| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Underworld: Rise of the Lycans | $53,735 | - | 9 | - | $5,970 | $53,735 | 1 | Alexandra Films | true | false |
| 2 | 1 | Yes Man | $32,903 | -47.9% | 9 | - | $3,655 | $117,935 | 2 | Alexandra Films | false | false |
| 3 | 3 | Open Season | $29,200 | +25.7% | 1 | - | $29,200 | $194,206 | 116 | Alexandra Films | false | false |
| 4 | - | The Tale of Despereaux | $21,605 | - | 12 | - | $1,800 | $21,605 | 1 | United International Pictures | true | false |
| 5 | - | Arn: The Knight Templar | $20,609 | - | 5 | - | $4,121 | $20,609 | 1 | - | true | false |
| 6 | 2 | Twilight | $18,933 | -32% | 8 | - | $2,366 | $57,164 | 2 | - | false | false |
| 7 | 5 | Bolt | $15,038 | -15.2% | 11 | - | $1,367 | $260,667 | 6 | Sunny Films | false | false |
| 8 | 6 | Changeling | $11,856 | -19.7% | 6 | - | $1,976 | $69,577 | 3 | Prooptiki | false | false |
| 9 | 4 | Transporter 3 | $11,742 | -42.4% | 9 | - | $1,304 | $97,262 | 3 | Alexandra Films | false | false |
| 10 | 7 | Australia | $7,228 | -24.7% | 13 | -3 | $556 | $159,105 | 5 | Alexandra Films | false | false |
| 11 | 9 | Bedtime Stories | $2,971 | -59.5% | 9 | -1 | $330 | $72,060 | 4 | Sunny Films | false | false |
| 12 | 12 | Vicky Cristina Barcelona | $2,556 | +3.5% | 5 | - | $511 | $75,106 | 7 | Sunny Films | false | false |
| 13 | 8 | Role Models | $2,401 | -69.4% | 5 | -1 | $480 | $58,746 | 4 | Prooptiki | false | false |
| 14 | 11 | Madagascar: Escape 2 Africa | $1,909 | -63.8% | 6 | -8 | $318 | $268,503 | 9 | Prooptiki | false | false |
| 15 | 10 | Pride and Glory | $1,830 | -70.2% | 8 | - | $228 | $59,634 | 4 | Alexandra Films | false | false |
| 16 | 14 | Journey to the Center of the Earth | $1,364 | -32.7% | 5 | - | $272 | $371,983 | 14 | Alexandra Films | false | false |
| 17 | 15 | Burn After Reading | $720 | -17.5% | 1 | - | $720 | $39,738 | 8 | Cinema City | false | false |
| 18 | 17 | The World is Big and Salvation Lurks Around the Corner | $323 | -36% | 3 | -1 | $107 | $76,624 | 16 | Alexandra Films | false | false |
| 19 | 24 | Zift | $270 | +109.3% | 3 | - | $90 | $182,878 | 18 | Alexandra Films | false | false |
| 20 | 19 | High School Musical 3: Senior Year | $210 | -48.9% | 4 | -2 | $52 | $51,572 | 10 | Sunny Films | false | false |
| 21 | 16 | Four Christmases | $193 | -73% | 5 | -2 | $38 | $140,212 | 6 | Alexandra Films | false | false |
| 22 | 23 | Nights in Rodanthe | $150 | +15.4% | 3 | - | $50 | $54,687 | 11 | Alexandra Films | false | false |
| 23 | 18 | Nim's Island | $149 | -69.7% | 4 | +1 | $37 | $13,398 | 6 | - | false | false |
| 24 | 13 | The Day the Earth Stood Still | $142 | -94.2% | 1 | -7 | $142 | $283,714 | 7 | Alexandra Films | false | false |
| 25 | - | City of Ember | $112 | - | 1 | - | $112 | $82,653 | 11 | - | false | false |
| 26 | 29 | Maradona, the Hand of God | $100 | +170.3% | 3 | - | $33 | $8,245 | 6 | Alexandra Films | false | false |
| 27 | 20 | Body of Lies | $73 | -80.8% | 3 | - | $24 | $217,282 | 9 | Alexandra Films | false | false |
| 28 | - | 99 Francs | $64 | - | 1 | - | $64 | $12,351 | 38 | Big Bang Media | false | false |
| 29 | 26 | Mamma Mia! | $25 | -71.6% | 2 | -1 | $12 | $297,089 | 21 | Prooptiki | false | false |
| 30 | - | Molière | $20 | - | 1 | - | $20 | $1,276 | 17 | Big Bang Media | false | false |
| 31 | - | Righteous Kill | $19 | - | 1 | - | $19 | $152,760 | 14 | Sunny Films | false | false |
| 32 | - | Love in the Time of Cholera | $13 | - | 1 | - | $13 | $37,160 | 35 | Prooptiki | false | false |
| 33 | - | My Blueberry Nights | $12 | - | 2 | - | $6 | $33,261 | 33 | Sunny Films | false | false |
| 34 | - | Wild Child | $12 | - | 1 | - | $12 | $57,416 | 16 | Prooptiki | false | false |
| 35 | 32 | WALL·E | $3 | -57.1% | 1 | - | $3 | $145,634 | 21 | Sunny Films | false | false |
