| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | Max Payne | $18,000,000 | $17,639,849 | -$360,151 | -2% | 3,376 | $18,000,000 | $17,639,849 | 1 | Twentieth Century Fox | - |
| 2 | 2 | - | Beverly Hills Chihuahua | $11,200,000 | $11,422,425 | +$222,425 | +2% | 3,239 | $69,067,000 | $69,282,560 | 3 | Walt Disney Studios Motion Pictures | - |
| 3 | 3 | - | The Secret Life of Bees | $11,050,000 | $10,527,799 | -$522,201 | -4.7% | 1,591 | $11,050,000 | $10,527,799 | 1 | Fox Searchlight Pictures | - |
| 4 | 4 | - | W. | $10,550,000 | $10,505,668 | -$44,332 | -0.4% | 2,030 | $10,550,000 | $10,505,668 | 1 | Lionsgate | - |
| 5 | 5 | - | Eagle Eye | $7,343,000 | $7,029,718 | -$313,282 | -4.3% | 3,326 | $81,335,000 | $81,021,825 | 4 | DreamWorks | - |
| 6 | 6 | - | Body of Lies | $6,880,000 | $6,824,259 | -$55,741 | -0.8% | 2,714 | $24,481,000 | $24,424,928 | 2 | Warner Bros. | - |
| 7 | 7 | - | Quarantine | $6,300,000 | $6,084,580 | -$215,420 | -3.4% | 2,463 | $24,687,000 | $24,471,512 | 2 | Screen Gems | - |
| 8 | 8 | - | Nick and Norah's Infinite Playlist | $3,900,000 | $3,693,384 | -$206,616 | -5.3% | 2,241 | $26,707,000 | $26,500,875 | 3 | Sony Pictures Releasing | - |
| 9 | 9 | - | Sex Drive | $3,566,000 | $3,607,164 | +$41,164 | +1.2% | 2,421 | $3,566,000 | $3,607,164 | 1 | Summit Entertainment | - |
| 10 | 10 | - | Nights in Rodanthe | $2,680,000 | $2,657,440 | -$22,560 | -0.8% | 2,115 | $36,892,000 | $36,869,470 | 4 | Warner Bros. | - |
| 11 | 11 | - | Fireproof | $2,675,000 | $2,578,271 | -$96,729 | -3.6% | 905 | $20,725,000 | $20,628,110 | 4 | The Samuel Goldwyn Company | - |
| 12 | 12 | - | The Express | $2,276,000 | $2,191,810 | -$84,190 | -3.7% | 2,810 | $8,299,000 | $8,214,570 | 2 | Universal Pictures | - |
| 13 | 13 | - | The Duchess | $2,209,000 | $2,121,588 | -$87,412 | -4% | 1,207 | $9,216,000 | $9,128,899 | 5 | Paramount Vantage | - |
| 14 | 14 | - | Appaloosa | $1,985,000 | $2,029,200 | +$44,200 | +2.2% | 1,265 | $14,282,000 | $14,326,286 | 5 | Warner Bros. | - |
| 15 | 15 | - | City of Ember | $1,725,000 | $1,730,755 | +$5,755 | +0.3% | 2,023 | $5,921,000 | $5,926,753 | 2 | Twentieth Century Fox | - |
| 16 | 16 | - | Religulous | $1,450,000 | $1,446,221 | -$3,779 | -0.3% | 540 | $9,072,000 | $9,068,325 | 3 | Lionsgate | - |
| 17 | 17 | - | Lakeview Terrace | $1,225,000 | $1,153,588 | -$71,412 | -5.8% | 1,157 | $38,300,000 | $38,228,466 | 5 | Screen Gems | - |
| 18 | 18 | - | Burn After Reading | $1,098,000 | $1,097,546 | -$454 | <0.1% | 708 | $57,114,000 | $57,118,919 | 6 | Focus Features | - |
| 19 | 19 | - | Rachel Getting Married | $722,000 | $657,646 | -$64,354 | -8.9% | 69 | $1,757,000 | $1,693,047 | 3 | Sony Pictures Classics | - |
| 20 | 20 | - | The Dark Knight | $425,000 | $412,148 | -$12,852 | -3% | 290 | $527,369,000 | $527,356,352 | 14 | Warner Bros. | - |
| 21 | 21 | - | An American Carol | $365,000 | - | - | - | 599 | $6,791,000 | - | 3 | Vivendi Entertainment | - |
| 22 | 22 | - | The Family That Preys | $335,000 | $362,063 | +$27,063 | +8.1% | 325 | $36,993,000 | $37,019,849 | 6 | Lionsgate | - |
| 23 | 25 | +2 | Igor | $234,000 | $242,231 | +$8,231 | +3.5% | 543 | $18,540,000 | $18,547,870 | 5 | Metro-Goldwyn-Mayer (MGM) | - |
| 24 | 26 | +2 | Ghost Town | $220,000 | $207,491 | -$12,509 | -5.7% | 252 | $12,901,000 | $12,888,414 | 5 | DreamWorks | - |
| 25 | 28 | +3 | What Just Happened | $216,000 | $192,508 | -$23,492 | -10.9% | 36 | $216,000 | $192,508 | 1 | Magnolia Pictures | - |
| 26 | 27 | +1 | Righteous Kill | $201,000 | $193,591 | -$7,409 | -3.7% | 381 | $39,236,000 | $39,228,389 | 6 | Overture Films | - |
| 27 | 29 | +2 | Vicky Cristina Barcelona | $179,000 | $182,297 | +$3,297 | +1.8% | 109 | $21,751,000 | $21,754,183 | 10 | Metro-Goldwyn-Mayer (MGM) | - |
| 28 | 30 | +2 | Mamma Mia! | $176,000 | $168,730 | -$7,270 | -4.1% | 219 | - | $143,328,710 | 14 | Universal Pictures | - |
| 29 | 31 | +2 | My Best Friend's Girl | $160,000 | $152,163 | -$7,837 | -4.9% | 206 | $19,160,000 | $19,151,864 | 5 | Lionsgate | - |
| 30 | 32 | +2 | Flash of Genius | $143,000 | $138,375 | -$4,625 | -3.2% | 225 | $4,239,000 | $4,234,040 | 3 | Universal Pictures | - |
| 31 | 34 | +3 | Morning Light | $134,000 | $129,295 | -$4,705 | -3.5% | 55 | $134,000 | $129,295 | 1 | Walt Disney Studios Motion Pictures | - |
| 32 | 33 | +1 | RocknRolla | $131,000 | $134,261 | +$3,261 | +2.5% | 22 | $401,000 | $404,474 | 2 | Warner Bros. | - |
| 33 | 35 | +2 | Happy-Go-Lucky | $110,000 | $107,947 | -$2,053 | -1.9% | 9 | $219,000 | $217,388 | 2 | Miramax | - |
| 34 | 39 | +5 | Tropic Thunder | $93,000 | $89,265 | -$3,735 | -4% | 179 | $110,000 | $109,876,133 | 10 | DreamWorks | - |
| 35 | 56 | +21 | How to Lose Friends & Alienate People | $37,000 | $35,948 | -$1,052 | -2.8% | 122 | $2,727,000 | $2,725,950 | 3 | Metro-Goldwyn-Mayer (MGM) | - |
| 36 | 51 | +15 | Fly Me to the Moon 3D | $36,000 | $42,949 | +$6,949 | +19.3% | 53 | $12,079,000 | $12,085,870 | 10 | Summit Entertainment | - |
| 37 | 40 | +3 | Disaster Movie | $35,000 | $57,188 | +$22,188 | +63.4% | 111 | $14,152,000 | $14,174,654 | 8 | Lionsgate | - |
| 38 | 53 | +15 | Bangkok Dangerous | $35,000 | $37,255 | +$2,255 | +6.4% | 104 | $15,277,000 | $15,279,680 | 7 | Lionsgate | - |
| 39 | 58 | +19 | Elegy | $33,200 | $33,239 | +$39 | +0.1% | 37 | $3,510,000 | $3,510,091 | 11 | The Samuel Goldwyn Company | - |
| 40 | 62 | +22 | Transsiberian | $22,000 | $20,730 | -$1,270 | -5.8% | 22 | $2,123,000 | $2,121,376 | 14 | First Look International | - |
| 41 | 65 | +24 | Ashes of Time | $18,600 | $18,175 | -$425 | -2.3% | 9 | $51,100 | $50,619 | 2 | Sony Pictures Classics | - |
| 42 | 68 | +26 | Bottle Shock | $12,900 | $13,719 | +$819 | +6.3% | 19 | $4,040,000 | $4,040,588 | 11 | Freestyle Releasing | - |
| 43 | 69 | +26 | Hounddog | $12,600 | $12,825 | +$225 | +1.8% | 5 | $78,600 | $78,811 | 5 | Empire Pictures Inc. | - |
| 44 | 77 | +33 | The Longshots | $8,000 | $8,055 | +$55 | +0.7% | 19 | $11,335,000 | $11,335,513 | 9 | Metro-Goldwyn-Mayer (MGM) | - |
| 45 | 81 | +36 | Frontrunners | $7,400 | $6,888 | -$512 | -6.9% | 1 | $10,500 | $10,011 | 1 | Oscilloscope | - |
| 46 | 87 | +41 | Flow: For Love of Water | $5,500 | $5,094 | -$406 | -7.4% | 6 | $110,000 | $110,065 | 31 | Oscilloscope | - |
