| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | The Incredible Hulk | $54,538,000 | $55,414,050 | +$876,050 | +1.6% | 3,505 | $54,538,000 | $55,414,050 | 1 | Universal Pictures | - |
| 2 | 2 | - | Kung Fu Panda | $34,321,000 | $33,612,594 | -$708,406 | -2.1% | 4,136 | $117,998,000 | $117,289,932 | 2 | DreamWorks | - |
| 3 | 3 | - | The Happening | $30,500,000 | $30,517,109 | +$17,109 | <0.1% | 2,986 | $30,500,000 | $30,517,109 | 1 | Twentieth Century Fox | - |
| 4 | 4 | - | You Don't Mess with the Zohan | $16,400,000 | $16,370,344 | -$29,656 | -0.2% | 3,466 | $68,790,000 | $68,760,685 | 2 | Sony Pictures Releasing | - |
| 5 | 5 | - | Indiana Jones and the Kingdom of the Crystal Skull | $13,547,000 | $14,741,834 | +$1,194,834 | +8.8% | 3,804 | $275,329,000 | $276,524,265 | 4 | Paramount Pictures | - |
| 6 | 6 | - | Sex and the City | $10,185,000 | $9,788,353 | -$396,647 | -3.9% | 3,155 | $119,919,000 | $119,522,016 | 3 | Warner Bros. | - |
| 7 | 7 | - | Iron Man | $5,130,000 | $5,620,375 | +$490,375 | +9.6% | 2,403 | $297,428,000 | $297,918,329 | 7 | Paramount Pictures | - |
| 8 | 8 | - | The Strangers | $4,097,000 | $4,024,485 | -$72,515 | -1.8% | 2,410 | $45,360,000 | $45,287,220 | 3 | Rogue Pictures | - |
| 9 | 9 | - | The Chronicles of Narnia: Prince Caspian | $3,004,000 | $3,165,013 | +$161,013 | +5.4% | 2,308 | $131,744,000 | $131,904,474 | 5 | Walt Disney Studios Motion Pictures | - |
| 10 | 10 | - | What Happens in Vegas | $1,700,000 | $1,667,587 | -$32,413 | -1.9% | 1,422 | $75,788,000 | $75,755,145 | 6 | Twentieth Century Fox | - |
| 11 | 12 | +1 | The Visitor | $450,000 | $420,928 | -$29,072 | -6.5% | 254 | $6,650,000 | $6,621,330 | 10 | Overture Films | - |
| 12 | 11 | -1 | Baby Mama | $408,000 | $441,685 | +$33,685 | +8.3% | 453 | $58,763,000 | $58,797,040 | 8 | Universal Pictures | - |
| 13 | 14 | +1 | Forgetting Sarah Marshall | $311,000 | $287,625 | -$23,375 | -7.5% | 306 | $62,129,000 | $62,106,520 | 9 | Universal Pictures | - |
| 14 | 15 | +1 | Horton Hears a Who! | $185,000 | $188,736 | +$3,736 | +2% | 294 | $153,352,000 | $153,355,932 | 14 | Twentieth Century Fox | - |
| 15 | 19 | +4 | Nim's Island | $173,000 | $165,442 | -$7,558 | -4.4% | 277 | $46,702,000 | $46,694,283 | 11 | Twentieth Century Fox | - |
| 16 | 21 | +5 | Then She Found Me | $155,000 | $140,762 | -$14,238 | -9.2% | 119 | $3,035,000 | $3,020,648 | 8 | THINKFilm | - |
| 17 | 22 | +5 | The Promotion | $137,000 | $128,244 | -$8,756 | -6.4% | 81 | $181,000 | $171,307 | 2 | Third Rail Releasing | - |
| 18 | 26 | +8 | Young@Heart | $116,000 | $111,130 | -$4,870 | -4.2% | 122 | $3,317,000 | $3,311,661 | 10 | Fox Searchlight Pictures | - |
| 19 | 25 | +6 | Mongol: The Rise of Genghis Khan | $107,000 | $112,212 | +$5,212 | +4.9% | 5 | $307,000 | $312,051 | 2 | Picturehouse | - |
| 20 | 29 | +9 | The Children of Huang Shi | $98,500 | $91,255 | -$7,245 | -7.4% | 43 | $328,000 | $320,707 | 4 | Sony Pictures Classics | - |
| 21 | 32 | +11 | When Did You Last See Your Father? | $89,400 | $81,100 | -$8,300 | -9.3% | 21 | $150,000 | $141,591 | 2 | Sony Pictures Classics | - |
| 22 | 30 | +8 | Roman de gare | $86,800 | $85,920 | -$880 | -1% | 38 | $1,115,000 | $1,114,106 | 8 | The Samuel Goldwyn Company | - |
| 23 | 31 | +8 | War, Inc. | $85,000 | $81,172 | -$3,828 | -4.5% | 32 | $236,000 | $232,629 | 4 | First Look International | - |
| 24 | 35 | +11 | The Forbidden Kingdom | $72,000 | $67,988 | -$4,012 | -5.6% | 105 | $52,044,000 | $52,040,293 | 9 | Lionsgate | - |
| 25 | 38 | +13 | Priceless | $49,000 | $45,546 | -$3,454 | -7% | 35 | $1,785,000 | $1,781,512 | 12 | The Samuel Goldwyn Company | - |
| 26 | 43 | +17 | Reprise | $35,200 | $34,552 | -$648 | -1.8% | 15 | $385,000 | $384,722 | 5 | Miramax | - |
| 27 | 50 | +23 | Superhero Movie | $26,000 | $26,063 | +$63 | +0.2% | 59 | $25,778,000 | $25,777,962 | 12 | Metro-Goldwyn-Mayer (MGM) | - |
| 28 | 56 | +28 | Under the Same Moon | $24,000 | $18,601 | -$5,399 | -22.5% | 47 | $12,552,000 | $12,546,352 | 13 | The Weinstein Company | - |
| 29 | 52 | +23 | The Foot Fist Way | $21,700 | $24,507 | +$2,807 | +12.9% | 25 | $145,000 | $148,132 | 3 | Paramount Vantage | - |
| 30 | 57 | +27 | Fugitive Pieces | $18,200 | $18,193 | -$7 | <0.1% | 19 | $502,000 | $502,478 | 7 | The Samuel Goldwyn Company | - |
| 31 | 58 | +27 | Encounters at the End of the World | $17,500 | $17,730 | +$230 | +1.3% | 1 | $25,700 | $25,913 | 1 | THINKFilm | - |
| 32 | 66 | +34 | My Blueberry Nights | $10,500 | $10,222 | -$278 | -2.6% | 15 | $821,000 | $820,751 | 11 | The Weinstein Company | - |
| 33 | 71 | +38 | Baghead | $8,900 | $8,640 | -$260 | -2.9% | 2 | $8,900 | $8,640 | 1 | Sony Pictures Classics | - |
| 34 | 89 | +55 | The Year My Parents Went on Vacation | $4,300 | $4,094 | -$206 | -4.8% | 4 | $774,000 | $773,635 | 18 | City Lights Pictures | - |
