| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Horton Hears a Who! | $362,534 | +60.5% | 90 | - | $4,028 | $988,372 | 2 | 20th Century Fox International | false | false |
| 2 | - | Superhero Movie | $201,052 | - | 42 | - | $4,786 | $201,052 | 1 | Roadshow Films | true | false |
| 3 | 3 | The Spiderwick Chronicles | $181,738 | +54.8% | 65 | +1 | $2,795 | $642,881 | 3 | Paramount Pictures International | false | false |
| 4 | 6 | Nim's Island | $157,498 | +112.8% | 50 | - | $3,149 | $363,880 | 2 | Paramount Pictures International | false | false |
| 5 | 2 | Street Kings | $115,309 | -29% | 35 | - | $3,294 | $339,166 | 2 | 20th Century Fox International | false | false |
| 6 | 5 | St. Trinian's | $95,310 | +2.1% | 57 | - | $1,672 | $280,817 | 2 | Sony Pictures Releasing | false | false |
| 7 | - | The Painted Veil | $83,977 | - | 13 | - | $6,459 | $83,977 | 1 | Paramount Pictures International | true | false |
| 8 | 7 | Lars and the Real Girl | $71,403 | +2.8% | 19 | +4 | $3,758 | $251,991 | 3 | Rialto Distribution | false | false |
| 9 | 4 | Semi-Pro | $66,338 | -37.1% | 42 | -1 | $1,579 | $464,055 | 3 | Roadshow Films | false | false |
| 10 | 10 | College Road Trip | $52,519 | +35.8% | 37 | +1 | $1,419 | $141,681 | 2 | Walt Disney Pictures | false | false |
| 11 | 9 | Definitely, Maybe | $48,143 | -13.2% | 34 | +1 | $1,415 | $478,513 | 4 | Paramount Pictures International | false | false |
| 12 | - | U2 3D | $44,245 | - | 4 | - | $11,061 | $44,245 | 1 | Roadshow Films | true | false |
| 13 | - | Sydney White | $43,091 | - | 44 | - | $979 | $43,091 | 1 | Hoyts Distribution | true | false |
| 14 | 11 | The Bucket List | $37,791 | +6.4% | 41 | +4 | $921 | $1,235,422 | 10 | Warner Bros. | false | false |
| 15 | 8 | How She Move | $35,643 | -39.4% | 28 | -4 | $1,272 | $279,864 | 3 | Paramount Pictures International | false | false |
| 16 | 14 | Step Up 2: The Streets | $24,784 | +40.8% | 24 | +5 | $1,032 | $1,354,649 | 7 | Paramount Pictures International | false | false |
| 17 | 12 | Two Days in Paris | $23,738 | -27.9% | 15 | -5 | $1,582 | $369,870 | 6 | Hopscotch Films | false | false |
| 18 | 13 | Never Back Down | $16,180 | -47.9% | 25 | -13 | $647 | $322,177 | 4 | Roadshow Films | false | false |
| 19 | - | Tashan | $15,777 | - | 3 | - | $5,259 | $15,777 | 1 | MG Distribution | true | false |
| 20 | - | Hannah Montana and Miley Cyrus: Best of Both Worlds Concert | $12,762 | - | 1 | - | $12,762 | $122,423 | 6 | Walt Disney Pictures | false | false |
| 21 | 19 | No Country for Old Men | $12,387 | +38.7% | 12 | -1 | $1,032 | $764,630 | 13 | Paramount Pictures International | false | false |
| 22 | 21 | Death at a Funeral | $11,673 | +58.4% | 19 | -3 | $614 | $2,661,380 | 16 | Hoyts Distribution | false | false |
| 23 | 16 | Gone Baby Gone | $10,810 | -26.9% | 9 | -4 | $1,201 | $199,937 | 5 | Walt Disney Pictures | false | false |
| 24 | 17 | Run Fatboy Run | $9,960 | -9.4% | 32 | +3 | $311 | $624,158 | 7 | Roadshow Films | false | false |
| 25 | - | Music Within | $9,607 | - | 7 | - | $1,372 | $9,607 | 1 | Rialto Distribution | true | false |
| 26 | 23 | There Will Be Blood | $6,968 | +20.6% | 7 | -3 | $995 | $348,592 | 11 | Walt Disney Pictures | false | false |
| 27 | 15 | Love in the Time of Cholera | $6,198 | -60% | 11 | -4 | $563 | $192,763 | 6 | Rialto Distribution | false | false |
| 28 | 20 | Juno | $6,090 | -21.9% | 19 | -5 | $320 | $1,427,598 | 13 | 20th Century Fox International | false | false |
| 29 | 18 | Rambo | $5,997 | -36.3% | 6 | -6 | $999 | $399,158 | 5 | Sony Pictures Releasing | false | false |
| 30 | 25 | 3:10 to Yuma | $4,694 | -3.5% | 16 | -3 | $293 | $338,283 | 6 | Hoyts Distribution | false | false |
| 31 | 26 | Once | $4,223 | -6.7% | 8 | - | $527 | $619,282 | 21 | Hoyts Distribution | false | false |
| 32 | 22 | The Other Boleyn Girl | $4,193 | -34.4% | 11 | -3 | $381 | $471,848 | 8 | Paramount Pictures International | false | false |
| 33 | 27 | 10,000 BC | $3,623 | +38.9% | 22 | +6 | $164 | $1,065,443 | 8 | Warner Bros. | false | false |
| 34 | 24 | The War on Democracy | $2,909 | -45.2% | 5 | - | $581 | $28,633 | 8 | Hopscotch Films | false | false |
| 35 | - | Blindsight | $2,429 | - | 4 | - | $607 | $14,576 | 2 | Rialto Distribution | false | false |
| 36 | 29 | I Served the King of England | $2,313 | +21.4% | 6 | -3 | $385 | $118,221 | 6 | Rialto Distribution | false | false |
| 37 | - | Across the Universe | $2,216 | - | 1 | - | $2,216 | $10,177 | 2 | Sony Pictures Releasing | false | false |
| 38 | 28 | 27 Dresses | $2,100 | -17.3% | 6 | -8 | $350 | $1,077,651 | 11 | 20th Century Fox International | false | false |
| 39 | 35 | Alvin and the Chipmunks | $1,179 | +73.6% | 6 | +2 | $196 | $2,364,483 | 17 | 20th Century Fox International | false | false |
| 40 | 33 | La Vie En Rose | $676 | -8.3% | 1 | -1 | $676 | $810,815 | 30 | Hoyts Distribution | false | false |
| 41 | 30 | Molière | $581 | -35.4% | 3 | -2 | $193 | $58,804 | 9 | Hopscotch Films | false | false |
| 42 | 32 | P.S. I Love You | $541 | -32% | 2 | -1 | $270 | $409,543 | 9 | Hoyts Distribution | false | false |
| 43 | 34 | Rescue Dawn | $408 | -41.7% | 2 | -2 | $204 | $62,267 | 10 | Hopscotch Films | false | false |
| 44 | 37 | Bella | $178 | +249% | 2 | +1 | $89 | $89,573 | 23 | Hopscotch Films | false | false |
