| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Madagascar: Escape 2 Africa | $1,653,150 | - | 156 | - | $10,597 | $1,653,150 | 1 | Paramount Pictures International | true | false |
| 2 | 1 | High School Musical 3: Senior Year | $219,970 | -53.6% | 88 | +2 | $2,499 | $691,246 | 2 | Walt Disney Pictures | false | false |
| 3 | 2 | Body of Lies | $152,410 | -31.3% | 46 | +4 | $3,313 | $445,663 | 2 | Warner Bros. | false | false |
| 4 | - | Quarantine | $99,606 | - | 30 | - | $3,320 | $99,606 | 1 | Sony Pictures Releasing | true | false |
| 5 | 3 | Righteous Kill | $68,835 | -42.3% | 40 | -4 | $1,720 | $401,845 | 3 | CDI Films | false | false |
| 6 | - | Death Sentence | $60,679 | - | 31 | - | $1,957 | $60,679 | 1 | Distribution Company | true | false |
| 7 | 4 | Quantum of Solace | $50,986 | -51.2% | 43 | -44 | $1,185 | $1,045,752 | 5 | Sony Pictures Releasing | false | false |
| 8 | 5 | Che: Part One | $48,056 | -42.8% | 44 | -12 | $1,092 | $539,189 | 4 | Alfa Films | false | false |
| 9 | - | The Boy in the Striped Pajamas | $32,381 | - | 13 | - | $2,490 | $32,381 | 1 | Walt Disney Pictures | true | false |
| 10 | 6 | Saw V | $29,281 | -52% | 39 | -21 | $750 | $974,367 | 6 | Walt Disney Pictures | false | false |
| 11 | 10 | Elegy | $20,687 | -35.2% | 22 | - | $940 | $127,389 | 3 | Distribution Company | false | false |
| 12 | 11 | Max Payne | $18,857 | -39.7% | 21 | -7 | $897 | $132,954 | 3 | 20th Century Fox International | false | false |
| 13 | 14 | Flawless | $17,172 | -7.4% | 22 | - | $780 | $208,393 | 5 | Distribution Company | false | false |
| 14 | 12 | The Bank Job | $15,798 | -47.1% | 26 | -7 | $607 | $580,959 | 8 | Alfa Films | false | false |
| 15 | 19 | Late Bloomers | $13,843 | +21.1% | 4 | - | $3,460 | $28,773 | 2 | Primer Plano Film Group | false | false |
| 16 | 9 | Beverly Hills Chihuahua | $12,831 | -66.2% | 54 | -7 | $237 | $1,486,919 | 9 | Walt Disney Pictures | false | false |
| 17 | 13 | Burn After Reading | $10,785 | -61.4% | 17 | -26 | $634 | $837,356 | 7 | United International Pictures | false | false |
| 18 | 8 | Death Defying Acts | $8,893 | -83.4% | 13 | -16 | $684 | $80,332 | 2 | Alfa Films | false | false |
| 19 | - | Red Like the Sky 2008 Re-release | $7,292 | - | 4 | - | $1,823 | $7,292 | 1 | Primer Plano Film Group | true | false |
| 20 | 21 | Black Christmas | $7,073 | -28.5% | 17 | -5 | $416 | $85,748 | 4 | Distribution Company | false | false |
| 21 | 22 | Fados | $6,364 | -29.6% | 4 | - | $1,591 | $19,528 | 2 | Distribution Company | false | false |
| 22 | 18 | Journey to the Center of the Earth | $4,119 | -65.3% | 1 | -1 | $4,119 | $891,507 | 21 | Distribution Company | false | false |
| 23 | 17 | Tear This Heart Out | $3,946 | -72.3% | 7 | - | $563 | $23,681 | 2 | 20th Century Fox International | false | false |
| 24 | 16 | My Mom's New Boyfriend | $3,346 | -78% | 5 | -10 | $669 | $101,600 | 4 | - | false | false |
| 25 | 28 | Manual of Love 2008 Re-release | $2,707 | -11.9% | 5 | +1 | $541 | $127,349 | 11 | Notro Films | false | false |
| 26 | 26 | Two Friends and a Burglar | $2,304 | -36.6% | 4 | - | $576 | $7,957 | 2 | Primer Plano Film Group | false | false |
| 27 | 25 | Aniceto | $1,937 | -61.7% | 3 | -4 | $645 | $120,251 | 26 | Primer Plano Film Group | false | false |
| 28 | 15 | The Nightmare Before Christmas 2009 3D Release | $1,367 | -91.6% | 1 | -2 | $1,367 | $203,037 | 6 | Walt Disney Pictures | false | false |
| 29 | 31 | Shara | $776 | -27.4% | 2 | +1 | $388 | $41,410 | 6 | Zeta Films | false | false |
| 30 | 30 | Disco | $607 | -57.8% | 1 | -3 | $607 | $21,122 | 5 | Pachamama Cine | false | false |
| 31 | 29 | The Women | $570 | -66.1% | 2 | -3 | $285 | $126,798 | 6 | CDI Films | false | false |
| 32 | 33 | The Paranoids | $435 | -36.1% | 1 | - | $435 | $39,419 | 7 | Primer Plano Film Group | false | false |
| 33 | 39 | Four Minutes | $387 | +34.4% | 1 | - | $387 | $156,561 | 15 | Alfa Films | false | false |
| 34 | 42 | You Don't Mess with the Zohan | $321 | +141.4% | 3 | +2 | $107 | $650,950 | 12 | Sony Pictures Releasing | false | false |
| 35 | 38 | My Brother is an Only Child | $268 | -27.8% | 1 | -1 | $268 | $220,637 | 12 | Alfa Films | false | false |
| 36 | 36 | The Camera Obscura 2008 Re-release | $253 | -36.1% | 1 | - | $253 | $63,360 | 8 | Distribution Company | false | false |
| 37 | 49 | Reasons for Not Falling in Love | $173 | +424.2% | 2 | - | $86 | $528,981 | 14 | Distribution Company | false | false |
| 38 | 45 | The Magic Flute | $150 | +41.5% | 1 | - | $150 | $23,703 | 7 | Distribution Company | false | false |
| 39 | 41 | Mamma Mia! | $133 | -10.1% | 1 | - | $133 | $1,443,725 | 16 | United International Pictures | false | false |
| 40 | - | Café de los maestros | $115 | - | 1 | - | $115 | $94,661 | 24 | Alfa Films | false | false |
| 41 | 44 | Days of Darkness | $104 | -16.1% | 1 | - | $104 | $14,470 | 8 | Alfa Films | false | false |
| 42 | 50 | La próxima estación | $80 | +196.3% | 1 | - | $80 | $122,213 | 14 | Primer Plano Film Group | false | false |
| 43 | 34 | Don't Look Down | $50 | -91.6% | 1 | - | $50 | $16,991 | 6 | Primer Plano Film Group | false | false |
| 44 | 47 | A Boyfriend for My Wife | $45 | -46.4% | 1 | -3 | $45 | $5,655,199 | 17 | Walt Disney Pictures | false | false |
| 45 | - | Irina Palm | $40 | - | 1 | - | $40 | $43,250 | 11 | Alfa Films | false | false |
| 46 | - | Hellboy II: The Golden Army | $35 | - | 1 | - | $35 | $281,956 | 9 | United International Pictures | false | false |
| 47 | - | Social Genocide | $9 | - | 1 | - | $9 | $50,655 | 247 | Distribution Company | false | false |
| 48 | - | The Diving Bell and the Butterfly | $6 | - | 1 | - | $6 | $105,015 | 17 | Alfa Films | false | false |
