| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | The Dark Knight | $75,630,000 | $75,166,466 | -$463,534 | -0.6% | 4,366 | $314,245,000 | $313,781,677 | 2 | Warner Bros. | - |
| 2 | 2 | - | Step Brothers | $30,000,000 | $30,940,732 | +$940,732 | +3.1% | 3,094 | $30,000,000 | $30,940,732 | 1 | Sony Pictures Releasing | - |
| 3 | 3 | - | Mamma Mia! | $17,865,000 | $17,746,725 | -$118,275 | -0.7% | 2,990 | - | $62,595,465 | 2 | Universal Pictures | - |
| 4 | 4 | - | The X Files: I Want to Believe | $10,200,000 | $10,021,753 | -$178,247 | -1.7% | 3,185 | $10,200,000 | $10,021,753 | 1 | Twentieth Century Fox | - |
| 5 | 5 | - | Journey to the Center of the Earth | $9,415,000 | $9,717,217 | +$302,217 | +3.2% | 2,688 | $60,185,000 | $60,487,455 | 3 | Warner Bros. | - |
| 6 | 6 | - | Hancock | $8,200,000 | $8,311,123 | +$111,123 | +1.4% | 3,309 | $206,371,000 | $206,482,007 | 4 | Sony Pictures Releasing | - |
| 7 | 7 | - | WALL·E | $6,349,000 | $6,422,186 | +$73,186 | +1.2% | 3,044 | $195,235,000 | $195,308,076 | 5 | Walt Disney Studios Motion Pictures | - |
| 8 | 8 | - | Hellboy II: The Golden Army | $4,934,000 | $5,100,305 | +$166,305 | +3.4% | 3,018 | $65,894,000 | $66,059,925 | 3 | Universal Pictures | - |
| 9 | 9 | - | Space Chimps | $4,375,000 | $4,536,838 | +$161,838 | +3.7% | 2,538 | $16,006,000 | $16,167,380 | 2 | Twentieth Century Fox | - |
| 10 | 10 | - | Wanted | $2,727,000 | $2,738,550 | +$11,550 | +0.4% | 1,750 | $128,616,000 | $128,627,405 | 5 | Universal Pictures | - |
| 11 | 11 | - | Get Smart | $2,300,000 | $2,272,394 | -$27,606 | -1.2% | 1,420 | $124,214,000 | $124,186,385 | 6 | Warner Bros. | - |
| 12 | 12 | - | Kung Fu Panda | $1,030,000 | $1,055,932 | +$25,932 | +2.5% | 917 | $208,972,000 | $208,997,686 | 8 | DreamWorks | - |
| 13 | 13 | - | Kit Kittredge: An American Girl | $593,000 | $601,888 | +$8,888 | +1.5% | 535 | $15,267,000 | $15,275,168 | 6 | Picturehouse | - |
| 14 | 14 | - | Indiana Jones and the Kingdom of the Crystal Skull | $550,000 | $570,774 | +$20,774 | +3.8% | 477 | $313,626,000 | $313,646,685 | 10 | Paramount Pictures | - |
| 15 | 15 | - | Sex and the City | $460,000 | $447,444 | -$12,556 | -2.7% | 347 | $150,854,000 | $150,841,566 | 9 | Warner Bros. | - |
| 16 | 17 | +1 | Tell No One | $430,000 | $421,821 | -$8,179 | -1.9% | 77 | $1,661,000 | $1,653,434 | 4 | Music Box Films | - |
| 17 | 16 | -1 | The Incredible Hulk | $425,000 | $423,150 | -$1,850 | -0.4% | 403 | $132,543,000 | $132,541,330 | 7 | Universal Pictures | - |
| 18 | 19 | +1 | Meet Dave | $375,000 | $381,469 | +$6,469 | +1.7% | 488 | $10,833,000 | $10,839,801 | 3 | Twentieth Century Fox | - |
| 19 | 21 | +2 | Brideshead Revisited | $332,000 | $339,616 | +$7,616 | +2.3% | 33 | $332,000 | $339,616 | 1 | Miramax | - |
| 20 | 22 | +2 | Iron Man | $289,000 | $310,654 | +$21,654 | +7.5% | 274 | $314,905,000 | $314,925,955 | 13 | Paramount Pictures | - |
| 21 | 23 | +2 | The Wackness | $241,000 | $232,940 | -$8,060 | -3.3% | 120 | $1,072,000 | $1,063,920 | 4 | Sony Pictures Classics | - |
| 22 | 25 | +3 | Mongol: The Rise of Genghis Khan | $165,000 | $163,137 | -$1,863 | -1.1% | 144 | $5,174,000 | $5,171,878 | 8 | Picturehouse | - |
| 23 | 33 | +10 | Brick Lane | $62,200 | $60,856 | -$1,344 | -2.2% | 49 | $653,000 | $651,182 | 6 | Sony Pictures Classics | - |
| 24 | 37 | +13 | Man on Wire | $48,000 | $51,392 | +$3,392 | +7.1% | 2 | $48,000 | $51,392 | 1 | Magnolia Pictures | - |
| 25 | 40 | +15 | American Teen | $42,800 | $45,589 | +$2,789 | +6.5% | 5 | $42,800 | $45,589 | 1 | Paramount Vantage | - |
| 26 | 42 | +16 | CSNY/Déjà Vu | $36,100 | $33,997 | -$2,103 | -5.8% | 24 | $36,100 | $33,997 | 1 | Roadside Attractions | - |
| 27 | 41 | +14 | The Love Guru | $36,000 | $38,552 | +$2,552 | +7.1% | 107 | $31,891,000 | $31,893,310 | 6 | Paramount Pictures | - |
| 28 | 48 | +20 | Before the Rains | $32,850 | $31,432 | -$1,418 | -4.3% | 23 | $910,000 | $908,875 | 12 | Roadside Attractions | - |
| 29 | 52 | +23 | Transsiberian | $26,500 | $26,560 | +$60 | +0.2% | 2 | $80,000 | $80,086 | 2 | First Look International | - |
| 30 | 55 | +25 | The Fall | $19,500 | $22,522 | +$3,022 | +15.5% | 31 | $2,140,000 | $2,143,469 | 12 | Roadside Attractions | - |
| 31 | 59 | +28 | War, Inc. | $17,400 | $16,469 | -$931 | -5.4% | 25 | $566,000 | $564,605 | 10 | First Look International | - |
| 32 | 63 | +31 | Baghead | $17,200 | $15,709 | -$1,491 | -8.7% | 7 | $49,200 | $47,741 | 7 | Sony Pictures Classics | - |
| 33 | 67 | +34 | Boy A | $11,400 | $13,024 | +$1,624 | +14.2% | 2 | $13,100 | $14,746 | 1 | The Weinstein Company | - |
| 34 | 90 | +56 | Lou Reed's Berlin | $4,070 | $3,784 | -$286 | -7% | 2 | $19,000 | $18,757 | 2 | Third Rail Releasing | - |
