| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Yes Man | $250,059 | - | 60 | - | $4,167 | $250,059 | 1 | NuMetro Distribution | true | false |
| 2 | 2 | Mr. Bones 2: Back from the Past | $155,019 | -29.3% | 93 | - | $1,666 | $3,148,431 | 6 | United International Pictures | false | false |
| 3 | 1 | Bolt | $109,411 | -61.7% | 74 | - | $1,478 | $571,909 | 2 | Ster-Kinekor Pictures | false | false |
| 4 | 3 | Madagascar: Escape 2 Africa | $108,458 | -25.6% | 94 | - | $1,153 | $1,879,113 | 5 | United International Pictures | false | false |
| 5 | - | The Tale of Despereaux | $97,594 | - | 49 | - | $1,991 | $97,594 | 1 | United International Pictures | true | false |
| 6 | - | Pride and Glory | $85,716 | - | 40 | - | $2,142 | $85,716 | 1 | NuMetro Distribution | true | false |
| 7 | 4 | Australia | $74,343 | -44.1% | 63 | - | $1,180 | $306,009 | 2 | NuMetro Distribution | false | false |
| 8 | 5 | Twilight | $72,261 | -19.3% | 46 | +1 | $1,570 | $454,962 | 3 | NuMetro Distribution | false | false |
| 9 | 7 | Quantum of Solace | $42,620 | -44.6% | 48 | -18 | $887 | $2,048,650 | 7 | Ster-Kinekor Pictures | false | false |
| 10 | - | Vicky Cristina Barcelona | $36,923 | - | 17 | - | $2,171 | $36,923 | 1 | United International Pictures | true | false |
| 11 | 8 | Vaatjie Sien sy Gat | $33,515 | -49.4% | 32 | -2 | $1,047 | $143,531 | 2 | Ster-Kinekor Pictures | false | false |
| 12 | 6 | The Day the Earth Stood Still | $33,341 | -59.8% | 42 | -27 | $793 | $630,408 | 4 | NuMetro Distribution | false | false |
| 13 | 9 | Make It Happen | $22,491 | -55.5% | 39 | -15 | $576 | $241,221 | 3 | United International Pictures | false | false |
| 14 | 10 | The Women | $12,598 | -43.7% | 16 | -6 | $787 | $361,745 | 5 | Ster-Kinekor Pictures | false | false |
| 15 | 11 | Rab Ne Bana Di Jodi | $10,899 | -39.4% | 7 | -1 | $1,557 | $141,751 | 4 | NuMetro Distribution | false | false |
| 16 | 12 | Wild Child | $8,319 | -30.1% | 18 | -6 | $462 | $476,384 | 8 | United International Pictures | false | false |
| 17 | 15 | Elegy | $6,801 | -37.1% | 6 | - | $1,133 | $30,131 | 2 | NuMetro Distribution | false | false |
| 18 | 16 | Body of Lies | $4,010 | -55.6% | 9 | -2 | $445 | $520,155 | 9 | NuMetro Distribution | false | false |
| 19 | 14 | How to Lose Friends & Alienate People | $3,324 | -70.4% | 3 | -7 | $1,108 | $38,302 | 3 | United International Pictures | false | false |
| 20 | 19 | Boy A | $2,842 | -22.3% | 3 | - | $947 | $10,340 | 2 | Ster-Kinekor Pictures | false | false |
| 21 | - | The Boy in the Striped Pajamas | $2,723 | - | 4 | - | $680 | $27,410 | 5 | Ster-Kinekor Pictures | false | false |
| 22 | 20 | The Counterfeiters | $2,706 | -21% | 4 | - | $676 | $71,158 | 9 | Ster-Kinekor Pictures | false | false |
| 23 | - | The Band's Visit | $2,086 | - | 3 | - | $695 | $56,501 | 10 | Ster-Kinekor Pictures | false | false |
| 24 | 13 | Nick and Norah's Infinite Playlist | $2,055 | -82.7% | 6 | -9 | $342 | $40,223 | 3 | Ster-Kinekor Pictures | false | false |
| 25 | 22 | Fugitive Pieces | $1,089 | -13.6% | 2 | - | $544 | $22,848 | 10 | United International Pictures | false | false |
