| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Indiana Jones and the Kingdom of the Crystal Skull | $347,251 | -29.6% | 70 | +1 | $4,960 | $2,034,630 | 3 | N/A | false | false |
| 2 | 2 | What Happens in Vegas | $253,363 | -17.9% | 48 | -2 | $5,278 | $1,823,117 | 4 | N/A | false | false |
| 3 | - | Made of Honor | $210,808 | - | 31 | - | $6,800 | $218,091 | 1 | N/A | true | false |
| 4 | 3 | Speed Racer | $170,703 | -37.1% | 66 | -9 | $2,586 | $2,576,235 | 5 | N/A | false | false |
| 5 | - | Drillbit Taylor | $161,656 | - | 31 | - | $5,214 | $161,656 | 1 | N/A | true | false |
| 6 | 4 | Street Kings | $85,979 | -10.6% | 25 | - | $3,439 | $251,424 | 2 | N/A | false | false |
| 7 | - | Whisper | $85,530 | - | 19 | - | $4,501 | $93,428 | 1 | N/A | true | false |
| 8 | 5 | Definitely, Maybe | $37,408 | -42.5% | 17 | -4 | $2,200 | $146,479 | 2 | N/A | false | false |
| 9 | 7 | The Last Time | $34,298 | -35% | 16 | +1 | $2,143 | $124,700 | 2 | N/A | false | false |
| 10 | 6 | Shattered | $34,194 | -41.6% | 18 | -1 | $1,899 | $139,861 | 2 | N/A | false | false |
| 11 | - | My Blueberry Nights | $21,627 | - | 5 | - | $4,325 | $24,107 | 1 | N/A | true | false |
| 12 | 8 | Iron Man | $18,677 | -61.1% | 26 | -21 | $718 | $1,879,144 | 6 | N/A | false | false |
| 13 | 9 | P2 | $11,035 | -65.8% | 14 | -5 | $788 | $296,362 | 5 | N/A | false | false |
| 14 | 10 | Rendition | $10,790 | -65.2% | 10 | -6 | $1,079 | $230,618 | 4 | N/A | false | false |
| 15 | 14 | Bridge to Terabithia | $9,524 | -24% | 13 | -1 | $732 | $328,530 | 9 | N/A | false | false |
| 16 | 11 | 21 | $9,337 | -55.4% | 9 | -4 | $1,037 | $782,564 | 7 | N/A | false | false |
| 17 | 12 | Shutter | $7,902 | -59.1% | 6 | -5 | $1,317 | $491,356 | 6 | N/A | false | false |
| 18 | 13 | Halloween | $6,512 | -64.6% | 12 | +1 | $542 | $162,120 | 4 | N/A | false | false |
| 19 | 16 | 4 Months, 3 Weeks and 2 Days | $5,093 | +38.1% | 2 | - | $2,546 | $22,777 | 2 | N/A | false | false |
| 20 | 25 | La Vie En Rose | $4,364 | +310.2% | 1 | -2 | $4,364 | $131,079 | 8 | N/A | false | false |
| 21 | 18 | Employee of the Month | $4,263 | +29.2% | 4 | -2 | $1,065 | $235,356 | 6 | N/A | false | false |
| 22 | 15 | KM 31: Kilometre 31 | $2,805 | -32% | 1 | -1 | $2,805 | $239,593 | 8 | N/A | false | false |
| 23 | 20 | Crank | $1,843 | -8.8% | 2 | -1 | $921 | $101,375 | 7 | N/A | false | false |
| 24 | 24 | Lassie | $698 | -43% | 3 | - | $232 | $83,143 | 6 | N/A | false | false |
| 25 | 19 | Untraceable | $401 | -84.1% | 2 | -1 | $200 | $414,784 | 8 | N/A | false | false |
