| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Sex and the City | $17,374,683 | - | 460 | - | $37,771 | $17,374,683 | 1 | Entertainment Film Distributors | true | false |
| 2 | 1 | Indiana Jones and the Kingdom of the Crystal Skull | $10,964,189 | -54.6% | 540 | +2 | $20,304 | $54,673,902 | 2 | Paramount Pictures International | false | false |
| 3 | 2 | What Happens in Vegas | $1,270,379 | -30.2% | 393 | -12 | $3,232 | $13,327,362 | 4 | 20th Century Fox International | false | false |
| 4 | 3 | Iron Man | $1,246,992 | -24.4% | 423 | -51 | $2,947 | $31,968,064 | 5 | Paramount Pictures International | false | false |
| 5 | 5 | Nim's Island | $555,212 | -4.4% | 365 | -25 | $1,521 | $6,819,608 | 5 | Universal Pictures International (UPI) | false | false |
| 6 | - | Harold & Kumar Escape from Guantanamo Bay | $525,854 | - | 177 | - | $2,970 | $525,854 | 1 | Entertainment Film Distributors | true | false |
| 7 | 4 | Forgetting Sarah Marshall | $233,946 | -63.4% | 190 | -160 | $1,231 | $14,729,013 | 6 | Universal Pictures International (UPI) | false | false |
| 8 | 6 | Speed Racer | $216,542 | -32.5% | 287 | -113 | $754 | $3,045,452 | 4 | Warner Bros. | false | false |
| 9 | - | Welcome Home, Roscoe Jenkins | $80,024 | - | 100 | - | $800 | $80,024 | 1 | Universal Pictures International (UPI) | true | false |
| 10 | 9 | Caramel | $75,565 | -45.8% | 34 | -15 | $2,222 | $703,983 | 3 | Momentum Pictures | false | false |
| 11 | 22 | Horton Hears a Who! | $70,878 | +116.3% | 142 | +27 | $499 | $16,989,306 | 11 | 20th Century Fox International | false | false |
| 12 | 7 | Made of Honor | $67,586 | -71.6% | 77 | -137 | $877 | $4,619,447 | 5 | Sony Pictures Releasing | false | false |
| 13 | 10 | In Bruges | $57,747 | -51.4% | 38 | -46 | $1,519 | $9,373,141 | 13 | Universal Pictures International (UPI) | false | false |
| 14 | - | Jules and Jim 2008 Re-release | $50,711 | - | 13 | - | $3,900 | $50,711 | 1 | British Film Institute (BFI) | true | false |
| 15 | 12 | Persepolis | $48,315 | -39.9% | 23 | -11 | $2,100 | $1,543,468 | 6 | Optimum Releasing | false | false |
| 16 | 8 | Doomsday | $32,683 | -79.2% | 47 | -161 | $695 | $2,020,587 | 4 | Universal Pictures International (UPI) | false | false |
| 17 | 25 | Step Up 2: The Streets | $26,318 | +58.6% | 85 | +32 | $309 | $20,820,240 | 11 | Universal Pictures International (UPI) | false | false |
| 18 | 17 | Happy-Go-Lucky | $25,499 | -54.2% | 24 | -18 | $1,062 | $3,029,503 | 7 | Momentum Pictures | false | false |
| 19 | - | Woodstock Villa | $24,485 | - | 13 | - | $1,883 | $24,485 | 1 | DM Productions | true | false |
| 20 | 15 | Jannat: In Search of Heaven... | $23,454 | -60.3% | 14 | -6 | $1,675 | $284,522 | 3 | - | false | false |
| 21 | 11 | Cassandra's Dream | $22,101 | -76.4% | 23 | -27 | $960 | $191,429 | 2 | Optimum Releasing | false | false |
| 22 | - | California Dreamin' | $19,009 | - | 6 | - | $3,168 | $19,009 | 1 | Artificial Eye | true | false |
| 23 | 20 | Bhoothnath | $16,724 | -56.7% | 18 | -9 | $929 | $404,071 | 4 | Eros Worldwide | false | false |
| 24 | 24 | Heartbeat Detector | $16,268 | -30.8% | 3 | -3 | $5,422 | $110,824 | 3 | Trinity Filmed Entertainment | false | false |
| 25 | 13 | Shutter | $16,100 | -75.8% | 22 | -39 | $731 | $356,276 | 3 | 20th Century Fox International | false | false |
| 26 | 16 | Smart People | $12,933 | -78% | 14 | -35 | $923 | $368,500 | 3 | Icon Film Distribution | false | false |
| 27 | 26 | Underdog | $11,659 | -27% | 39 | -3 | $298 | $2,851,637 | 18 | Walt Disney Pictures | false | false |
| 28 | 14 | The Spiderwick Chronicles | $11,619 | -80.5% | 55 | -153 | $211 | $20,975,624 | 11 | Paramount Pictures International | false | false |
| 29 | 30 | The Diving Bell and the Butterfly | $10,775 | -13% | 12 | - | $897 | $1,737,592 | 17 | Pathé | false | false |
| 30 | - | Chemical Wedding | $9,439 | - | 18 | - | $524 | $9,439 | 1 | - | true | false |
| 31 | 18 | 21 | $9,005 | -80.6% | 13 | -47 | $692 | $10,913,306 | 8 | Sony Pictures Releasing | false | false |
| 32 | 52 | Lars and the Real Girl | $8,282 | +246.7% | 10 | +3 | $828 | $851,468 | 11 | Verve Pictures | false | false |
| 33 | 35 | A Secret | $7,749 | +9.9% | 3 | +1 | $2,583 | $68,262 | 4 | Arrow Films | false | false |
| 34 | 19 | The Eye | $7,200 | -83% | 12 | -44 | $600 | $3,664,734 | 6 | Lionsgate Films | false | false |
| 35 | 43 | Son of Rambow | $6,340 | +42.8% | 12 | -7 | $528 | $8,268,807 | 9 | Optimum Releasing | false | false |
| 36 | 33 | Shotgun Stories | $6,029 | -29.3% | 7 | - | $861 | $22,711 | 2 | Vertigo Films | false | false |
| 37 | 31 | Welcome to the Sticks | $5,781 | -47.9% | 5 | -40 | $1,156 | $190,991 | 9 | Pathé | false | false |
| 38 | 27 | Honeydripper | $4,897 | -64.8% | 7 | -5 | $699 | $139,035 | 4 | Axiom Films | false | false |
| 39 | 42 | Street Kings | $4,784 | +1.2% | 5 | +1 | $956 | $2,732,856 | 7 | 20th Century Fox International | false | false |
| 40 | 28 | XXY | $4,715 | -65.7% | 3 | -3 | $1,571 | $100,779 | 4 | Peccadillo Pictures | false | false |
| 41 | 36 | The Orphanage | $4,604 | -28.8% | 5 | -1 | $920 | $3,460,551 | 11 | Optimum Releasing | false | false |
| 42 | 46 | The Bank Job | $4,530 | +33.1% | 1 | - | $4,530 | $8,079,843 | 14 | Lionsgate Films | false | false |
| 43 | 23 | Timber Falls | $3,827 | -84.2% | 9 | -13 | $425 | $53,335 | 2 | Scanbox Entertainment | false | false |
| 44 | 21 | Charlie Bartlett | $3,641 | -90.1% | 13 | -70 | $280 | $380,063 | 3 | Verve Pictures | false | false |
| 45 | 48 | Flashbacks of a Fool | $3,514 | +19.2% | 5 | -1 | $702 | $901,177 | 7 | Walt Disney Pictures | false | false |
| 46 | 47 | Shine a Light | $3,415 | +9.3% | 2 | -2 | $1,707 | $1,298,631 | 8 | 20th Century Fox International | false | false |
| 47 | - | The Unwinking Gaze: The Inside Story of the Dalai Lama's Struggle for Tibet | $3,155 | - | 5 | - | $631 | $3,155 | 1 | MercuryMedia International | true | false |
| 48 | 59 | Where in the World Is Osama Bin Laden? | $3,072 | +382.3% | 5 | +2 | $614 | $132,059 | 4 | Optimum Releasing | false | false |
| 49 | 41 | Joy Division | $3,055 | -41.5% | 3 | -2 | $1,018 | $172,627 | 5 | N/A | false | false |
| 50 | 45 | My Brother is an Only Child | $2,560 | -33.6% | 3 | -1 | $853 | $636,108 | 9 | Revolver Entertainment | false | false |
| 51 | 38 | The Game Plan | $2,358 | -60.7% | 23 | -9 | $102 | $8,403,024 | 13 | Walt Disney Pictures | false | false |
| 52 | 55 | The Ugly Duckling and Me! | $2,107 | +12.2% | 7 | -2 | $301 | $829,477 | 48 | Eclipse Pictures | false | false |
| 53 | 34 | Terror's Advocate | $1,889 | -75% | 3 | - | $629 | $31,328 | 3 | Artificial Eye | false | false |
| 54 | - | 4 Months, 3 Weeks and 2 Days | $1,881 | - | 2 | - | $940 | $592,172 | 22 | Artificial Eye | false | false |
| 55 | 50 | Tashan | $1,613 | -44.2% | 2 | -2 | $806 | $702,087 | 6 | Yash Raj Films | false | false |
| 56 | 61 | The Last Mistress | $1,599 | +185.5% | 3 | +2 | $533 | $75,353 | 8 | Artificial Eye | false | false |
| 57 | - | I'm a Cyborg, But That's OK | $1,494 | - | 1 | - | $1,494 | $23,432 | 9 | Tartan | false | false |
| 58 | 51 | Garbage Warrior | $1,401 | -42.2% | 1 | -1 | $1,401 | $5,527 | 2 | ICA Films | false | false |
| 59 | 32 | The Oxford Murders | $1,027 | -89.8% | 3 | -5 | $342 | $453,890 | 6 | - | false | false |
| 60 | 66 | The Conformist 2008 Re-release | $757 | +160.1% | 2 | +1 | $378 | $219,923 | 14 | British Film Institute (BFI) | false | false |
| 61 | 72 | Still Life | $642 | +1,505% | 2 | +1 | $321 | $75,890 | 18 | British Film Institute (BFI) | false | false |
| 62 | 56 | Love in the Time of Cholera | $531 | -71.7% | 1 | -2 | $531 | $726,169 | 11 | Momentum Pictures | false | false |
| 63 | 37 | Fool's Gold | $513 | -91.7% | 2 | -13 | $256 | $4,753,969 | 7 | Warner Bros. | false | false |
| 64 | 64 | Redacted | $491 | +22.8% | 1 | - | $491 | $40,329 | 12 | Optimum Releasing | false | false |
| 65 | 57 | Grindhouse | $488 | -48.3% | 1 | -2 | $488 | $187,317 | 10 | Momentum Pictures | false | false |
| 66 | 67 | The Air I Breathe | $361 | +90% | 1 | - | $361 | $6,673 | 3 | Pathé | false | false |
| 67 | 71 | You, the Living | $351 | +777.5% | 1 | - | $351 | $191,060 | 10 | Artificial Eye | false | false |
| 68 | 65 | Vexille | $291 | -14.4% | 1 | - | $291 | $6,128 | 4 | Momentum Pictures | false | false |
| 69 | 49 | Dangerous Parking | $270 | -90.8% | 2 | -5 | $135 | $7,337 | 2 | Delanic Films | false | false |
| 70 | 29 | Outpost | $153 | -98.8% | 2 | -26 | $76 | $146,104 | 3 | Vertigo Films | false | false |
| 71 | 70 | REC | $99 | -12.4% | 1 | -1 | $99 | $450,650 | 8 | - | false | false |
| 72 | 60 | Azur & Asmar: The Princes' Quest | $87 | -85.7% | 2 | -2 | $43 | $70,131 | 17 | Soda Pictures | false | false |
| 73 | 53 | Funny Games | $65 | -97.1% | 1 | -5 | $65 | $406,476 | 9 | Tartan | false | false |
| 74 | 54 | Manufactured Landscapes | $40 | -98% | 1 | -1 | $40 | $36,447 | 4 | British Film Institute (BFI) | false | false |
| 75 | 58 | Mister Lonely | $40 | -94.2% | 1 | - | $40 | $30,795 | 12 | Tartan | false | false |
| 76 | 68 | RFK Must Die: The Assassination of Bobby Kennedy | $40 | -76.2% | 1 | - | $40 | $2,218 | 3 | Soda Pictures | false | false |
| 77 | 74 | My Blueberry Nights | $40 | - | 1 | - | $40 | $560,880 | 15 | Optimum Releasing | false | false |
