| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | What Happens in Vegas | $243,774 | - | 19 | - | $12,830 | $243,774 | 1 | N/A | true | false |
| 2 | 1 | Iron Man | $191,682 | -41.3% | 21 | -2 | $9,127 | $1,437,230 | 3 | N/A | false | false |
| 3 | - | Nim's Island | $120,871 | - | 18 | - | $6,715 | $120,871 | 1 | N/A | true | false |
| 4 | - | Outlaw | $82,335 | - | 16 | - | $5,145 | $82,335 | 1 | N/A | true | false |
| 5 | - | Taymour W Shafika | $52,380 | - | 8 | - | $6,547 | $52,380 | 1 | N/A | true | false |
| 6 | 2 | Untraceable | $51,359 | -73.5% | 16 | - | $3,209 | $296,071 | 2 | N/A | false | false |
| 7 | - | The Night Listener | $51,159 | - | 16 | - | $3,197 | $51,159 | 1 | N/A | true | false |
| 8 | 4 | Step Up 2: The Streets | $25,233 | -72.5% | 15 | -3 | $1,682 | $388,306 | 3 | N/A | false | false |
| 9 | 3 | Speed Racer | $17,596 | -82.3% | 7 | -12 | $2,513 | $133,596 | 2 | N/A | false | false |
| 10 | 10 | College Road Trip | $14,488 | -47.8% | 3 | -1 | $4,829 | $359,579 | 4 | N/A | false | false |
| 11 | 5 | Made of Honor | $10,271 | -75.4% | 3 | -3 | $3,423 | $205,689 | 3 | N/A | false | false |
| 12 | 9 | 21 | $9,943 | -69% | 2 | -3 | $4,971 | $480,410 | 4 | N/A | false | false |
| 13 | 11 | Morgan Ahmed Morgan | $9,822 | -37.4% | 6 | -2 | $1,637 | $679,669 | 6 | N/A | false | false |
| 14 | - | Chrysalis | $8,815 | - | 8 | - | $1,101 | $8,815 | 1 | N/A | true | false |
| 15 | 7 | The Other Boleyn Girl | $4,537 | -87.9% | 1 | -8 | $4,537 | $57,442 | 2 | N/A | false | false |
| 16 | 8 | Before the Devil Knows You're Dead | $2,889 | -91.4% | 1 | -9 | $2,889 | $47,425 | 2 | N/A | false | false |
| 17 | 14 | Horton Hears a Who! | $2,868 | -22.3% | 1 | - | $2,868 | $433,994 | 9 | N/A | false | false |
| 18 | 15 | The Spiderwick Chronicles | $2,826 | -18.2% | 1 | - | $2,826 | $362,043 | 9 | N/A | false | false |
| 19 | 16 | Mad Money | $984 | -59.8% | 1 | - | $984 | $267,606 | 5 | N/A | false | false |
| 20 | 6 | Stop-Loss | $904 | -97.8% | 1 | -17 | $904 | $55,511 | 2 | N/A | false | false |
| 21 | 18 | Rescue Dawn | $656 | -54.9% | 1 | - | $656 | $133,770 | 4 | N/A | false | false |
