| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | Mamma Mia! | $97,001 | -40.4% | 95 | +10 | $1,021 | $2,172,453 | 7 | United International Pictures | false | false |
| 2 | 1 | My Best Friend's Girl | $68,016 | -58.3% | 51 | - | $1,333 | $263,318 | 2 | NuMetro Distribution | false | false |
| 3 | 3 | Beverly Hills Chihuahua | $49,440 | -54.9% | 40 | - | $1,236 | $164,023 | 2 | Ster-Kinekor Pictures | false | false |
| 4 | - | Superhero Movie | $49,371 | - | 40 | - | $1,234 | $49,371 | 1 | Ster-Kinekor Pictures | true | false |
| 5 | - | Bangkok Dangerous | $49,276 | - | 30 | - | $1,642 | $49,276 | 1 | NuMetro Distribution | true | false |
| 6 | 6 | Taken | $28,941 | -37.9% | 36 | -5 | $803 | $389,148 | 5 | NuMetro Distribution | false | false |
| 7 | 5 | The House Bunny | $28,864 | -50.8% | 38 | -2 | $759 | $276,393 | 3 | Ster-Kinekor Pictures | false | false |
| 8 | 4 | Hansie: A True Story | $26,895 | -61.2% | 63 | -22 | $426 | $371,855 | 3 | NuMetro Distribution | false | false |
| 9 | 7 | Open Season 2 | $21,329 | -54.2% | 26 | - | $820 | $216,852 | 3 | N/A | false | false |
| 10 | 10 | Gangster's Paradise: Jerusalema | $18,769 | -33.5% | 13 | -1 | $1,443 | $364,742 | 7 | United International Pictures | false | false |
| 11 | - | Brideshead Revisited | $15,472 | - | 10 | - | $1,547 | $15,472 | 1 | Ster-Kinekor Pictures | true | false |
| 12 | 8 | Space Chimps | $13,036 | -69.1% | 43 | -5 | $303 | $287,076 | 4 | United International Pictures | false | false |
| 13 | 9 | Hellboy II: The Golden Army | $12,972 | -68.9% | 36 | -14 | $360 | $315,775 | 4 | United International Pictures | false | false |
| 14 | 11 | Babylon A.D. | $12,650 | -51.1% | 31 | -2 | $408 | $291,428 | 6 | NuMetro Distribution | false | false |
| 15 | 14 | In Bruges | $10,468 | -30.2% | 10 | - | $1,046 | $87,360 | 4 | Ster-Kinekor Pictures | false | false |
| 16 | - | Step Brothers | $9,031 | - | 10 | - | $903 | $9,031 | 1 | Ster-Kinekor Pictures | true | false |
| 17 | 12 | Tropic Thunder | $8,287 | -56.3% | 21 | -1 | $394 | $325,095 | 6 | United International Pictures | false | false |
| 18 | 15 | Before the Rains | $8,191 | -37.7% | 10 | - | $819 | $25,399 | 2 | United International Pictures | false | false |
| 19 | - | The Love Guru | $7,118 | - | 10 | - | $711 | $7,118 | 1 | United International Pictures | true | false |
| 20 | - | Hello | $4,459 | - | 4 | - | $1,114 | $5,442 | 1 | Ster-Kinekor Pictures | true | false |
| 21 | 13 | Star Wars: The Clone Wars | $4,150 | -77.6% | 19 | -16 | $218 | $83,902 | 3 | NuMetro Distribution | false | false |
| 22 | 16 | The Legend of Drona | $3,716 | -68.6% | 7 | - | $530 | $16,267 | 2 | NuMetro Distribution | false | false |
| 23 | 18 | The Dark Knight | $3,627 | -63.8% | 8 | -5 | $453 | $1,787,300 | 12 | NuMetro Distribution | false | false |
| 24 | 20 | College Road Trip | $2,837 | -44.8% | 7 | - | $405 | $641,090 | 17 | Ster-Kinekor Pictures | false | false |
| 25 | 21 | Prom Night | $1,684 | -41.6% | 5 | -3 | $336 | $129,501 | 8 | Ster-Kinekor Pictures | false | false |
| 26 | 19 | The Mummy: Tomb of the Dragon Emperor | $1,535 | -78.7% | 11 | -3 | $139 | $764,657 | 10 | United International Pictures | false | false |
| 27 | 25 | Hancock | $684 | -46.8% | 1 | -2 | $684 | $2,135,743 | 15 | Ster-Kinekor Pictures | false | false |
| 28 | 22 | You Don't Mess with the Zohan | $282 | -86.6% | 2 | -4 | $141 | $673,448 | 11 | Ster-Kinekor Pictures | false | false |
