| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Step Up 2: The Streets | $2,242,559 | - | 308 | - | $7,281 | $2,242,559 | 1 | Moviemax | true | false |
| 2 | - | Horton Hears a Who! | $1,399,334 | - | 463 | - | $3,022 | $1,399,334 | 1 | 20th Century Fox International | true | false |
| 3 | - | 21 | $1,140,274 | - | 247 | - | $4,616 | $1,140,274 | 1 | Sony Pictures Releasing | true | false |
| 4 | 2 | The Kite Runner | $896,337 | -46.6% | 333 | -37 | $2,691 | $11,152,116 | 4 | Filmauro | false | false |
| 5 | 1 | Nim's Island | $841,726 | -50.7% | 272 | -32 | $3,094 | $3,032,042 | 2 | Moviemax | false | false |
| 6 | 3 | Leatherheads | $782,126 | -36.6% | 213 | -5 | $3,671 | $2,403,122 | 2 | Universal Pictures International (UPI) | false | false |
| 7 | 5 | La seconda volta non si scorda mai | $512,931 | -48% | 136 | -81 | $3,771 | $1,953,807 | 2 | Mikado Film | false | false |
| 8 | 4 | Next | $466,894 | -53.4% | 155 | -118 | $3,012 | $4,098,974 | 3 | Medusa Distribuzione | false | false |
| 9 | - | The Last Deadly Mission | $399,332 | - | 161 | - | $2,480 | $399,332 | 1 | Medusa Distribuzione | true | false |
| 10 | 6 | Tutta la vita davanti | $334,426 | -52% | 104 | -105 | $3,215 | $5,277,367 | 4 | Medusa Distribuzione | false | false |
| 11 | 7 | Juno | $292,989 | -56.5% | 165 | -71 | $1,775 | $2,457,291 | 3 | 20th Century Fox International | false | false |
| 12 | - | L'amore non basta | $190,795 | - | 76 | - | $2,510 | $197,146 | 1 | Mediafilm | true | false |
| 13 | 9 | Non pensarci | $186,207 | -50.9% | 59 | -114 | $3,156 | $1,509,061 | 3 | 01 Distribution | false | false |
| 14 | 11 | The Oxford Murders | $180,836 | -48.9% | 95 | -5 | $1,903 | $675,268 | 2 | Warner Bros. | false | false |
| 15 | - | Introducing the Dwights | $152,636 | - | 69 | - | $2,212 | $152,636 | 1 | Lucky Red | true | false |
| 16 | 8 | Amore, bugie & calcetto | $135,401 | -75.8% | 85 | -184 | $1,592 | $2,132,757 | 3 | Warner Bros. | false | false |
| 17 | 17 | Shine a Light | $132,283 | +48.2% | 47 | +40 | $2,814 | $257,649 | 2 | BIM Distribuzione | false | false |
| 18 | - | 10 Items or Less | $99,270 | - | 35 | - | $2,836 | $99,270 | 1 | DNC Entertainment | true | false |
| 19 | 13 | Ci sta un francese, un inglese e un napoletano | $52,276 | -61.2% | 14 | -50 | $3,734 | $748,168 | 4 | Medusa Distribuzione | false | false |
| 20 | 10 | Shoot 'Em Up | $43,924 | -88% | 71 | -123 | $618 | $548,710 | 2 | Eagle Pictures | false | false |
| 21 | 16 | Good Morning Heartache | $38,904 | -65.7% | 30 | -49 | $1,296 | $205,895 | 2 | Medusa Distribuzione | false | false |
| 22 | 22 | The Zone | $31,391 | -42.7% | 12 | -13 | $2,615 | $188,250 | 3 | Sacher Distribuzione | false | false |
| 23 | 21 | The Band's Visit | $28,217 | -53.7% | 13 | -13 | $2,170 | $778,506 | 5 | Mikado Film | false | false |
| 24 | 19 | Before the Devil Knows You're Dead | $27,055 | -61.4% | 10 | -20 | $2,705 | $4,135,749 | 6 | Medusa Distribuzione | false | false |
| 25 | 14 | The Fox and the Child | $26,025 | -79.8% | 46 | -74 | $565 | $2,224,543 | 5 | Lucky Red | false | false |
| 26 | - | La velocità della luce | $16,973 | - | 3 | - | $5,657 | $16,973 | 1 | Mediaplex | true | false |
| 27 | 20 | Interview | $13,676 | -77.9% | 16 | -28 | $854 | $103,583 | 2 | Fandango | false | false |
| 28 | 33 | No Country for Old Men | $11,134 | -26.7% | 5 | -5 | $2,226 | $8,913,593 | 9 | Universal Pictures International (UPI) | false | false |
| 29 | 26 | My Blueberry Nights | $11,014 | -71.2% | 7 | -18 | $1,573 | $628,426 | 4 | BIM Distribuzione | false | false |
| 30 | 15 | The Spiderwick Chronicles | $10,435 | -90.8% | 30 | -62 | $347 | $3,391,805 | 5 | Universal Pictures International (UPI) | false | false |
| 31 | 39 | The Wind Blows Round | $9,978 | +45.8% | 6 | +3 | $1,663 | $578,442 | 51 | Aranciafilm | false | false |
| 32 | 30 | Into the Wild | $9,017 | -58.3% | 4 | -6 | $2,254 | $7,869,045 | 13 | BIM Distribuzione | false | false |
| 33 | - | Quiet Chaos | $7,390 | - | 7 | - | $1,055 | $8,335,009 | 11 | 01 Distribution | false | false |
| 34 | 36 | Jimmy della collina | $7,299 | -15.8% | 4 | - | $1,824 | $37,680 | 3 | Aranciafilm | false | false |
| 35 | 31 | Persepolis | $7,298 | -63.8% | 5 | -4 | $1,459 | $1,764,724 | 9 | BIM Distribuzione | false | false |
| 36 | 23 | The Water Horse | $5,874 | -88.8% | 26 | -55 | $225 | $1,942,871 | 6 | Sony Pictures Releasing | false | false |
| 37 | 12 | The Eye | $5,770 | -96.9% | 6 | -90 | $961 | $937,315 | 3 | Mediafilm | false | false |
| 38 | 32 | Gone Baby Gone | $5,688 | -67.4% | 4 | -1 | $1,422 | $92,731 | 3 | Walt Disney Pictures | false | false |
| 39 | 34 | Cover Boy... Last Revolution | $4,981 | -60.8% | 4 | -3 | $1,245 | $115,417 | 5 | Istituto Luce | false | false |
| 40 | 28 | Grande, grosso e... Verdone | $4,929 | -82.5% | 2 | -19 | $2,464 | $20,439,405 | 7 | Filmauro | false | false |
| 41 | 29 | Colpo d'occhio | $4,867 | -80.9% | 8 | -12 | $608 | $4,104,266 | 5 | 01 Distribution | false | false |
| 42 | 38 | Odette Toulemonde | $3,888 | -47.1% | 4 | -1 | $972 | $398,650 | 7 | Warner Bros. | false | false |
| 43 | 18 | 27 Dresses | $3,605 | -95.1% | 5 | -35 | $721 | $3,839,165 | 5 | 20th Century Fox International | false | false |
| 44 | - | Biùtiful cauntri | $3,155 | - | 3 | - | $1,051 | $125,770 | 7 | Lumière | false | false |
| 45 | 41 | The Early Bird Catches the Worm | $3,134 | -46.6% | 3 | +2 | $1,044 | $1,450,946 | 8 | Medusa Distribuzione | false | false |
| 46 | 46 | Andres and me | $2,554 | -29.6% | 1 | - | $2,554 | $18,362 | 2 | N/A | false | false |
| 47 | 44 | L'aria del lago | $2,410 | -42.8% | 1 | -1 | $2,410 | $10,161 | 2 | Independent Films | false | false |
| 48 | 24 | Questa notte è ancora nostra | $2,239 | -94.7% | 3 | -43 | $746 | $5,029,608 | 5 | Walt Disney Pictures | false | false |
| 49 | 45 | Mr. Magorium's Wonder Emporium | $2,195 | -45.7% | 1 | - | $2,195 | $2,466,591 | 13 | Moviemax | false | false |
| 50 | - | Days and Clouds | $2,100 | - | 1 | - | $2,100 | $6,004,940 | 26 | Warner Bros. | false | false |
