| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Mr. Bones 2: Back from the Past | $625,623 | - | 110 | - | $5,687 | $625,623 | 1 | United International Pictures | true | false |
| 2 | 1 | Quantum of Solace | $250,325 | -36.1% | 92 | -1 | $2,720 | $1,040,427 | 2 | Ster-Kinekor Pictures | false | false |
| 3 | 2 | High School Musical 3: Senior Year | $63,223 | -3.6% | 76 | -1 | $831 | $1,116,534 | 5 | Ster-Kinekor Pictures | false | false |
| 4 | 3 | Wild Child | $47,391 | +5.8% | 45 | - | $1,053 | $199,464 | 3 | United International Pictures | false | false |
| 5 | 4 | Body of Lies | $37,616 | +4.4% | 51 | - | $737 | $324,124 | 4 | NuMetro Distribution | false | false |
| 6 | 6 | Disaster Movie | $32,100 | +50.4% | 43 | -5 | $746 | $208,030 | 4 | United International Pictures | false | false |
| 7 | 5 | Nights in Rodanthe | $22,813 | -6.1% | 43 | -1 | $530 | $336,429 | 5 | NuMetro Distribution | false | false |
| 8 | 7 | Friendship | $15,680 | -15.4% | 5 | - | $3,136 | $71,484 | 3 | NuMetro Distribution | false | false |
| 9 | 8 | Max Payne | $14,535 | -3.1% | 32 | -15 | $454 | $384,963 | 6 | NuMetro Distribution | false | false |
| 10 | 11 | Death Race | $12,387 | +26.4% | 26 | -13 | $476 | $193,839 | 5 | United International Pictures | false | false |
| 11 | 9 | Beverly Hills Chihuahua | $10,552 | -16.4% | 25 | -8 | $422 | $377,657 | 9 | Ster-Kinekor Pictures | false | false |
| 12 | 12 | My Best Friend's Girl | $10,216 | +9.8% | 20 | -7 | $510 | $540,597 | 9 | NuMetro Distribution | false | false |
| 13 | 14 | Eagle Eye | $7,391 | -0.7% | 21 | -13 | $351 | $384,018 | 7 | United International Pictures | false | false |
| 14 | 15 | Quarantine | $6,392 | +7.1% | 13 | -2 | $491 | $33,181 | 3 | Ster-Kinekor Pictures | false | false |
| 15 | 13 | Mamma Mia! | $6,197 | -29.1% | 16 | -17 | $387 | $2,513,158 | 14 | United International Pictures | false | false |
| 16 | 10 | Yuvvraaj | $6,028 | -43.2% | 7 | - | $861 | $19,977 | 2 | NuMetro Distribution | false | false |
| 17 | - | The Stone Angel | $6,000 | - | 7 | - | $857 | $6,000 | 1 | Ster-Kinekor Pictures | true | false |
| 18 | 16 | The Counterfeiters | $4,975 | -3.4% | 4 | - | $1,243 | $36,603 | 4 | Ster-Kinekor Pictures | false | false |
| 19 | 23 | Lakeview Terrace | $4,849 | +102.6% | 9 | -2 | $538 | $121,079 | 6 | Ster-Kinekor Pictures | false | false |
| 20 | 19 | Righteous Kill | $4,582 | +32.5% | 7 | -6 | $654 | $171,187 | 7 | NuMetro Distribution | false | false |
| 21 | 21 | Scar | $3,342 | +13.7% | 6 | -3 | $557 | $35,248 | 5 | NuMetro Distribution | false | false |
| 22 | 17 | The Band's Visit | $3,258 | -12% | 5 | - | $651 | $36,054 | 5 | Ster-Kinekor Pictures | false | false |
| 23 | 25 | Open Season 2 | $3,094 | +80.6% | 6 | +1 | $515 | $240,759 | 10 | N/A | false | false |
| 24 | 24 | Gangster's Paradise: Jerusalema | $1,896 | +1.6% | 9 | -2 | $210 | $414,299 | 14 | United International Pictures | false | false |
| 25 | 26 | Fugitive Pieces | $1,793 | +19.9% | 2 | - | $896 | $10,786 | 5 | United International Pictures | false | false |
| 26 | 27 | Pineapple Express | $563 | -45.1% | 2 | -1 | $281 | $31,092 | 5 | Ster-Kinekor Pictures | false | false |
| 27 | 29 | Step Brothers | $498 | +53.2% | 2 | - | $249 | $39,984 | 8 | Ster-Kinekor Pictures | false | false |
| 28 | 28 | The House Bunny | $401 | -18% | 2 | -1 | $200 | $380,411 | 10 | Ster-Kinekor Pictures | false | false |
| 29 | 30 | Hellboy II: The Golden Army | $105 | -4.5% | 1 | - | $105 | $291,131 | 11 | United International Pictures | false | false |
