| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Day the Earth Stood Still | $677,421 | - | 92 | - | $7,363 | $677,421 | 1 | 20th Century Fox International | true | false |
| 2 | - | Twilight | $483,329 | - | 79 | - | $6,118 | $483,329 | 1 | Alfa Films | true | false |
| 3 | 1 | Madagascar: Escape 2 Africa | $292,517 | -25.6% | 116 | +15 | $2,521 | $4,483,672 | 5 | Paramount Pictures International | false | false |
| 4 | - | El ratón Pérez 2 | $222,454 | - | 92 | - | $2,417 | $222,454 | 1 | Walt Disney Pictures | true | false |
| 5 | 2 | Four Christmases | $56,378 | -44.1% | 37 | -3 | $1,523 | $321,919 | 3 | Distribution Company | false | false |
| 6 | 3 | Body of Lies | $55,287 | -40.1% | 49 | +4 | $1,128 | $841,691 | 6 | Warner Bros. | false | false |
| 7 | 4 | High School Musical 3: Senior Year | $24,556 | -62.4% | 48 | -65 | $511 | $1,276,845 | 6 | Walt Disney Pictures | false | false |
| 8 | 6 | The Duchess | $21,699 | -41.5% | 15 | +1 | $1,446 | $190,603 | 4 | United International Pictures | false | false |
| 9 | - | Ben X | $17,983 | - | 20 | - | $899 | $17,983 | 1 | Distribution Company | true | false |
| 10 | 5 | Quarantine | $17,049 | -71% | 27 | -3 | $631 | $339,611 | 5 | Sony Pictures Releasing | false | false |
| 11 | 7 | Righteous Kill | $14,647 | -54.3% | 19 | -21 | $770 | $547,170 | 7 | CDI Films | false | false |
| 12 | 9 | Quantum of Solace | $12,071 | -57.4% | 8 | -8 | $1,508 | $1,273,742 | 9 | Sony Pictures Releasing | false | false |
| 13 | 10 | Che: Part One | $10,664 | -50.2% | 10 | -18 | $1,066 | $644,508 | 8 | Alfa Films | false | false |
| 14 | - | The Pope's Toilet | $10,635 | - | 7 | - | $1,519 | $10,635 | 1 | Primer Plano Film Group | true | false |
| 15 | 8 | Death Sentence | $9,500 | -66.5% | 21 | -12 | $452 | $177,449 | 5 | Distribution Company | false | false |
| 16 | 22 | The Bank Job | $4,575 | -37.3% | 12 | -13 | $381 | $620,339 | 12 | Alfa Films | false | false |
| 17 | 21 | My Mom's New Boyfriend | $4,227 | -54.4% | 4 | -12 | $1,056 | $144,755 | 8 | - | false | false |
| 18 | 24 | Tear This Heart Out | $3,825 | -31.8% | 6 | -1 | $637 | $47,069 | 6 | 20th Century Fox International | false | false |
| 19 | 14 | RocknRolla | $3,721 | -76.3% | 10 | -5 | $372 | $73,857 | 4 | Warner Bros. | false | false |
| 20 | 12 | Bella | $3,377 | -81.5% | 3 | -5 | $1,125 | $25,249 | 2 | CDI Films | false | false |
| 21 | 11 | Fly Me to the Moon 3D | $2,940 | -85.4% | 35 | -10 | $84 | $73,643 | 3 | Distribution Company | false | false |
| 22 | 23 | Elegy | $2,650 | -62.5% | 7 | -13 | $378 | $170,761 | 7 | Distribution Company | false | false |
| 23 | 16 | Flawless | $2,134 | -81.8% | 8 | -13 | $266 | $251,236 | 9 | Distribution Company | false | false |
| 24 | 17 | Death Defying Acts | $1,968 | -80.3% | 7 | -15 | $281 | $119,439 | 6 | Alfa Films | false | false |
| 25 | 25 | Beverly Hills Chihuahua | $1,770 | -61.2% | 6 | -24 | $295 | $1,530,243 | 13 | Walt Disney Pictures | false | false |
| 26 | 27 | Red Like the Sky 2008 Re-release | $1,656 | -49.7% | 3 | - | $552 | $23,154 | 5 | Primer Plano Film Group | false | false |
| 27 | 19 | Ira & Abby | $1,413 | -84.8% | 1 | -12 | $1,413 | $43,129 | 4 | CDI Films | false | false |
| 28 | 13 | Planet Terror | $1,086 | -93.3% | 8 | -16 | $135 | $81,108 | 4 | Pachamama Cine | false | false |
| 29 | 20 | Saw V | $969 | -89.5% | 6 | -19 | $161 | $1,030,324 | 10 | Walt Disney Pictures | false | false |
| 30 | 30 | Fados | $727 | -53.1% | 1 | -5 | $727 | $32,701 | 6 | Distribution Company | false | false |
| 31 | 32 | Black Christmas | $712 | -37.9% | 5 | -4 | $142 | $95,948 | 8 | Distribution Company | false | false |
| 32 | 18 | The Boy in the Striped Pajamas | $604 | -93.8% | 2 | -11 | $302 | $75,556 | 5 | Walt Disney Pictures | false | false |
| 33 | 15 | Deception | $594 | -95.4% | 1 | -11 | $594 | $60,613 | 4 | Alfa Films | false | false |
| 34 | 36 | Manual of Love 2008 Re-release | $571 | +115.5% | 2 | -2 | $285 | $133,883 | 15 | Notro Films | false | false |
| 35 | 26 | Max Payne | $450 | -89% | 2 | -23 | $225 | $165,181 | 7 | 20th Century Fox International | false | false |
| 36 | 29 | Burn After Reading | $440 | -76.2% | 1 | -8 | $440 | $849,266 | 11 | United International Pictures | false | false |
| 37 | 39 | Four Minutes | $405 | +153.1% | 1 | - | $405 | $158,741 | 19 | Alfa Films | false | false |
| 38 | 41 | My Brother is an Only Child | $278 | +371.2% | 1 | - | $278 | $222,210 | 16 | Alfa Films | false | false |
| 39 | 43 | Shara | $261 | +866.7% | 1 | - | $261 | $43,502 | 10 | Zeta Films | false | false |
| 40 | 28 | La leyenda | $259 | -87.1% | 2 | -13 | $129 | $215,086 | 7 | United International Pictures | false | false |
| 41 | 37 | Mamma Mia! | $191 | -10.7% | 1 | -1 | $191 | $1,433,548 | 20 | United International Pictures | false | false |
| 42 | 42 | Days of Darkness | $191 | +260.4% | 1 | - | $191 | $15,233 | 12 | Alfa Films | false | false |
| 43 | 33 | The Magic Flute | $127 | -83.7% | 1 | -4 | $127 | $26,492 | 11 | Distribution Company | false | false |
