| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Sex and the City | $36,032 | -54% | 17 | +1 | $2,119 | $364,476 | 3 | Alexandra Films | false | false |
| 2 | 2 | Indiana Jones and the Kingdom of the Crystal Skull | $23,424 | -59% | 19 | - | $1,232 | $646,076 | 5 | Prooptiki | false | false |
| 3 | - | Big Stan | $20,114 | - | 5 | - | $4,022 | $20,114 | 1 | Alexandra Films | true | false |
| 4 | 4 | The Incredible Hulk | $15,844 | -51.6% | 10 | +1 | $1,584 | $66,813 | 2 | Prooptiki | false | false |
| 5 | 3 | The Happening | $14,614 | -55.7% | 7 | - | $2,087 | $64,085 | 2 | Alexandra Films | false | false |
| 6 | - | Mongol: The Rise of Genghis Khan | $8,574 | - | 5 | - | $1,714 | $8,574 | 1 | Sunny Films | true | false |
| 7 | 7 | 88 Minutes | $4,916 | -35% | 5 | - | $983 | $74,602 | 4 | Alexandra Films | false | false |
| 8 | 5 | My Blueberry Nights | $3,562 | -68% | 4 | - | $890 | $19,224 | 2 | Sunny Films | false | false |
| 9 | 8 | Horton Hears a Who! | $2,817 | -49.6% | 8 | -1 | $352 | $178,012 | 9 | Alexandra Films | false | false |
| 10 | 6 | What Happens in Vegas | $2,659 | -70.9% | 7 | - | $379 | $171,375 | 6 | Alexandra Films | false | false |
| 11 | 9 | Love in the Time of Cholera | $1,325 | -47.5% | 4 | - | $331 | $24,180 | 4 | Prooptiki | false | false |
| 12 | 12 | Iron Man | $566 | -9.9% | 5 | +3 | $113 | $153,756 | 8 | Prooptiki | false | false |
| 13 | 13 | 99 Francs | $312 | -48.8% | 3 | - | $104 | $12,260 | 7 | Big Bang Media | false | false |
| 14 | 20 | Surviving with Wolves | $286 | +183.2% | 4 | - | $71 | $6,132 | 4 | Sunny Films | false | false |
| 15 | 10 | Speed Racer | $230 | -78.2% | 6 | - | $38 | $17,814 | 6 | Alexandra Films | false | false |
| 16 | 17 | The Spiderwick Chronicles | $151 | -48.3% | 2 | - | $75 | $73,784 | 12 | Prooptiki | false | false |
| 17 | 15 | In the Valley of Elah | $115 | -63.8% | 2 | -2 | $57 | $7,450 | 10 | Prooptiki | false | false |
| 18 | 18 | The Bucket List | $90 | -68.9% | 3 | -2 | $30 | $102,774 | 11 | Alexandra Films | false | false |
| 19 | - | There Will Be Blood | $80 | - | 1 | - | $80 | $24,432 | 13 | Sunny Films | false | false |
| 20 | 19 | The Eye | $75 | -43.6% | 1 | -2 | $75 | $40,470 | 9 | Alexandra Films | false | false |
| 21 | 14 | 21 | $68 | -88.5% | 3 | -4 | $22 | $124,880 | 7 | Alexandra Films | false | false |
| 22 | - | Definitely, Maybe | $39 | - | 1 | - | $39 | $19,319 | 11 | Prooptiki | false | false |
| 23 | 25 | You, the Living | $27 | +92.9% | 1 | - | $27 | $1,182 | 10 | Big Bang Media | false | false |
| 24 | 11 | Fool's Gold | $18 | -97.3% | 2 | -1 | $9 | $137,649 | 8 | Alexandra Films | false | false |
| 25 | 24 | The Game Plan | $16 | -59% | 1 | - | $16 | $83,370 | 14 | Sunny Films | false | false |
