| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Wanted | $77,217 | - | 15 | - | $5,147 | $77,217 | 1 | Prooptiki | true | false |
| 2 | 1 | Sex and the City | $21,405 | -40.6% | 16 | -1 | $1,337 | $412,108 | 4 | Alexandra Films | false | false |
| 3 | 2 | Indiana Jones and the Kingdom of the Crystal Skull | $14,694 | -37.3% | 17 | -2 | $864 | $680,153 | 6 | Prooptiki | false | false |
| 4 | - | Shutter | $9,283 | - | 5 | - | $1,856 | $9,283 | 1 | Alexandra Films | true | false |
| 5 | 3 | Big Stan | $7,394 | -63.2% | 5 | - | $1,478 | $39,422 | 2 | Alexandra Films | false | false |
| 6 | 5 | The Happening | $6,962 | -52.4% | 7 | - | $994 | $81,879 | 3 | Alexandra Films | false | false |
| 7 | 4 | The Incredible Hulk | $6,159 | -61.1% | 10 | - | $615 | $82,946 | 3 | Prooptiki | false | false |
| 8 | 6 | Mongol: The Rise of Genghis Khan | $3,397 | -60.4% | 5 | - | $679 | $16,452 | 2 | Sunny Films | false | false |
| 9 | 7 | 88 Minutes | $2,307 | -53.1% | 5 | - | $461 | $80,737 | 5 | Alexandra Films | false | false |
| 10 | 9 | Horton Hears a Who! | $2,116 | -24.9% | 7 | -1 | $302 | $182,696 | 10 | Alexandra Films | false | false |
| 11 | 8 | My Blueberry Nights | $1,560 | -56.2% | 4 | - | $390 | $23,087 | 3 | Sunny Films | false | false |
| 12 | 10 | What Happens in Vegas | $984 | -63% | 4 | -3 | $246 | $175,291 | 7 | Alexandra Films | false | false |
| 13 | 11 | Love in the Time of Cholera | $866 | -34.6% | 3 | -1 | $288 | $26,394 | 5 | Prooptiki | false | false |
| 14 | 12 | Iron Man | $196 | -65.4% | 3 | -2 | $65 | $156,062 | 9 | Prooptiki | false | false |
| 15 | 15 | Speed Racer | $143 | -37.8% | 3 | -3 | $47 | $18,335 | 7 | Alexandra Films | false | false |
| 16 | - | Michael Clayton | $96 | - | 1 | - | $96 | $95,268 | 18 | Sunny Films | false | false |
| 17 | - | Forgetting Sarah Marshall | $95 | - | 2 | - | $47 | $43,940 | 10 | Prooptiki | false | false |
| 18 | 18 | The Bucket List | $82 | -8.9% | 1 | -2 | $82 | $103,726 | 12 | Alexandra Films | false | false |
| 19 | - | National Treasure: Book of Secrets | $80 | - | 1 | - | $80 | $413,170 | 28 | Sunny Films | false | false |
| 20 | 16 | The Spiderwick Chronicles | $53 | -64.9% | 2 | - | $26 | $74,637 | 13 | Prooptiki | false | false |
| 21 | 25 | The Game Plan | $32 | +100% | 2 | +1 | $16 | $84,214 | 15 | Sunny Films | false | false |
| 22 | 20 | The Eye | $29 | -61.3% | 1 | - | $29 | $40,920 | 10 | Alexandra Films | false | false |
| 23 | - | Mad Money | $20 | - | 2 | - | $10 | $35,684 | 11 | Sunny Films | false | false |
| 24 | - | Elizabeth: The Golden Age | $16 | - | 1 | - | $16 | $69,349 | 31 | Prooptiki | false | false |
| 25 | 21 | 21 | $16 | -76.5% | 1 | -2 | $16 | $126,661 | 8 | Alexandra Films | false | false |
| 26 | 14 | Surviving with Wolves | $13 | -95.5% | 3 | -1 | $4 | $6,475 | 5 | Sunny Films | false | false |
| 27 | - | The Singer (Quand j'étais chanteur) | $8 | - | 1 | - | $8 | $10,289 | 34 | Alexandra Films | false | false |
| 28 | - | No Country for Old Men | $8 | - | 1 | - | $8 | $80,697 | 19 | Prooptiki | false | false |
| 29 | - | The Nanny Diaries | $5 | - | 1 | - | $5 | $23,874 | 32 | Sunny Films | false | false |
