| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Forgetting Sarah Marshall | $4,256,577 | - | 393 | - | $10,830 | $4,256,577 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | - | The Eye | $1,398,958 | - | 370 | - | $3,780 | $1,398,958 | 1 | Lionsgate Films | true | false |
| 3 | 1 | 21 | $1,087,681 | -46.1% | 348 | -8 | $3,125 | $8,907,457 | 3 | Sony Pictures Releasing | false | false |
| 4 | 2 | Fool's Gold | $945,491 | -51.5% | 398 | - | $2,375 | $3,663,643 | 2 | Warner Bros. | false | false |
| 5 | 3 | In Bruges | $810,222 | -36.5% | 259 | -11 | $3,128 | $7,056,182 | 8 | Universal Pictures International (UPI) | false | false |
| 6 | 5 | Son of Rambow | $552,966 | -52.5% | 305 | -6 | $1,813 | $7,672,760 | 4 | Optimum Releasing | false | false |
| 7 | - | Deception | $508,156 | - | 291 | - | $1,746 | $508,156 | 1 | Entertainment Film Distributors | true | false |
| 8 | 4 | Street Kings | $497,586 | -59.8% | 311 | -42 | $1,599 | $2,261,076 | 2 | 20th Century Fox International | false | false |
| 9 | 6 | The Spiderwick Chronicles | $473,222 | -57.1% | 435 | -36 | $1,087 | $20,370,683 | 6 | Paramount Pictures International | false | false |
| 10 | 9 | Happy-Go-Lucky | $472,700 | -37.9% | 114 | +37 | $4,146 | $1,609,599 | 2 | Momentum Pictures | false | false |
| 11 | 7 | Step Up 2: The Streets | $471,201 | -54.2% | 336 | -39 | $1,402 | $20,250,056 | 6 | Universal Pictures International (UPI) | false | false |
| 12 | - | A Deal Is a Deal | $376,125 | - | 380 | - | $989 | $376,125 | 1 | Worldwide Bonus Entertainment | true | false |
| 13 | - | Tashan | $361,451 | - | 46 | - | $7,857 | $361,451 | 1 | Yash Raj Films | true | false |
| 14 | - | Persepolis | $315,400 | - | 44 | - | $7,168 | $315,400 | 1 | Optimum Releasing | true | false |
| 15 | 10 | Horton Hears a Who! | $263,659 | -61.7% | 366 | -56 | $720 | $16,577,358 | 6 | 20th Century Fox International | false | false |
| 16 | 8 | 27 Dresses | $241,969 | -70.3% | 204 | -162 | $1,186 | $13,146,645 | 5 | 20th Century Fox International | false | false |
| 17 | - | The Oxford Murders | $159,831 | - | 62 | - | $2,577 | $159,831 | 1 | - | true | false |
| 18 | 11 | Flashbacks of a Fool | $77,415 | -84.3% | 140 | -132 | $552 | $809,623 | 2 | Walt Disney Pictures | false | false |
| 19 | 21 | Underdog | $72,972 | -41.2% | 57 | -1 | $1,280 | $2,694,662 | 13 | Walt Disney Pictures | false | false |
| 20 | 19 | The Orphanage | $56,444 | -56.2% | 35 | -33 | $1,612 | $3,329,710 | 6 | Optimum Releasing | false | false |
| 21 | 20 | Shine a Light | $54,928 | -56.4% | 16 | -45 | $3,433 | $1,154,417 | 3 | 20th Century Fox International | false | false |
| 22 | 13 | Never Back Down | $52,523 | -84% | 95 | -149 | $552 | $4,266,794 | 4 | Momentum Pictures | false | false |
| 23 | 22 | The Game Plan | $50,709 | -55.6% | 124 | -42 | $408 | $8,312,978 | 8 | Walt Disney Pictures | false | false |
| 24 | 14 | Pathology | $44,646 | -85% | 60 | -162 | $744 | $1,483,405 | 3 | Entertainment Film Distributors | false | false |
| 25 | 15 | Awake | $41,169 | -83.1% | 62 | -98 | $664 | $3,105,437 | 4 | Icon Film Distribution | false | false |
| 26 | 16 | U Me Aur Hum | $40,520 | -75.7% | 28 | -17 | $1,447 | $785,430 | 3 | Eros Worldwide | false | false |
| 27 | 12 | Leatherheads | $40,338 | -88.6% | 63 | -237 | $640 | $2,029,964 | 3 | Universal Pictures International (UPI) | false | false |
| 28 | 18 | Drillbit Taylor | $35,245 | -74.6% | 69 | -89 | $510 | $4,437,973 | 5 | Paramount Pictures International | false | false |
| 29 | 55 | The Ugly Duckling and Me! | $28,513 | +397.3% | 93 | +77 | $306 | $819,726 | 43 | Eclipse Pictures | false | false |
| 30 | 17 | One Missed Call | $28,283 | -82.8% | 37 | -89 | $764 | $2,339,587 | 4 | Warner Bros. | false | false |
| 31 | 24 | The Water Horse | $27,187 | -62.7% | 77 | -28 | $353 | $9,562,293 | 12 | Sony Pictures Releasing | false | false |
| 32 | 27 | My Brother is an Only Child | $25,305 | -47.4% | 16 | -4 | $1,581 | $560,887 | 4 | Revolver Entertainment | false | false |
| 33 | 28 | Lars and the Real Girl | $19,698 | -50.2% | 13 | -6 | $1,515 | $791,132 | 6 | Verve Pictures | false | false |
| 34 | 30 | There Will Be Blood | $17,006 | -49.3% | 17 | -12 | $1,000 | $9,311,483 | 12 | Walt Disney Pictures | false | false |
| 35 | - | Stop-Loss | $16,282 | - | 24 | - | $678 | $16,282 | 1 | Paramount Pictures International | true | false |
| 36 | 25 | The Other Boleyn Girl | $15,749 | -69.5% | 13 | -26 | $1,211 | $9,222,932 | 8 | Universal Pictures International (UPI) | false | false |
| 37 | 23 | REC | $13,961 | -82% | 18 | -36 | $775 | $437,469 | 3 | - | false | false |
| 38 | 29 | Welcome to the Sticks | $13,853 | -60.4% | 4 | -1 | $3,463 | $128,543 | 4 | Pathé | false | false |
| 39 | 35 | Hannah Montana and Miley Cyrus: Best of Both Worlds Concert | $10,588 | -57.3% | 11 | -11 | $962 | $1,565,388 | 7 | Walt Disney Pictures | false | false |
| 40 | 44 | Love in the Time of Cholera | $10,069 | -19.7% | 13 | -6 | $774 | $686,718 | 6 | Momentum Pictures | false | false |
| 41 | 26 | Krazzy 4 | $9,823 | -79.6% | 12 | -6 | $818 | $268,364 | 3 | Eros Worldwide | false | false |
| 42 | 42 | Grindhouse | $8,747 | -36.6% | 11 | -4 | $795 | $156,736 | 5 | Momentum Pictures | false | false |
| 43 | 43 | Private Property | $8,076 | -36.2% | 2 | - | $4,038 | $26,411 | 2 | Soda Pictures | false | false |
| 44 | 32 | 10,000 BC | $7,767 | -73.1% | 20 | -28 | $388 | $11,417,846 | 7 | Warner Bros. | false | false |
| 45 | 37 | No Country for Old Men | $6,700 | -69% | 7 | -2 | $957 | $14,187,286 | 15 | Paramount Pictures International | false | false |
| 46 | 49 | The Last Mistress | $5,761 | -40.1% | 2 | - | $2,880 | $49,734 | 3 | Artificial Eye | false | false |
| 47 | 39 | The Bank Job | $5,726 | -64.1% | 3 | -12 | $1,908 | $8,050,151 | 9 | Lionsgate Films | false | false |
| 48 | 53 | The 39 Steps 2008 Re-release | $5,688 | -10.3% | 1 | -1 | $5,688 | $38,440 | 3 | Park Circus | false | false |
| 49 | 58 | Be Kind Rewind | $4,741 | +14% | 6 | - | $790 | $7,650,502 | 10 | Pathé | false | false |
| 50 | - | Death Note 2008 Re-release | $4,739 | - | 1 | - | $4,739 | $4,739 | 1 | - | true | false |
| 51 | 36 | Meet the Spartans | $4,578 | -80.1% | 15 | -28 | $305 | $6,390,506 | 6 | 20th Century Fox International | false | false |
| 52 | 47 | Arai Enn 305-il Kadavul | $4,129 | -60.1% | 3 | - | $1,376 | $18,438 | 2 | Ayngaran International | false | false |
| 53 | 38 | The Diving Bell and the Butterfly | $4,116 | -74.5% | 5 | -7 | $823 | $1,639,716 | 12 | Pathé | false | false |
| 54 | 33 | Vantage Point | $3,873 | -85.1% | 7 | -36 | $553 | $11,630,951 | 8 | Sony Pictures Releasing | false | false |
| 55 | 57 | U2 3D | $3,421 | -23.4% | 2 | +1 | $1,710 | $1,372,621 | 10 | Revolver Entertainment | false | false |
| 56 | 79 | My Blueberry Nights | $3,034 | +2,233.8% | 4 | +3 | $758 | $554,862 | 10 | Optimum Releasing | false | false |
| 57 | 52 | Juno | $3,030 | -63.6% | 2 | -4 | $1,515 | $19,319,776 | 12 | 20th Century Fox International | false | false |
| 58 | 54 | Water Lilies | $2,934 | -52.7% | 2 | -5 | $1,467 | $110,973 | 7 | Slingshot Studios | false | false |
| 59 | 34 | Penelope | $2,748 | -89.2% | 16 | -51 | $171 | $6,496,687 | 13 | Momentum Pictures | false | false |
| 60 | 41 | How She Move | $2,507 | -82.3% | 6 | -10 | $417 | $368,723 | 4 | Paramount Pictures International | false | false |
| 61 | 51 | You, the Living | $2,468 | -71.6% | 1 | -4 | $2,468 | $171,481 | 5 | Artificial Eye | false | false |
| 62 | 56 | Sweeney Todd: The Demon Barber of Fleet Street | $1,985 | -57.9% | 2 | -1 | $992 | $21,747,800 | 14 | Warner Bros. | false | false |
| 63 | 67 | The Conformist 2008 Re-release | $1,499 | +78.7% | 3 | +2 | $499 | $207,179 | 9 | British Film Institute (BFI) | false | false |
| 64 | 65 | Flight of the Red Balloon | $1,132 | +14% | 2 | - | $566 | $83,311 | 7 | Park Circus | false | false |
| 65 | 62 | I'm a Cyborg, But That's OK | $1,082 | -40% | 2 | +1 | $541 | $17,054 | 4 | Tartan | false | false |
| 66 | 48 | Botched | $1,003 | -90.3% | 4 | -12 | $250 | $16,835 | 2 | Optimum Releasing | false | false |
| 67 | - | Mister Lonely | $983 | - | 2 | - | $491 | $26,035 | 7 | Tartan | false | false |
| 68 | 71 | Under the Bombs | $810 | +50.3% | 1 | - | $810 | $30,026 | 6 | Artificial Eye | false | false |
| 69 | 63 | Redacted | $653 | -54.7% | 3 | - | $217 | $38,311 | 7 | Optimum Releasing | false | false |
| 70 | 46 | The Golden Compass | $609 | -94.4% | 2 | -62 | $304 | $52,308,193 | 21 | Entertainment Film Distributors | false | false |
| 71 | 75 | Still Life | $524 | +6.7% | 1 | - | $524 | $69,279 | 13 | British Film Institute (BFI) | false | false |
| 72 | 78 | The Accidental Husband | $457 | +87.3% | 1 | - | $457 | $4,994,133 | 9 | Momentum Pictures | false | false |
| 73 | - | Asterix at the Olympic Games | $292 | - | 2 | - | $146 | $42,067 | 13 | Pathé | false | false |
| 74 | 73 | Azur & Asmar: The Princes' Quest | $193 | -61.2% | 2 | +1 | $96 | $67,852 | 12 | Soda Pictures | false | false |
| 75 | 68 | Children of Glory | $145 | -82.1% | 1 | -2 | $145 | $33,951 | 7 | Lionsgate Films | false | false |
| 76 | 70 | Captain Eager and the Mark of Voth | $137 | -79.1% | 1 | - | $137 | $1,056 | 2 | ICA Films | false | false |
| 77 | 77 | In the Valley of Elah | $40 | -87.1% | 1 | - | $40 | $1,746,683 | 14 | Optimum Releasing | false | false |
| 78 | 45 | Funny Games | $40 | -99.7% | 1 | -15 | $40 | $391,038 | 4 | Tartan | false | false |
| 79 | 80 | 4 Months, 3 Weeks and 2 Days | $40 | - | 1 | - | $40 | $588,856 | 17 | Artificial Eye | false | false |
| 80 | 76 | The Edge of Heaven | $40 | -91.8% | 1 | - | $40 | $278,227 | 10 | Artificial Eye | false | false |
| 81 | 66 | Away from Her | $16 | -98.2% | 1 | -1 | $16 | $304,528 | 11 | Metrodome Distribution | false | false |
