| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Sex and the City | $78,251 | -47.2% | 16 | +1 | $4,890 | $279,629 | 2 | Alexandra Films | false | false |
| 2 | 2 | Indiana Jones and the Kingdom of the Crystal Skull | $57,194 | -18.6% | 19 | - | $3,010 | $587,333 | 4 | Prooptiki | false | false |
| 3 | - | The Happening | $32,955 | - | 7 | - | $4,707 | $32,955 | 1 | Alexandra Films | true | false |
| 4 | - | The Incredible Hulk | $32,758 | - | 9 | - | $3,639 | $32,758 | 1 | Prooptiki | true | false |
| 5 | - | My Blueberry Nights | $11,120 | - | 4 | - | $2,780 | $11,120 | 1 | Sunny Films | true | false |
| 6 | 3 | What Happens in Vegas | $9,123 | -34.3% | 7 | - | $1,303 | $162,542 | 5 | Alexandra Films | false | false |
| 7 | 4 | 88 Minutes | $7,565 | -41.4% | 5 | - | $1,513 | $65,440 | 3 | Alexandra Films | false | false |
| 8 | 5 | Horton Hears a Who! | $5,586 | -21.4% | 9 | - | $620 | $169,790 | 8 | Alexandra Films | false | false |
| 9 | 6 | Love in the Time of Cholera | $2,524 | -42.5% | 4 | - | $631 | $21,334 | 3 | Prooptiki | false | false |
| 10 | 10 | Speed Racer | $1,056 | -44% | 6 | - | $176 | $16,804 | 5 | Alexandra Films | false | false |
| 11 | 9 | Fool's Gold | $666 | -66.8% | 3 | -1 | $222 | $135,061 | 7 | Alexandra Films | false | false |
| 12 | 8 | Iron Man | $628 | -77.8% | 2 | -7 | $314 | $150,207 | 7 | Prooptiki | false | false |
| 13 | 12 | 99 Francs | $609 | -27.8% | 3 | - | $203 | $11,743 | 6 | Big Bang Media | false | false |
| 14 | 7 | 21 | $591 | -83.5% | 7 | -2 | $84 | $123,131 | 6 | Alexandra Films | false | false |
| 15 | - | In the Valley of Elah | $318 | - | 4 | - | $79 | $7,095 | 9 | Prooptiki | false | false |
| 16 | 14 | Forgetting Sarah Marshall | $308 | -20.4% | 4 | - | $77 | $42,521 | 8 | Prooptiki | false | false |
| 17 | 15 | The Spiderwick Chronicles | $292 | -0.3% | 2 | +1 | $146 | $72,243 | 11 | Prooptiki | false | false |
| 18 | 18 | The Bucket List | $289 | +120.6% | 5 | +2 | $57 | $100,848 | 10 | Alexandra Films | false | false |
| 19 | 13 | The Eye | $133 | -69.1% | 3 | -2 | $44 | $39,662 | 8 | Alexandra Films | false | false |
| 20 | 11 | Surviving with Wolves | $101 | -89.5% | 4 | - | $25 | $5,574 | 3 | Sunny Films | false | false |
| 21 | 19 | The Mist | $81 | -36.2% | 1 | -2 | $81 | $26,838 | 11 | Sunny Films | false | false |
| 22 | - | Mad Money | $43 | - | 1 | - | $43 | $34,608 | 9 | Sunny Films | false | false |
| 23 | - | 3:10 to Yuma | $39 | - | 2 | - | $19 | $28,488 | 16 | - | false | false |
| 24 | 21 | The Game Plan | $39 | -2.5% | 1 | -1 | $39 | $81,927 | 13 | Sunny Films | false | false |
| 25 | - | You, the Living | $14 | - | 1 | - | $14 | $1,135 | 9 | Big Bang Media | false | false |
