| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Forgetting Sarah Marshall | $1,706,876 | - | 255 | - | $6,693 | $1,738,495 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | - | Street Kings | $1,445,614 | - | 222 | - | $6,511 | $1,446,665 | 1 | 20th Century Fox International | true | false |
| 3 | 1 | The Spiderwick Chronicles | $975,913 | +6.1% | 262 | -7 | $3,724 | $5,513,786 | 3 | Paramount Pictures International | false | false |
| 4 | 4 | Nim's Island | $928,735 | +19.1% | 196 | - | $4,738 | $3,468,773 | 3 | Universal Pictures International (UPI) | false | false |
| 5 | 6 | Horton Hears a Who! | $797,078 | +19.1% | 303 | - | $2,630 | $9,560,797 | 5 | 20th Century Fox International | false | false |
| 6 | 2 | Superhero Movie | $655,498 | -28.6% | 188 | - | $3,486 | $2,149,799 | 2 | Roadshow Films | false | false |
| 7 | 3 | Prom Night | $530,679 | -37.9% | 124 | +1 | $4,279 | $1,827,215 | 2 | Sony Pictures Releasing | false | false |
| 8 | 5 | Semi-Pro | $404,901 | -39.8% | 195 | -7 | $2,076 | $3,251,536 | 3 | Roadshow Films | false | false |
| 9 | 7 | Step Up 2: The Streets | $353,601 | -24.5% | 178 | -5 | $1,986 | $7,896,169 | 5 | Universal Pictures International (UPI) | false | false |
| 10 | - | Gone Baby Gone | $268,596 | - | 33 | - | $8,139 | $268,596 | 1 | Walt Disney Pictures | true | false |
| 11 | 9 | U2 3D | $206,487 | -24.7% | 23 | - | $8,977 | $617,238 | 2 | Roadshow Films | false | false |
| 12 | 10 | St. Trinian's | $184,551 | -32.4% | 162 | -45 | $1,139 | $2,356,124 | 4 | Sony Pictures Releasing | false | false |
| 13 | 8 | Never Back Down | $159,996 | -51.9% | 113 | -33 | $1,415 | $2,785,795 | 4 | Roadshow Films | false | false |
| 14 | 16 | Lars and the Real Girl | $139,162 | -2.7% | 27 | +10 | $5,154 | $523,219 | 3 | Rialto Distribution | false | false |
| 15 | - | The Painted Veil | $130,630 | - | 49 | - | $2,665 | $139,620 | - | Paramount Pictures International | - | false |
| 16 | 19 | Paris | $129,567 | +33.5% | 29 | - | $4,467 | $353,828 | 2 | Icon Film Distribution | false | false |
| 17 | 11 | The Other Boleyn Girl | $113,454 | -45.2% | 84 | -21 | $1,350 | $3,741,950 | 6 | Universal Pictures International (UPI) | false | false |
| 18 | 13 | Before the Devil Knows You're Dead | $110,350 | -35.1% | 39 | +4 | $2,829 | $1,133,226 | 5 | Hopscotch Films | false | false |
| 19 | 18 | The Black Balloon | $94,347 | -23% | 63 | -11 | $1,497 | $1,702,622 | 7 | Icon Film Distribution | false | false |
| 20 | 14 | Drillbit Taylor | $83,535 | -48.9% | 88 | -86 | $949 | $3,789,488 | 5 | Paramount Pictures International | false | false |
| 21 | 12 | Vantage Point | $76,168 | -57.7% | 59 | -24 | $1,290 | $4,198,166 | 6 | Sony Pictures Releasing | false | false |
| 22 | 17 | The Bucket List | $73,930 | -43.8% | 74 | -33 | $999 | $7,223,249 | 9 | Warner Bros. | false | false |
| 23 | 15 | How She Move | $69,375 | -54.7% | 95 | -5 | $730 | $303,347 | 2 | Paramount Pictures International | false | false |
| 24 | 22 | Brick Lane | $39,993 | -35.7% | 25 | - | $1,599 | $513,994 | 5 | Madman Entertainment | false | false |
| 25 | 21 | Be Kind Rewind | $38,919 | -40.4% | 27 | -9 | $1,441 | $808,715 | 5 | Roadshow Films | false | false |
| 26 | 30 | Hannah Montana and Miley Cyrus: Best of Both Worlds Concert | $31,454 | +35.4% | 20 | - | $1,572 | $1,119,425 | 5 | Walt Disney Pictures | false | false |
| 27 | 23 | U Me Aur Hum | $29,518 | -47.1% | 8 | - | $3,689 | $107,529 | 2 | Eros Worldwide | false | false |
| 28 | 25 | The Kite Runner | $27,349 | -25.8% | 22 | -8 | $1,243 | $2,696,358 | 14 | Paramount Pictures International | false | false |
| 29 | 20 | 10,000 BC | $26,406 | -59.6% | 35 | -27 | $754 | $6,080,952 | 7 | Warner Bros. | false | false |
| 30 | 24 | No Country for Old Men | $21,099 | -51.4% | 31 | -10 | $680 | $5,835,716 | 17 | Paramount Pictures International | false | false |
| 31 | 34 | The Diving Bell and the Butterfly | $19,192 | +2.7% | 20 | -6 | $959 | $994,798 | 10 | Icon Film Distribution | false | false |
| 32 | 29 | In the Valley of Elah | $18,447 | -23.5% | 15 | +1 | $1,229 | $519,184 | 8 | Hoyts Distribution | false | false |
| 33 | 26 | The Secret of the Grain | $18,078 | -47.6% | 12 | -2 | $1,506 | $324,139 | 5 | Palace Films | false | false |
| 34 | 33 | Juno | $17,956 | -10.3% | 32 | -4 | $561 | $10,925,735 | 14 | 20th Century Fox International | false | false |
| 35 | 28 | There Will Be Blood | $12,330 | -49.1% | 20 | -14 | $616 | $2,400,045 | 11 | Walt Disney Pictures | false | false |
| 36 | 38 | Closing the Ring | $10,099 | -1.1% | 18 | -3 | $561 | $314,263 | 7 | Hopscotch Films | false | false |
| 37 | 32 | Krazzy 4 | $8,096 | -61.1% | 5 | - | $1,619 | $36,319 | 2 | Eros Worldwide | false | false |
| 38 | 37 | Hey Hey It's Esther Blueburger | $7,941 | -44.4% | 15 | -38 | $529 | $780,730 | 5 | Walt Disney Pictures | false | false |
| 39 | 36 | L'invité | $7,010 | -51.5% | 8 | -7 | $876 | $266,173 | 5 | Dendy Films | false | false |
| 40 | 27 | The Eye | $6,692 | -74.3% | 7 | -21 | $956 | $1,412,165 | 6 | Paramount Pictures International | false | false |
| 41 | 35 | In the Shadow of the Moon | $6,038 | -64.9% | 11 | -7 | $548 | $343,653 | 7 | Madman Entertainment | false | false |
| 42 | 44 | Global Haywire | $4,644 | -14.6% | 4 | +1 | $1,161 | $15,730 | 2 | Hopscotch Films | false | false |
| 43 | 42 | Lust, Caution | $4,089 | -45.8% | 7 | +1 | $584 | $797,302 | 14 | Universal Pictures International (UPI) | false | false |
| 44 | 43 | Bella | $3,069 | -52.2% | 4 | -5 | $767 | $192,090 | 9 | Hopscotch Films | false | false |
| 45 | 50 | Two Days in Paris | $2,321 | +64.3% | 6 | +3 | $386 | $1,694,710 | 17 | Hopscotch Films | false | false |
| 46 | 40 | Sweeney Todd: The Demon Barber of Fleet Street | $2,215 | -72.2% | 9 | -6 | $246 | $5,132,480 | 13 | Warner Bros. | false | false |
| 47 | 49 | Paranoid Park | $2,024 | +2.6% | 1 | -1 | $2,024 | $56,532 | 7 | Madman Entertainment | false | false |
| 48 | 48 | Death Defying Acts | $1,813 | -46.5% | 4 | -3 | $453 | $655,731 | 6 | Dendy Films | false | false |
| 49 | 54 | Rendition | $1,732 | +421.7% | 4 | - | $433 | $436,182 | 10 | Roadshow Films | false | false |
| 50 | 52 | August Rush | $987 | +35.4% | 3 | - | $329 | $637,802 | 9 | Magna Pacific | false | false |
| 51 | - | The King of Kong: A Fistful of Quarters | $353 | - | 1 | - | $353 | $96,628 | 8 | Dendy Films | false | false |
| 52 | 45 | Race | $173 | -96.2% | 1 | -5 | $173 | $330,599 | 5 | MG Distribution | false | false |
