| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Sex and the City | $6,075,681 | -65% | 469 | +9 | $12,954 | $31,631,284 | 2 | Entertainment Film Distributors | false | false |
| 2 | 2 | Indiana Jones and the Kingdom of the Crystal Skull | $5,261,688 | -52% | 535 | -5 | $9,834 | $64,404,090 | 3 | Paramount Pictures International | false | false |
| 3 | - | Superhero Movie | $1,676,552 | - | 396 | - | $4,233 | $1,676,552 | 1 | Momentum Pictures | true | false |
| 4 | - | Prom Night | $1,000,364 | - | 285 | - | $3,510 | $1,000,364 | 1 | Sony Pictures Releasing | true | false |
| 5 | - | Gone Baby Gone | $691,467 | - | 259 | - | $2,669 | $691,467 | 1 | Walt Disney Pictures | true | false |
| 6 | 3 | What Happens in Vegas | $571,932 | -55% | 275 | -118 | $2,079 | $14,591,061 | 5 | 20th Century Fox International | false | false |
| 7 | 4 | Iron Man | $561,459 | -55% | 341 | -82 | $1,646 | $32,970,372 | 6 | Paramount Pictures International | false | false |
| 8 | - | Sarkar Raj | $369,707 | - | 49 | - | $7,545 | $369,707 | 1 | Eros Worldwide | true | false |
| 9 | - | Mongol: The Rise of Genghis Khan | $365,033 | - | 76 | - | $4,803 | $365,033 | 1 | The Works UK Distribution | true | false |
| 10 | 6 | Harold & Kumar Escape from Guantanamo Bay | $219,153 | -58.3% | 181 | +4 | $1,210 | $1,090,035 | 2 | Entertainment Film Distributors | false | false |
| 11 | 5 | Nim's Island | $196,018 | -64.7% | 344 | -21 | $569 | $7,106,404 | 6 | Universal Pictures International (UPI) | false | false |
| 12 | 8 | Speed Racer | $109,695 | -49.3% | 162 | -125 | $677 | $3,181,950 | 5 | Warner Bros. | false | false |
| 13 | 7 | Forgetting Sarah Marshall | $55,156 | -76.4% | 58 | -132 | $950 | $14,878,755 | 7 | Universal Pictures International (UPI) | false | false |
| 14 | 10 | Caramel | $31,093 | -58.9% | 21 | -13 | $1,480 | $788,196 | 4 | Momentum Pictures | false | false |
| 15 | - | Let's Get Lost | $30,490 | - | 10 | - | $3,049 | $30,490 | 1 | - | true | false |
| 16 | 15 | Persepolis | $29,143 | -39.7% | 18 | -5 | $1,619 | $1,602,074 | 7 | Optimum Releasing | false | false |
| 17 | 13 | In Bruges | $19,852 | -65.6% | 15 | -23 | $1,323 | $9,659,983 | 14 | Universal Pictures International (UPI) | false | false |
| 18 | 14 | Jules and Jim 2008 Re-release | $17,290 | -65.9% | 5 | -8 | $3,458 | $108,935 | 2 | British Film Institute (BFI) | false | false |
| 19 | 27 | Underdog | $15,991 | +37.2% | 39 | - | $410 | $2,858,840 | 19 | Walt Disney Pictures | false | false |
| 20 | 12 | Made of Honor | $15,449 | -77.1% | 20 | -57 | $772 | $4,659,330 | 6 | Sony Pictures Releasing | false | false |
| 21 | 18 | Happy-Go-Lucky | $15,321 | -39.9% | 17 | -7 | $901 | $3,055,614 | 8 | Momentum Pictures | false | false |
| 22 | 17 | Step Up 2: The Streets | $10,502 | -60.1% | 29 | -56 | $362 | $20,955,124 | 12 | Universal Pictures International (UPI) | false | false |
| 23 | 22 | California Dreamin' | $9,458 | -50.2% | 5 | -1 | $1,891 | $40,951 | 2 | Artificial Eye | false | false |
| 24 | 16 | Doomsday | $7,922 | -75.8% | 6 | -41 | $1,320 | $2,061,794 | 5 | Universal Pictures International (UPI) | false | false |
| 25 | 28 | The Spiderwick Chronicles | $7,785 | -33% | 32 | -23 | $243 | $20,855,961 | 12 | Paramount Pictures International | false | false |
| 26 | 29 | The Diving Bell and the Butterfly | $7,326 | -32% | 11 | -1 | $666 | $1,748,458 | 18 | Pathé | false | false |
| 27 | 24 | Heartbeat Detector | $7,020 | -56.8% | 3 | - | $2,340 | $125,699 | 4 | Trinity Filmed Entertainment | false | false |
| 28 | 26 | Smart People | $5,628 | -56.5% | 8 | -6 | $703 | $385,486 | 4 | Icon Film Distribution | false | false |
| 29 | 51 | The Game Plan | $5,118 | +117% | 21 | -2 | $243 | $8,357,184 | 14 | Walt Disney Pictures | false | false |
| 30 | 20 | Jannat: In Search of Heaven... | $5,030 | -78.6% | 10 | -4 | $503 | $302,341 | 4 | - | false | false |
| 31 | 49 | Joy Division | $3,830 | +25.4% | 6 | +3 | $638 | $182,842 | 6 | N/A | false | false |
| 32 | 9 | Welcome Home, Roscoe Jenkins | $3,698 | -95.4% | 8 | -92 | $462 | $122,050 | 2 | Universal Pictures International (UPI) | false | false |
| 33 | 38 | Honeydripper | $3,633 | -25.8% | 6 | -1 | $605 | $147,706 | 5 | Axiom Films | false | false |
| 34 | 40 | XXY | $3,436 | -27.1% | 4 | +1 | $859 | $107,525 | 5 | Peccadillo Pictures | false | false |
| 35 | 32 | Lars and the Real Girl | $3,119 | -62.3% | 4 | -6 | $779 | $861,314 | 12 | Verve Pictures | false | false |
| 36 | 42 | The Bank Job | $3,108 | -31.4% | 1 | - | $3,108 | $8,039,218 | 15 | Lionsgate Films | false | false |
| 37 | 37 | Welcome to the Sticks | $2,928 | -49.4% | 3 | -2 | $976 | $198,470 | 10 | Pathé | false | false |
| 38 | 50 | My Brother is an Only Child | $2,527 | -1.3% | 6 | +3 | $421 | $637,720 | 10 | Revolver Entertainment | false | false |
| 39 | - | Private Property | $2,521 | - | 3 | - | $840 | $48,403 | 8 | Soda Pictures | false | false |
| 40 | 52 | The Ugly Duckling and Me! | $2,334 | +10.8% | 10 | +3 | $233 | $826,583 | 49 | Eclipse Pictures | false | false |
| 41 | 21 | Cassandra's Dream | $2,070 | -90.6% | 2 | -21 | $1,035 | $215,065 | 3 | Optimum Releasing | false | false |
| 42 | 56 | The Last Mistress | $2,064 | +29.1% | 4 | +1 | $516 | $78,608 | 9 | Artificial Eye | false | false |
| 43 | 48 | Where in the World Is Osama Bin Laden? | $1,993 | -35.1% | 4 | -1 | $498 | $136,414 | 5 | Optimum Releasing | false | false |
| 44 | 19 | Woodstock Villa | $1,977 | -91.9% | 5 | -8 | $395 | $38,830 | 2 | DM Productions | false | false |
| 45 | 45 | Flashbacks of a Fool | $1,865 | -46.9% | 3 | -2 | $621 | $900,575 | 8 | Walt Disney Pictures | false | false |
| 46 | 41 | The Orphanage | $1,764 | -61.7% | 1 | -4 | $1,764 | $3,449,892 | 12 | Optimum Releasing | false | false |
| 47 | 67 | You, the Living | $1,707 | +386.3% | 1 | - | $1,707 | $193,239 | 11 | Artificial Eye | false | false |
| 48 | 58 | Garbage Warrior | $1,408 | +0.5% | 1 | - | $1,408 | $8,844 | 3 | ICA Films | false | false |
| 49 | 73 | Funny Games | $1,400 | +2,053.8% | 3 | +2 | $466 | $405,969 | 10 | Tartan | false | false |
| 50 | - | The Edge of Heaven | $1,331 | - | 2 | - | $665 | $279,263 | 16 | Artificial Eye | false | false |
| 51 | 44 | Charlie Bartlett | $1,050 | -71.2% | 2 | -11 | $525 | $384,705 | 4 | Verve Pictures | false | false |
| 52 | 35 | Son of Rambow | $979 | -84.6% | 2 | -10 | $489 | $8,219,888 | 10 | Optimum Releasing | false | false |
| 53 | 34 | The Eye | $673 | -90.7% | 2 | -10 | $336 | $3,648,328 | 7 | Lionsgate Films | false | false |
| 54 | 36 | Shotgun Stories | $577 | -90.4% | 2 | -5 | $288 | $28,698 | 3 | Vertigo Films | false | false |
| 55 | 74 | Manufactured Landscapes | $191 | +377.5% | 1 | - | $191 | $37,605 | 5 | British Film Institute (BFI) | false | false |
| 56 | 62 | Love in the Time of Cholera | $169 | -68.2% | 1 | - | $169 | $736,516 | 12 | Momentum Pictures | false | false |
| 57 | 68 | Vexille | $163 | -44% | 1 | - | $163 | $6,412 | 5 | Momentum Pictures | false | false |
| 58 | - | In Memory of My Father | $156 | - | 1 | - | $156 | $156 | 1 | Scanbox Entertainment | true | false |
| 59 | - | The Aerial | $91 | - | 1 | - | $91 | $7,481 | - | Periscoop Film | - | false |
| 60 | 53 | Terror's Advocate | $77 | -95.9% | 1 | -2 | $77 | $35,504 | 4 | Artificial Eye | false | false |
| 61 | 61 | Still Life | $39 | -93.9% | 1 | -1 | $39 | $75,967 | 19 | British Film Institute (BFI) | false | false |
| 62 | 54 | 4 Months, 3 Weeks and 2 Days | $39 | -97.9% | 1 | -1 | $39 | $589,837 | 23 | Artificial Eye | false | false |
| 63 | 65 | Grindhouse | $39 | -92% | 1 | - | $39 | $189,837 | 11 | Momentum Pictures | false | false |
