| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Twilight | $354,523 | - | 41 | - | $8,646 | $354,523 | 1 | N/A | true | false |
| 2 | 1 | Bolt | $237,232 | -38.3% | 41 | - | $5,786 | $734,730 | 2 | N/A | false | false |
| 3 | - | The Tale of Despereaux | $122,336 | - | 30 | - | $4,077 | $122,336 | 1 | N/A | true | false |
| 4 | 4 | Australia | $85,320 | -34.8% | 36 | - | $2,370 | $252,880 | 2 | N/A | false | false |
| 5 | 2 | The Day the Earth Stood Still | $66,037 | -50.1% | 46 | - | $1,435 | $865,282 | 4 | N/A | false | false |
| 6 | - | The Forbidden Kingdom | $63,793 | - | 26 | - | $2,453 | $63,793 | 1 | N/A | true | false |
| 7 | 3 | Madagascar: Escape 2 Africa | $54,539 | -58.4% | 50 | - | $1,090 | $1,776,906 | 5 | N/A | false | false |
| 8 | 5 | The Strangers | $43,465 | -48.8% | 23 | - | $1,889 | $156,016 | 2 | N/A | false | false |
| 9 | 6 | Four Christmases | $29,712 | -56.8% | 24 | - | $1,238 | $215,750 | 3 | N/A | false | false |
| 10 | 9 | Quantum of Solace | $19,919 | +293.8% | 8 | +6 | $2,489 | $518,861 | 7 | N/A | false | false |
| 11 | 8 | Burn After Reading | $9,261 | -58.9% | 15 | - | $617 | $70,198 | 3 | N/A | false | false |
| 12 | 7 | The Host | $4,491 | -89.8% | 23 | - | $195 | $61,149 | 2 | N/A | false | false |
| 13 | 10 | The Return | $365 | -89.2% | 10 | - | $36 | $50,389 | 4 | N/A | false | false |
