| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | The Day the Earth Stood Still | $31,000,000 | $30,480,153 | -$519,847 | -1.7% | 3,560 | $31,000,000 | $30,480,153 | 1 | Twentieth Century Fox | - |
| 2 | 2 | - | Four Christmases | $13,270,000 | $13,074,470 | -$195,530 | -1.5% | 3,540 | $87,972,000 | $87,775,974 | 3 | Warner Bros. | - |
| 3 | 3 | - | Twilight | $8,013,000 | $7,951,131 | -$61,869 | -0.8% | 3,649 | $150,108,000 | $150,045,826 | 4 | Summit Entertainment | - |
| 4 | 4 | - | Bolt | $7,506,000 | $7,464,282 | -$41,718 | -0.6% | 3,133 | $88,891,000 | $88,849,005 | 4 | Walt Disney Studios Motion Pictures | - |
| 5 | 5 | - | Australia | $4,285,000 | $4,169,277 | -$115,723 | -2.7% | 2,703 | $37,883,000 | $37,767,253 | 3 | Twentieth Century Fox | - |
| 6 | 6 | - | Quantum of Solace | $3,800,000 | $3,715,522 | -$84,478 | -2.2% | 2,635 | $157,668,000 | $157,583,232 | 5 | Sony Pictures Releasing | - |
| 7 | 7 | - | Nothing Like the Holidays | $3,500,000 | $3,531,664 | +$31,664 | +0.9% | 1,671 | $3,500,000 | $3,531,664 | 1 | Overture Films | - |
| 8 | 8 | - | Madagascar: Escape 2 Africa | $3,250,000 | $3,181,231 | -$68,769 | -2.1% | 2,768 | $170,006,000 | $169,937,394 | 6 | DreamWorks | - |
| 9 | 9 | - | Milk | $2,636,000 | $2,598,638 | -$37,362 | -1.4% | 328 | $7,630,000 | $7,590,976 | 3 | Focus Features | - |
| 10 | 10 | - | Transporter 3 | $2,250,000 | $2,351,229 | +$101,229 | +4.5% | 2,541 | $29,276,000 | $29,377,088 | 3 | Lionsgate | - |
| 11 | 11 | - | Slumdog Millionaire | $2,200,000 | $2,175,518 | -$24,482 | -1.1% | 169 | $8,073,000 | $8,048,764 | 5 | Fox Searchlight Pictures | - |
| 12 | 12 | - | Cadillac Records | $1,600,000 | $1,585,407 | -$14,593 | -0.9% | 688 | $5,924,000 | $5,909,492 | 2 | Sony Pictures Releasing | - |
| 13 | 13 | - | Role Models | $1,527,000 | $1,543,625 | +$16,625 | +1.1% | 1,328 | $64,117,000 | $64,133,465 | 6 | Universal Pictures | - |
| 14 | 14 | - | Punisher: War Zone | $1,380,000 | $1,383,898 | +$3,898 | +0.3% | 2,508 | $7,008,000 | $7,011,427 | 2 | Lionsgate | - |
| 15 | 15 | - | Rab Ne Bana Di Jodi | $1,250,000 | $920,995 | -$329,005 | -26.3% | 83 | $1,250,000 | $920,995 | 1 | Yash Raj Films | - |
| 16 | 18 | +2 | Delgo | $916,000 | $511,920 | -$404,080 | -44.1% | 2,160 | $916,000 | $511,920 | 1 | Freestyle Releasing | - |
| 17 | 16 | -1 | The Boy in the Striped Pajamas | $702,000 | $685,465 | -$16,535 | -2.4% | 679 | $7,780,000 | $7,763,062 | 6 | Miramax | - |
| 18 | 17 | -1 | Frost/Nixon | $630,000 | $626,377 | -$3,623 | -0.6% | 39 | $878,000 | $873,836 | 2 | Universal Pictures | - |
| 19 | 19 | - | Doubt | $525,000 | $507,226 | -$17,774 | -3.4% | 15 | $525,000 | $507,226 | 1 | Miramax | - |
| 20 | 20 | - | Gran Torino | $284,000 | $271,720 | -$12,280 | -4.3% | 6 | $284,000 | $271,720 | 1 | Warner Bros. | - |
| 21 | 21 | - | Changeling | $248,000 | $256,840 | +$8,840 | +3.6% | 393 | $35,153,000 | $35,161,607 | 8 | Universal Pictures | - |
| 22 | 22 | - | Rachel Getting Married | $246,000 | $221,323 | -$24,677 | -10% | 151 | $9,586,000 | $9,560,874 | 11 | Sony Pictures Classics | - |
| 23 | 24 | +1 | Eagle Eye | $190,000 | $198,135 | +$8,135 | +4.3% | 320 | $100,632,000 | $100,639,704 | 12 | DreamWorks | - |
| 24 | 25 | +1 | The Reader | $170,000 | $168,051 | -$1,949 | -1.1% | 8 | $182,000 | $179,970 | 1 | The Weinstein Company | - |
| 25 | 30 | +5 | I've Loved You So Long | $115,000 | $102,590 | -$12,410 | -10.8% | 46 | $1,930,000 | $1,917,952 | 8 | Sony Pictures Classics | - |
| 26 | 29 | +3 | Synecdoche, New York | $114,000 | $104,777 | -$9,223 | -8.1% | 97 | $2,440,000 | $2,430,402 | 8 | Sony Pictures Classics | - |
| 27 | 28 | +1 | The Dark Knight | $111,000 | $112,253 | +$1,253 | +1.1% | 205 | $530,722,000 | $530,723,626 | 22 | Warner Bros. | - |
| 28 | 32 | +4 | Zack and Miri Make a Porno | $95,000 | $100,786 | +$5,786 | +6.1% | 163 | $31,042,000 | $31,047,926 | 7 | The Weinstein Company | - |
| 29 | 33 | +4 | Happy-Go-Lucky | $87,000 | $86,872 | -$128 | -0.1% | 144 | $3,015,000 | $3,014,482 | 10 | Miramax | - |
| 30 | 37 | +7 | Che: Part One/Che: Part Two | $60,100 | $61,070 | +$970 | +1.6% | 2 | $60,100 | $61,070 | 1 | IFC Films | - |
| 31 | 38 | +7 | Soul Men | $50,000 | $49,944 | -$56 | -0.1% | 95 | $11,967,000 | $11,966,888 | 6 | Metro-Goldwyn-Mayer (MGM) | - |
| 32 | 40 | +8 | Igor | $47,000 | $45,700 | -$1,300 | -2.8% | 118 | $19,391,000 | $19,389,266 | 13 | Metro-Goldwyn-Mayer (MGM) | - |
| 33 | 42 | +9 | Vicky Cristina Barcelona | $40,000 | $40,479 | +$479 | +1.2% | 28 | $22,565,000 | $22,565,132 | 18 | Metro-Goldwyn-Mayer (MGM) | - |
| 34 | 54 | +20 | Wendy and Lucy | $21,400 | $18,218 | -$3,182 | -14.9% | 2 | $28,600 | $25,443 | 1 | Oscilloscope | - |
| 35 | 49 | +14 | Religulous | $19,100 | $21,664 | +$2,564 | +13.4% | 42 | $12,993,000 | $12,995,673 | 11 | Lionsgate | - |
