 | +$705 | +0.9% | 147 | $67,266,000 | $67,266,300 | 12 | Universal Pictures | - |
| 32 | 40 | +8 | Vicky Cristina Barcelona | $73,500 | $77,453 | +$3,953 | +5.4% | 53 | $23,114,000 | $23,118,152 | 24 | Metro-Goldwyn-Mayer (MGM) | - |
| 33 | 42 | +9 | Outlander | $53,200 | $59,581 | +$6,381 | +12% | 81 | $53,200 | $59,581 | 1 | Third Rail Releasing | - |
| 34 | 49 | +15 | Wendy and Lucy | $36,600 | $32,672 | -$3,928 | -10.7% | 8 | $198,000 | $193,690 | 7 | Oscilloscope | - |
| 35 | 56 | +21 | Killshot | $10,060 | $10,741 | +$681 | +6.8% | 5 | $10,060 | $10,741 | 1 | The Weinstein Company | - |
| 36 | 59 | +23 | Soul Men | $10,000 | $9,329 | -$671 | -6.7% | 38 | $12,076,000 | $12,075,660 | 12 | Metro-Goldwyn-Mayer (MGM) | - |
| 37 | 60 | +23 | Owl and the Sparrow | $8,870 | $8,941 | +$71 | +0.8% | 4 | $19,880 | $21,889 | 2 | Wave Releasing | - |
