| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Sex and the City | $145,152 | -63.4% | 75 | -14 | $1,935 | $2,829,942 | 4 | Warner Bros. | false | false |
| 2 | 2 | Indiana Jones and the Kingdom of the Crystal Skull | $110,711 | -68.5% | 91 | +18 | $1,216 | $5,141,225 | 5 | Universal Pictures International (UPI) | false | false |
| 3 | 3 | The Happening | $73,005 | -68.3% | 48 | - | $1,520 | $349,317 | 2 | 20th Century Fox International | false | false |
| 4 | 4 | 21 | $55,204 | -66.7% | 33 | - | $1,672 | $498,305 | 3 | Walt Disney Pictures | false | false |
| 5 | 5 | Forgetting Sarah Marshall | $44,872 | -66.8% | 30 | - | $1,495 | $216,849 | 2 | Universal Pictures International (UPI) | false | false |
| 6 | 10 | Made of Honor | $43,798 | +61.5% | 31 | +8 | $1,412 | $742,210 | 6 | Walt Disney Pictures | false | false |
| 7 | 6 | What Happens in Vegas | $17,175 | -63% | 20 | - | $858 | $2,084,650 | 7 | 20th Century Fox International | false | false |
| 8 | 7 | The Nanny Diaries | $13,613 | -60.3% | 8 | -1 | $1,701 | $61,409 | 2 | Ascot Elite Entertainment Group | false | false |
| 9 | 8 | The Wave | $10,121 | -68% | 23 | +2 | $440 | $809,276 | 8 | Rialto Distribution | false | false |
| 10 | - | Dan in Real Life | $9,659 | - | 9 | - | $1,073 | $9,659 | 1 | Warner Bros. | true | false |
| 11 | - | The Incredible Hulk | $7,556 | - | 4 | - | $1,889 | $8,898 | 1 | Universal Pictures International (UPI) | true | false |
| 12 | - | Speed Racer | $6,510 | - | 5 | - | $1,302 | $67,752 | 7 | Warner Bros. | false | false |
| 13 | - | Me Two | $5,566 | - | 4 | - | $1,391 | $7,462 | 1 | Frenetic Films | true | false |
| 14 | 9 | The Game Plan | $4,654 | -83.9% | 18 | -2 | $258 | $355,291 | 8 | Walt Disney Pictures | false | false |
| 15 | - | JCVD | $4,235 | - | 5 | - | $847 | $56,272 | 3 | Pathé | false | false |
| 16 | - | Cherry Blossoms | $3,982 | - | 8 | - | $497 | $662,679 | 13 | Ascot Elite Entertainment Group | false | false |
| 17 | - | The Kite Runner | $3,779 | - | 4 | - | $944 | $2,993,004 | 23 | Universal Pictures International (UPI) | false | false |
| 18 | 11 | Once | $3,648 | -73% | 8 | - | $456 | $466,829 | 11 | Ascot Elite Entertainment Group | false | false |
| 19 | - | Welcome to the Sticks | $3,567 | - | 5 | - | $713 | $4,995,763 | 17 | Pathé | false | false |
| 20 | - | Molière | $3,161 | - | 4 | - | $790 | $180,243 | 73 | Frenetic Films | false | false |
| 21 | - | Zu Fuss nach Santiago de Compostela | $3,026 | - | 8 | - | $378 | $363,496 | 34 | Frenetic Films | false | false |
| 22 | - | Lemon Tree | $2,932 | - | 5 | - | $586 | $146,528 | 8 | Agora Films | false | false |
| 23 | - | Touch the Sky | $2,641 | - | 3 | - | $880 | $14,197 | 1 | Filmcoopi | true | false |
| 24 | - | Days and Clouds | $2,553 | - | 4 | - | $638 | $451,278 | 34 | Filmcoopi | false | false |
| 25 | - | A Christmas Tale | $2,237 | - | 2 | - | $1,118 | $86,038 | 5 | JMH Distribution | false | false |
| 26 | 12 | Iron Man | $1,930 | -49.5% | 18 | +10 | $107 | $1,633,400 | 8 | Universal Pictures International (UPI) | false | false |
| 27 | 13 | The Other Boleyn Girl | $802 | -72.7% | 3 | -3 | $267 | $901,129 | 16 | Universal Pictures International (UPI) | false | false |
| 28 | 14 | No Country for Old Men | $495 | -62.7% | 2 | - | $247 | $2,209,665 | 22 | Universal Pictures International (UPI) | false | false |
| 29 | 15 | Superhero Movie | $178 | -85.8% | 1 | - | $178 | $26,588 | 6 | Ascot Elite Entertainment Group | false | false |
