| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | Tropic Thunder | $11,500,000 | $11,518,611 | +$18,611 | +0.2% | 3,473 | $83,834,000 | $83,852,435 | 3 | DreamWorks | - |
| 2 | 2 | - | Babylon A.D. | $9,700,000 | $9,484,627 | -$215,373 | -2.2% | 3,390 | $9,700,000 | $9,484,627 | 1 | Twentieth Century Fox | - |
| 3 | 3 | - | The Dark Knight | $8,750,000 | $8,622,879 | -$127,121 | -1.5% | 2,750 | $502,421,000 | $502,293,926 | 7 | Warner Bros. | - |
| 4 | 4 | - | The House Bunny | $8,300,000 | $8,317,426 | +$17,426 | +0.2% | 2,714 | $27,851,000 | $27,868,669 | 2 | Sony Pictures Releasing | - |
| 5 | 5 | - | Traitor | $7,900,000 | $7,868,465 | -$31,535 | -0.4% | 2,054 | $9,401,000 | $9,369,792 | 1 | Overture Films | - |
| 6 | 6 | - | Death Race | $6,228,000 | $6,304,635 | +$76,635 | +1.2% | 2,537 | $23,078,000 | $23,154,165 | 2 | Universal Pictures | - |
| 7 | 7 | - | Disaster Movie | $6,170,000 | $5,836,973 | -$333,027 | -5.4% | 2,642 | $6,170,000 | $5,836,973 | 1 | Lionsgate | - |
| 8 | 8 | - | Mamma Mia! | $4,418,000 | $4,211,495 | -$206,505 | -4.7% | 1,968 | - | $131,302,175 | 7 | Universal Pictures | - |
| 9 | 9 | - | Pineapple Express | $3,390,000 | $3,535,220 | +$145,220 | +4.3% | 2,047 | $79,773,000 | $79,918,601 | 4 | Sony Pictures Releasing | - |
| 10 | 10 | - | Vicky Cristina Barcelona | $3,003,000 | $2,815,506 | -$187,494 | -6.2% | 692 | $12,787,000 | $12,599,417 | 3 | Metro-Goldwyn-Mayer (MGM) | - |
| 11 | 12 | +1 | Star Wars: The Clone Wars | $2,900,000 | $2,711,145 | -$188,855 | -6.5% | 2,444 | $29,808,000 | $29,619,167 | 3 | Warner Bros. | - |
| 12 | 11 | -1 | Mirrors | $2,825,000 | $2,751,301 | -$73,699 | -2.6% | 1,820 | $24,893,000 | $24,819,581 | 3 | Twentieth Century Fox | - |
| 13 | 13 | - | The Mummy: Tomb of the Dragon Emperor | $2,595,000 | $2,629,445 | +$34,445 | +1.3% | 1,713 | $97,824,000 | $97,858,315 | 5 | Universal Pictures | - |
| 14 | 14 | - | The Longshots | $2,406,000 | $2,310,498 | -$95,502 | -4% | 2,089 | $7,556,000 | $7,460,122 | 2 | Metro-Goldwyn-Mayer (MGM) | - |
| 15 | 15 | - | College | $2,105,000 | $2,153,109 | +$48,109 | +2.3% | 2,123 | $2,105,000 | $2,153,109 | 1 | Metro-Goldwyn-Mayer (MGM) | - |
| 16 | 16 | - | Journey to the Center of the Earth | $1,800,000 | $1,773,815 | -$26,185 | -1.5% | 801 | $94,579,000 | $94,553,075 | 8 | Warner Bros. | - |
| 17 | 17 | - | Hamlet 2 | $1,680,000 | $1,698,820 | +$18,820 | +1.1% | 1,597 | $2,686,000 | $2,725,020 | 2 | Focus Features | - |
| 18 | 18 | - | Fly Me to the Moon 3D | $1,600,000 | $1,509,198 | -$90,802 | -5.7% | 630 | $6,333,000 | $6,242,261 | 3 | Summit Entertainment | - |
| 19 | 19 | - | The Sisterhood of the Traveling Pants 2 | $1,450,000 | $1,435,809 | -$14,191 | -1% | 1,252 | $41,122,000 | $41,108,020 | 4 | Warner Bros. | - |
| 20 | 20 | - | Step Brothers | $1,255,000 | $1,357,288 | +$102,288 | +8.2% | 1,036 | $97,824,000 | $97,926,025 | 6 | Sony Pictures Releasing | - |
| 21 | 21 | - | WALL·E | $1,112,000 | $1,175,863 | +$63,863 | +5.7% | 1,155 | $217,910,000 | $217,973,943 | 10 | Walt Disney Studios Motion Pictures | - |
| 22 | 22 | - | The Rocker | $1,000,000 | $969,878 | -$30,122 | -3% | 2,784 | $5,665,000 | $5,634,437 | 2 | Twentieth Century Fox | - |
| 23 | 25 | +2 | Elegy | $647,000 | $624,069 | -$22,931 | -3.5% | 139 | $1,577,000 | $1,553,674 | 4 | The Samuel Goldwyn Company | - |
| 24 | 26 | +2 | Bottle Shock | $529,000 | $547,225 | +$18,225 | +3.4% | 295 | $2,436,000 | $2,454,139 | 4 | Freestyle Releasing | - |
| 25 | 28 | +3 | Tell No One | $403,000 | $373,623 | -$29,377 | -7.3% | 102 | $4,313,000 | $4,283,364 | 9 | Music Box Films | - |
| 26 | 30 | +4 | Transsiberian | $293,000 | $281,949 | -$11,051 | -3.8% | 81 | $850,000 | $839,312 | 7 | First Look International | - |
| 27 | 31 | +4 | Frozen River | $287,000 | $256,749 | -$30,251 | -10.5% | 69 | $779,000 | $749,332 | 5 | Sony Pictures Classics | - |
| 28 | 34 | +6 | Brideshead Revisited | $229,000 | $218,546 | -$10,454 | -4.6% | 232 | $5,916,000 | $5,905,793 | 6 | Miramax | - |
| 29 | 35 | +6 | Hellboy II: The Golden Army | $182,000 | $166,245 | -$15,755 | -8.7% | 204 | $75,390,000 | $75,374,075 | 8 | Universal Pictures | - |
| 30 | 36 | +6 | Wanted | $177,000 | $158,105 | -$18,895 | -10.7% | 186 | $134,000,000 | $133,980,970 | 10 | Universal Pictures | - |
| 31 | 43 | +12 | The Incredible Hulk | $72,000 | $73,495 | +$1,495 | +2.1% | 100 | $134,499,000 | $134,500,425 | 12 | Universal Pictures | - |
| 32 | 48 | +16 | I Served the King of England | $53,500 | $53,218 | -$282 | -0.5% | 8 | $53,500 | $53,218 | 1 | Sony Pictures Classics | - |
| 33 | 54 | +21 | I.O.U.S.A. | $36,900 | $37,320 | +$420 | +1.1% | 21 | $696,000 | $661,135 | 2 | Roadside Attractions | - |
| 34 | 61 | +27 | Beer for My Horses | $23,500 | $26,260 | +$2,760 | +11.7% | 29 | $442,000 | $444,813 | 4 | Roadside Attractions | - |
| 35 | 77 | +42 | Sukiyaki Western Django | $10,200 | $9,856 | -$344 | -3.4% | 1 | $10,200 | $9,856 | 1 | First Look International | - |
