| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | Baby Mama | $18,271,000 | $17,407,110 | -$863,890 | -4.7% | 2,543 | $18,271,000 | $17,407,110 | 1 | Universal Pictures | - |
| 2 | 2 | - | Harold & Kumar Escape from Guantanamo Bay | $14,570,000 | $14,908,404 | +$338,404 | +2.3% | 2,510 | $14,570,000 | $14,908,404 | 1 | Warner Bros. | - |
| 3 | 3 | - | The Forbidden Kingdom | $11,230,000 | $11,212,364 | -$17,636 | -0.2% | 3,151 | $38,255,000 | $38,237,498 | 2 | Lionsgate | - |
| 4 | 4 | - | Forgetting Sarah Marshall | $11,014,000 | $11,028,060 | +$14,060 | +0.1% | 2,799 | $35,077,000 | $35,090,955 | 2 | Universal Pictures | - |
| 5 | 5 | - | Nim's Island | $4,525,000 | $4,548,792 | +$23,792 | +0.5% | 2,977 | $38,954,000 | $38,977,518 | 4 | Twentieth Century Fox | - |
| 6 | 6 | - | Prom Night | $4,400,000 | $4,508,122 | +$108,122 | +2.5% | 2,821 | $38,115,000 | $38,222,732 | 3 | Screen Gems | - |
| 7 | 7 | - | 21 | $4,000,000 | $4,018,064 | +$18,064 | +0.5% | 2,952 | $75,775,000 | $75,792,625 | 5 | Sony Pictures Releasing | - |
| 8 | 8 | - | 88 Minutes | $3,600,000 | $3,593,890 | -$6,110 | -0.2% | 2,168 | $12,632,000 | $12,625,951 | 2 | Sony Pictures Releasing | - |
| 9 | 9 | - | Horton Hears a Who! | $2,410,000 | $2,486,903 | +$76,903 | +3.2% | 2,159 | $147,883,000 | $147,959,806 | 7 | Twentieth Century Fox | - |
| 10 | 10 | - | Deception | $2,225,000 | $2,312,146 | +$87,146 | +3.9% | 2,001 | $2,225,000 | $2,312,146 | 1 | Twentieth Century Fox | - |
| 11 | 11 | - | Street Kings | $2,125,000 | $2,149,063 | +$24,063 | +1.1% | 1,735 | $23,682,000 | $23,705,977 | 3 | Fox Searchlight Pictures | - |
| 12 | 12 | - | Leatherheads | $1,815,000 | $1,827,555 | +$12,555 | +0.7% | 2,255 | $29,276,000 | $29,287,855 | 4 | Universal Pictures | - |
| 13 | 13 | - | Expelled: No Intelligence Allowed | $1,379,000 | - | - | - | 1,041 | $5,282,000 | - | 2 | Rocky Mountain Pictures | - |
| 14 | 14 | - | Smart People | $909,000 | $895,175 | -$13,825 | -1.5% | 1,036 | $8,298,000 | $8,284,401 | 3 | Miramax | - |
| 15 | 15 | - | Superhero Movie | $853,000 | $869,112 | +$16,112 | +1.9% | 1,103 | $24,897,000 | $24,912,802 | 5 | Metro-Goldwyn-Mayer (MGM) | - |
| 16 | 16 | - | The Visitor | $508,000 | $477,711 | -$30,289 | -6% | 76 | $857,000 | $826,290 | 3 | Overture Films | - |
| 17 | 17 | - | Shine a Light | $419,000 | $425,957 | +$6,957 | +1.7% | 218 | $4,400,000 | $4,406,820 | 4 | Paramount Vantage | - |
| 18 | 18 | - | The Ruins | $415,000 | $420,262 | +$5,262 | +1.3% | 722 | $16,669,000 | $16,673,890 | 4 | DreamWorks | - |
| 19 | 20 | +1 | Under the Same Moon | $400,000 | $394,443 | -$5,557 | -1.4% | 453 | $11,784,000 | $11,778,691 | 6 | The Weinstein Company | - |
| 20 | 19 | -1 | Drillbit Taylor | $384,000 | $395,693 | +$11,693 | +3% | 702 | $30,353,000 | $30,364,117 | 6 | Paramount Pictures | - |
| 21 | 21 | - | Meet the Browns | $330,000 | $367,947 | +$37,947 | +11.5% | 435 | $41,671,000 | $41,708,739 | 6 | Lionsgate | - |
| 22 | 25 | +3 | The Counterfeiters | $283,000 | $268,200 | -$14,800 | -5.2% | 170 | $4,147,000 | $4,132,459 | 10 | Sony Pictures Classics | - |
| 23 | 28 | +5 | Young@Heart | $225,000 | $219,785 | -$5,215 | -2.3% | 56 | $530,000 | $525,272 | 3 | Fox Searchlight Pictures | - |
| 24 | 30 | +6 | The Bank Job | $183,000 | $200,601 | +$17,601 | +9.6% | 239 | $29,570,000 | $29,588,080 | 8 | Lionsgate | - |
| 25 | 32 | +7 | Miss Pettigrew Lives for a Day | $141,000 | $142,610 | +$1,610 | +1.1% | 222 | $12,016,000 | $12,018,325 | 8 | Focus Features | - |
| 26 | 37 | +11 | Priceless | $112,000 | $114,662 | +$2,662 | +2.4% | 44 | $1,114,000 | $1,116,790 | 5 | The Samuel Goldwyn Company | - |
| 27 | 36 | +9 | Never Back Down | $104,000 | $115,918 | +$11,918 | +11.5% | 212 | $24,370,000 | $24,382,339 | 7 | Summit Entertainment | - |
| 28 | 42 | +14 | In Bruges | $77,500 | $77,245 | -$255 | -0.3% | 87 | $7,399,000 | $7,399,059 | 12 | Focus Features | - |
| 29 | 45 | +16 | Then She Found Me | $74,400 | $72,594 | -$1,806 | -2.4% | 9 | $74,400 | $72,594 | 1 | THINKFilm | - |
| 30 | 43 | +13 | My Blueberry Nights | $73,500 | $74,316 | +$816 | +1.1% | 60 | $391,000 | $392,226 | 4 | The Weinstein Company | - |
| 31 | 48 | +17 | Stop-Loss | $62,000 | $62,322 | +$322 | +0.5% | 186 | $10,796,000 | $10,796,776 | 5 | Paramount Pictures | - |
| 32 | 55 | +23 | A Plumm Summer | $60,700 | $53,752 | -$6,948 | -11.4% | 58 | $60,700 | $53,752 | 1 | Freestyle Releasing | - |
| 33 | 50 | +17 | Run Fatboy Run | $60,300 | $58,886 | -$1,414 | -2.3% | 98 | $5,868,000 | $5,926,110 | 5 | Picturehouse | - |
| 34 | 49 | +15 | Where in the World Is Osama Bin Laden? | $58,900 | $60,056 | +$1,156 | +2% | 72 | $263,000 | $264,438 | 2 | The Weinstein Company | - |
| 35 | 56 | +21 | Penelope | $47,000 | $53,449 | +$6,449 | +13.7% | 112 | $9,910,000 | $9,916,560 | 9 | Summit Entertainment | - |
| 36 | 63 | +27 | The Year My Parents Went on Vacation | $38,600 | $36,430 | -$2,170 | -5.6% | 27 | $660,000 | $657,454 | 11 | City Lights Pictures | - |
| 37 | 65 | +28 | Deal | $31,000 | $35,281 | +$4,281 | +13.8% | 50 | $31,000 | $35,281 | 1 | Metro-Goldwyn-Mayer (MGM) | - |
| 38 | 70 | +32 | Roman de gare | $25,500 | $25,484 | -$16 | <0.1% | 2 | $25,500 | $225,484 | 1 | The Samuel Goldwyn Company | - |
| 39 | 71 | +32 | The First Saturday in May | $19,300 | $23,157 | +$3,857 | +20% | 17 | $93,100 | $96,939 | 2 | Truly Indie | - |
| 40 | 80 | +40 | Standard Operating Procedure | $14,900 | $14,108 | -$792 | -5.3% | 2 | $14,900 | $14,108 | 1 | Sony Pictures Classics | - |
| 41 | 76 | +35 | Pathology | $14,000 | $16,665 | +$2,665 | +19% | 46 | $95,900 | $98,531 | 2 | Metro-Goldwyn-Mayer (MGM) | - |
| 42 | 84 | +42 | My Brother is an Only Child | $13,300 | $12,865 | -$435 | -3.3% | 11 | $96,000 | $95,578 | 5 | THINKFilm | - |
| 43 | 79 | +36 | Diary of the Dead | $12,300 | $14,151 | +$1,851 | +15% | 30 | $951,000 | $952,620 | 11 | Third Rail Releasing | - |
| 44 | 85 | +41 | The Singing Revolution | $5,600 | $12,842 | +$7,242 | +129.3% | 3 | $121,000 | $127,832 | 21 | Abramorama | - |
| 45 | 119 | +74 | Blindsight | $2,170 | $1,841 | -$329 | -15.2% | 2 | $70,000 | $69,663 | 8 | Abramorama | - |
| 46 | 120 | +74 | Charlie Bartlett | $1,500 | $1,652 | +$152 | +10.1% | 10 | $3,950,000 | $3,950,294 | 10 | Metro-Goldwyn-Mayer (MGM) | - |
| 47 | 121 | +74 | Dog Days of Summer | $1,400 | $1,482 | +$82 | +5.9% | 1 | $5,300 | $5,383 | 2 | Mountain Top Releasing | - |
| 48 | 132 | +84 | Hats Off | $700 | $704 | +$4 | +0.6% | 1 | $25,900 | $25,939 | 5 | Abramorama | - |
