| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Hancock | $930,158 | -34.1% | 91 | +1 | $10,221 | $3,102,582 | 2 | Sony Pictures Releasing | false | false |
| 2 | - | Mamma Mia! | $917,514 | - | 106 | - | $8,655 | $1,424,518 | 1 | Universal Pictures International (UPI) | true | false |
| 3 | 2 | Kung Fu Panda | $899,238 | -5.2% | 189 | - | $4,757 | $3,233,142 | 2 | Universal Pictures International (UPI) | false | false |
| 4 | - | De brief voor de koning | $404,599 | - | 103 | - | $3,928 | $501,749 | 1 | Benelux Film Distributors | true | false |
| 5 | 3 | The Chronicles of Narnia: Prince Caspian | $311,611 | -31.2% | 174 | -2 | $1,790 | $2,297,720 | 3 | Walt Disney Pictures | false | false |
| 6 | 4 | Sex and the City | $293,886 | -29.1% | 100 | -8 | $2,938 | $5,315,059 | 6 | Paradiso Entertainment | false | false |
| 7 | 5 | Hoe overleef ik...? | $182,136 | -31% | 93 | - | $1,958 | $1,894,810 | 4 | Warner Bros. | false | false |
| 8 | - | The Strangers | $178,454 | - | 35 | - | $5,098 | $219,613 | 1 | RCV Film Distribution | true | false |
| 9 | 6 | Indiana Jones and the Kingdom of the Crystal Skull | $151,380 | -21.7% | 64 | -28 | $2,365 | $6,577,936 | 9 | Universal Pictures International (UPI) | false | false |
| 10 | 8 | Snuf de hond in oorlogstijd | $95,010 | -1.2% | 64 | - | $1,484 | $510,789 | 4 | RCV Film Distribution | false | false |
| 11 | 7 | 21 | $94,872 | -31.5% | 40 | -9 | $2,371 | $1,088,379 | 4 | Sony Pictures Releasing | false | false |
| 12 | 10 | I've Loved You So Long | $61,602 | -0.8% | 19 | -1 | $3,242 | $591,332 | 7 | Benelux Film Distributors | false | false |
| 13 | 14 | Into the Wild | $53,704 | +0.5% | 20 | - | $2,685 | $1,151,934 | 13 | A-Film Distribution | false | false |
| 14 | 9 | What Happens in Vegas | $41,361 | -34% | 22 | -16 | $1,880 | $4,176,139 | 11 | Warner Bros. | false | false |
| 15 | 15 | In Bruges | $39,742 | +7.9% | 14 | +1 | $2,838 | $257,861 | 4 | Universal Pictures International (UPI) | false | false |
| 16 | 16 | De kabouterschat | $36,247 | +9.7% | 29 | - | $1,249 | $135,760 | 3 | Independent Films | false | false |
| 17 | 12 | Forgetting Sarah Marshall | $32,120 | -47.8% | 18 | -15 | $1,784 | $354,127 | 3 | Universal Pictures International (UPI) | false | false |
| 18 | 17 | The Night of the Sunflowers | $29,827 | -0.6% | 12 | - | $2,485 | $73,085 | 2 | Benelux Film Distributors | false | false |
| 19 | 13 | The Incredible Hulk | $24,414 | -54.8% | 16 | -31 | $1,525 | $1,322,551 | 5 | Universal Pictures International (UPI) | false | false |
| 20 | 18 | Conversations with My Gardener | $24,325 | -13.1% | 9 | - | $2,702 | $115,337 | 3 | Cinéart | false | false |
| 21 | - | The Grocer's Son | $19,288 | - | 7 | - | $2,755 | $19,288 | 1 | Benelux Film Distributors | true | false |
| 22 | - | Stop-Loss | $8,384 | - | 5 | - | $1,676 | $12,518 | 1 | Universal Pictures International (UPI) | true | false |
| 23 | - | 4:30 | $586 | - | 1 | - | $586 | $586 | 1 | Filmmuseum Distributie | true | false |
