| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Indiana Jones and the Kingdom of the Crystal Skull | $244,777 | -48.2% | 59 | - | $4,148 | $884,453 | 2 | N/A | false | false |
| 2 | 2 | The Chronicles of Narnia: Prince Caspian | $152,798 | -29.9% | 60 | - | $2,546 | $1,135,311 | 3 | N/A | false | false |
| 3 | - | 21 | $74,395 | - | 20 | - | $3,719 | $74,395 | 1 | N/A | true | false |
| 4 | - | Diary of the Dead | $61,093 | - | 14 | - | $4,363 | $61,093 | 1 | N/A | true | false |
| 5 | 3 | Speed Racer | $51,426 | -42.9% | 64 | - | $803 | $978,959 | 4 | N/A | false | false |
| 6 | - | Street Kings | $42,473 | - | 17 | - | $2,498 | $42,473 | 1 | N/A | true | false |
| 7 | 4 | Iron Man | $20,423 | -55.1% | 46 | - | $443 | $1,314,809 | 5 | N/A | false | false |
| 8 | - | Fragile | $11,200 | - | 14 | - | $800 | $97,522 | 11 | N/A | false | false |
| 9 | 6 | Eastern Promises | $9,459 | -35.5% | 12 | - | $788 | $202,024 | 5 | N/A | false | false |
| 10 | - | Vantage Point | $5,110 | - | 5 | - | $1,022 | $238,382 | 9 | N/A | false | false |
| 11 | 5 | The Ex | $4,305 | -79.4% | 14 | - | $307 | $166,005 | 4 | N/A | false | false |
| 12 | - | Meet the Spartans | $2,902 | - | 20 | - | $145 | $279,495 | 9 | N/A | false | false |
| 13 | 7 | P.S. I Love You | $876 | -83.2% | 23 | - | $38 | $449,283 | 7 | N/A | false | false |
| 14 | 9 | The Marsh | $866 | -59.6% | 21 | - | $41 | $185,516 | 6 | N/A | false | false |
| 15 | - | 30 Days of Night | $841 | - | 1 | - | $841 | $135,297 | 14 | N/A | false | false |
| 16 | 11 | La Vie En Rose | $818 | +25.7% | 5 | - | $163 | $112,480 | 11 | N/A | false | false |
| 17 | - | Gone Baby Gone | $657 | - | 10 | - | $65 | $44,225 | 16 | N/A | false | false |
| 18 | 10 | Shattered | $328 | -84.1% | 13 | - | $25 | $108,370 | 6 | N/A | false | false |
| 19 | - | Horton Hears a Who! | $274 | - | 48 | - | $5 | $605,842 | 12 | N/A | false | false |
| 20 | - | Noah's Ark | $143 | - | 23 | - | $6 | $225,790 | 17 | N/A | false | false |
