| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Indiana Jones and the Kingdom of the Crystal Skull | $197,126 | - | 21 | - | $9,386 | $197,126 | 1 | Prooptiki | true | false |
| 2 | 1 | What Happens in Vegas | $22,558 | -57.1% | 7 | - | $3,222 | $92,873 | 2 | Alexandra Films | false | false |
| 3 | 5 | Horton Hears a Who! | $5,778 | -18.1% | 9 | -2 | $642 | $144,759 | 5 | Alexandra Films | false | false |
| 4 | 2 | 21 | $5,704 | -62.5% | 9 | - | $633 | $111,316 | 3 | Alexandra Films | false | false |
| 5 | 3 | Iron Man | $5,246 | -64.4% | 9 | -2 | $582 | $140,681 | 4 | Prooptiki | false | false |
| 6 | 4 | Fool's Gold | $3,952 | -58.2% | 8 | - | $494 | $128,941 | 4 | Alexandra Films | false | false |
| 7 | 6 | Speed Racer | $2,751 | -42.1% | 4 | - | $687 | $9,560 | 2 | Alexandra Films | false | false |
| 8 | 9 | 99 Francs | $1,247 | -14.7% | 3 | - | $415 | $9,445 | 3 | Big Bang Media | false | false |
| 9 | 7 | Street Kings | $1,162 | -48.4% | 5 | -3 | $232 | $126,679 | 6 | Alexandra Films | false | false |
| 10 | 8 | Forgetting Sarah Marshall | $595 | -65.5% | 2 | -2 | $297 | $41,470 | 5 | Prooptiki | false | false |
| 11 | 11 | The Spiderwick Chronicles | $510 | -48.5% | 3 | -1 | $170 | $72,724 | 8 | Prooptiki | false | false |
| 12 | 10 | The Eye | $274 | -75.9% | 5 | -1 | $54 | $38,897 | 5 | Alexandra Films | false | false |
| 13 | 16 | Mad Money | $220 | +25.7% | 5 | +1 | $44 | $35,108 | 6 | Sunny Films | false | false |
| 14 | 19 | There Will Be Blood | $178 | +334.1% | 4 | +1 | $44 | $24,275 | 9 | Sunny Films | false | false |
| 15 | 15 | The Mist | $174 | -23.7% | 3 | -1 | $58 | $26,009 | 8 | Sunny Films | false | false |
| 16 | 12 | The Bucket List | $141 | -83.9% | 4 | -2 | $35 | $102,802 | 7 | Alexandra Films | false | false |
| 17 | - | In the Valley of Elah | $80 | - | 1 | - | $80 | $6,886 | 6 | Prooptiki | false | false |
| 18 | 20 | The Mosquito Problem and Other Stories | $78 | +143.8% | 2 | - | $39 | $2,760 | 11 | Sunny Films | false | false |
| 19 | 14 | The Game Plan | $77 | -78.5% | 4 | - | $19 | $83,583 | 10 | Sunny Films | false | false |
| 20 | - | The Edge of Heaven | $43 | - | 2 | - | $21 | $15,761 | 9 | Art Fest | false | false |
| 21 | 17 | Definitely, Maybe | $23 | -74.7% | 1 | - | $23 | $18,713 | 7 | Prooptiki | false | false |
| 22 | - | Bee Movie | $14 | - | 1 | - | $14 | $40,065 | 24 | Prooptiki | false | false |
| 23 | 22 | Atonement | $10 | -23.1% | 1 | - | $10 | $49,233 | 21 | Prooptiki | false | false |
| 24 | 18 | No Country for Old Men | $10 | -88.5% | 1 | -2 | $10 | $80,596 | 14 | Prooptiki | false | false |
| 25 | 23 | Cars | $6 | +20% | 1 | - | $6 | $90,713 | 95 | Sunny Films | false | false |
| 26 | 21 | You, the Living | $6 | -64.7% | 1 | - | $6 | $1,152 | 6 | Big Bang Media | false | false |
