| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | 10,000 BC | $492,451 | - | 51 | - | $9,655 | $492,451 | 1 | Warner Bros. | true | false |
| 2 | - | No Country for Old Men | $227,186 | - | 40 | - | $5,679 | $227,186 | 1 | Walt Disney Pictures | true | false |
| 3 | 2 | The Bucket List | $122,685 | -27.8% | 56 | -6 | $2,190 | $1,390,432 | 5 | Warner Bros. | false | false |
| 4 | 1 | The Game Plan | $111,664 | -49.9% | 48 | +1 | $2,326 | $1,089,790 | 4 | Walt Disney Pictures | false | false |
| 5 | 3 | Vantage Point | $68,669 | -55.3% | 46 | - | $1,492 | $264,143 | 2 | Sony Pictures Releasing | false | false |
| 6 | - | Death at a Funeral | $63,411 | - | 14 | - | $4,529 | $63,411 | 1 | - | true | false |
| 7 | 6 | P.S. I Love You | $55,882 | -41.1% | 28 | - | $1,995 | $181,788 | 2 | Alfa Films | false | false |
| 8 | 4 | There Will Be Blood | $50,277 | -57.6% | 35 | -1 | $1,436 | $396,639 | 3 | Walt Disney Pictures | false | false |
| 9 | 11 | Juno | $46,981 | -27.9% | 35 | +7 | $1,342 | $376,973 | 4 | Alfa Films | false | false |
| 10 | 8 | The Eye | $38,250 | -49.9% | 21 | -3 | $1,821 | $137,437 | 2 | United International Pictures | false | false |
| 11 | 5 | 3:10 to Yuma | $37,454 | -61.2% | 32 | - | $1,170 | $165,832 | 2 | Distribution Company | false | false |
| 12 | 7 | Sweeney Todd: The Demon Barber of Fleet Street | $34,956 | -56.9% | 43 | - | $812 | $605,309 | 4 | Warner Bros. | false | false |
| 13 | 12 | The Water Horse | $32,788 | -48.8% | 29 | -3 | $1,130 | $526,070 | 5 | Sony Pictures Releasing | false | false |
| 14 | 10 | Eastern Promises | $27,693 | -58.6% | 35 | -3 | $791 | $389,915 | 4 | Distribution Company | false | false |
| 15 | 19 | Love in the Time of Cholera | $18,961 | -31.9% | 27 | -4 | $702 | $545,628 | 8 | 20th Century Fox International | false | false |
| 16 | 13 | Cloverfield | $18,458 | -61.7% | 28 | -7 | $659 | $611,288 | 5 | United International Pictures | false | false |
| 17 | - | Martian Child | $17,567 | - | 20 | - | $878 | $17,567 | 1 | Distribution Company | true | false |
| 18 | 14 | Fool's Gold | $17,171 | -58.3% | 19 | -1 | $903 | $71,411 | 2 | Warner Bros. | false | false |
| 19 | 9 | Rambo | $16,912 | -75.9% | 25 | -22 | $676 | $284,181 | 3 | CDI Films | false | false |
| 20 | 17 | Atonement | $15,001 | -52.2% | 16 | -4 | $937 | $441,744 | 5 | United International Pictures | false | false |
| 21 | 15 | Explosive Brigade: Pirate Mission | $14,565 | -60.4% | 32 | -19 | $455 | $744,394 | 6 | Argentina Sono Film S.A.C.I. | false | false |
| 22 | 18 | An American Haunting | $13,017 | -55.8% | 28 | -6 | $464 | $504,257 | 6 | Distribution Company | false | false |
| 23 | 20 | Charlie Wilson's War | $11,236 | -41.5% | 19 | -14 | $591 | $831,274 | 7 | United International Pictures | false | false |
| 24 | 16 | Away from Her | $10,829 | -66.8% | 15 | -4 | $721 | $135,740 | 3 | Distribution Company | false | false |
| 25 | 23 | 27 Dresses | $7,444 | -37.6% | 23 | -2 | $323 | $279,698 | 5 | 20th Century Fox International | false | false |
| 26 | 57 | Sleuth | $5,089 | +6,968.1% | 10 | +9 | $508 | $162,238 | 9 | Sony Pictures Releasing | false | false |
| 27 | 25 | Alvin and the Chipmunks | $4,084 | -60.2% | 27 | -2 | $151 | $792,035 | 10 | 20th Century Fox International | false | false |
| 28 | 26 | Aliens vs. Predator: Requiem | $3,701 | -57.7% | 16 | -9 | $231 | $687,763 | 9 | 20th Century Fox International | false | false |
| 29 | 24 | Enchanted | $3,479 | -70.1% | 25 | -12 | $139 | $2,786,190 | 10 | Walt Disney Pictures | false | false |
| 30 | - | I Don't Want to Sleep Alone | $3,421 | - | 2 | - | $1,710 | $13,096 | 2 | 791 Cine | false | false |
| 31 | 27 | The Wayward Cloud 2007 Re-release | $3,416 | -51.5% | 2 | - | $1,708 | $13,078 | 2 | 791 Cine | false | false |
| 32 | 22 | National Treasure: Book of Secrets | $2,872 | -76.1% | 21 | -16 | $136 | $1,656,511 | 8 | Walt Disney Pictures | false | false |
| 33 | 35 | Gone Baby Gone | $2,645 | +115.9% | 6 | - | $440 | $421,205 | 16 | Walt Disney Pictures | false | false |
| 34 | 45 | Possible Lives | $2,189 | +357% | 5 | +3 | $437 | $14,105 | 5 | Primer Plano Film Group | false | false |
| 35 | 28 | Hitman | $1,699 | -58.6% | 12 | -3 | $141 | $180,071 | 7 | 20th Century Fox International | false | false |
| 36 | 21 | Hannibal Rising | $1,693 | -89% | 6 | -12 | $282 | $75,434 | 3 | United International Pictures | false | false |
| 37 | 30 | 1408 | $1,393 | -53.6% | 4 | -4 | $348 | $231,652 | 7 | United International Pictures | false | false |
| 38 | 29 | I Could Never Be Your Woman | $1,366 | -63.4% | 6 | -3 | $227 | $300,316 | 10 | CDI Films | false | false |
| 39 | 34 | Bridge to Terabithia | $859 | -39.1% | 3 | -2 | $286 | $99,046 | 9 | United International Pictures | false | false |
| 40 | 37 | La Vie En Rose | $824 | -29.4% | 2 | - | $412 | $497,426 | 44 | Alfa Films | false | false |
| 41 | 41 | American Gangster | $697 | -22.2% | 5 | -1 | $139 | $762,485 | 10 | United International Pictures | false | false |
| 42 | 39 | The Cave of the Yellow Dog 2008 Re-release | $602 | -39.5% | 2 | - | $301 | $29,257 | 6 | IFA | false | false |
| 43 | 36 | I Am Legend | $534 | -56.4% | 6 | -3 | $89 | $2,078,026 | 11 | Warner Bros. | false | false |
| 44 | 40 | The Golden Compass | $518 | -47.5% | 4 | +2 | $129 | $1,385,939 | 13 | Distribution Company | false | false |
| 45 | 44 | Michael Clayton | $421 | -19.3% | 2 | - | $210 | $575,533 | 22 | Alfa Films | false | false |
| 46 | 49 | Giants of Valdes | $303 | -10.9% | 2 | - | $151 | $82,166 | 8 | Primer Plano Film Group | false | false |
| 47 | 48 | Bee Movie | $253 | -31.6% | 3 | - | $84 | $1,468,357 | 14 | United International Pictures | false | false |
| 48 | - | Alpha Dog | $252 | - | 1 | - | $252 | $241,629 | 23 | Pachamama Cine | false | false |
| 49 | 46 | My Best Friend | $209 | -54.3% | 2 | - | $104 | $124,011 | 10 | Alfa Films | false | false |
| 50 | - | The Flock | $191 | - | 1 | - | $191 | $187,463 | 14 | CDI Films | false | false |
| 51 | 38 | The Heartbreak Kid | $163 | -84.6% | 2 | -3 | $81 | $913,008 | 18 | United International Pictures | false | false |
| 52 | 32 | Tres minutos | $133 | -92.5% | 2 | -3 | $66 | $6,237 | 3 | Primer Plano Film Group | false | false |
| 53 | 42 | 4 Months, 3 Weeks and 2 Days | $132 | -81.6% | 1 | -2 | $132 | $203,509 | 14 | Pachamama Cine | false | false |
| 54 | 55 | Encarnacion | $121 | -11.7% | 1 | - | $121 | $41,354 | 22 | Distribution Company | false | false |
| 55 | 43 | Beowulf | $118 | -79.4% | 2 | +1 | $59 | $705,703 | 16 | Warner Bros. | false | false |
| 56 | 56 | Underdog | $73 | -41.1% | 2 | -1 | $36 | $849,393 | 23 | Walt Disney Pictures | false | false |
| 57 | 51 | After the Wedding | $61 | -79% | 2 | - | $30 | $107,601 | 16 | Alfa Films | false | false |
| 58 | 53 | Lights in the Dusk | $50 | -69.7% | 1 | - | $50 | $52,423 | 24 | Alfa Films | false | false |
| 59 | 31 | Bratz | $49 | -97.7% | 2 | -3 | $24 | $43,644 | 4 | Pachamama Cine | false | false |
| 60 | - | Whisper | $38 | - | 1 | - | $38 | $111,658 | 15 | Alfa Films | false | false |
| 61 | 33 | I Do: How to Get Married and Stay Single | $25 | -98.4% | 1 | -2 | $25 | $70,627 | 7 | Alfa Films | false | false |
| 62 | 58 | At Five in the Afternoon | $15 | -67.4% | 1 | - | $15 | $16,114 | 15 | 791 Cine | false | false |
