| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | 27 Dresses | $145,596 | -26% | 51 | +1 | $2,854 | $412,441 | 2 | NuMetro Distribution | false | false |
| 2 | - | Cloverfield | $94,720 | - | 61 | - | $1,552 | $94,720 | 1 | United International Pictures | true | false |
| 3 | 2 | National Treasure: Book of Secrets | $90,094 | -19.3% | 82 | -3 | $1,098 | $1,223,289 | 5 | Ster-Kinekor Pictures | false | false |
| 4 | 3 | The Bucket List | $71,376 | -15.4% | 40 | - | $1,784 | $379,267 | 3 | NuMetro Distribution | false | false |
| 5 | - | Meet the Spartans | $59,410 | - | 30 | - | $1,980 | $59,410 | 1 | NuMetro Distribution | true | false |
| 6 | 4 | Atonement | $58,753 | -2.6% | 18 | - | $3,264 | $153,262 | 2 | United International Pictures | false | false |
| 7 | - | 1408 | $52,765 | - | 30 | - | $1,758 | $52,765 | 1 | Ster-Kinekor Pictures | true | false |
| 8 | 5 | I Am Legend | $41,747 | -30% | 60 | -2 | $695 | $1,765,923 | 7 | NuMetro Distribution | false | false |
| 9 | 6 | Good Luck Chuck | $40,265 | -24.4% | 30 | -1 | $1,342 | $255,759 | 3 | United International Pictures | false | false |
| 10 | 7 | Alvin and the Chipmunks | $33,097 | -18.8% | 43 | -5 | $769 | $900,149 | 7 | NuMetro Distribution | false | false |
| 11 | 12 | Hannah Montana and Miley Cyrus: Best of Both Worlds Concert | $16,764 | -30.3% | 3 | - | $5,588 | $43,208 | 2 | Walt Disney Pictures | false | false |
| 12 | 8 | Saw IV | $16,331 | -53.6% | 32 | -7 | $510 | $260,803 | 4 | Ster-Kinekor Pictures | false | false |
| 13 | 11 | Arthur and the Invisibles | $14,928 | -37.9% | 22 | -8 | $678 | $84,907 | 3 | Ster-Kinekor Pictures | false | false |
| 14 | - | Charlie Bartlett | $13,690 | - | 20 | - | $684 | $13,690 | 1 | NuMetro Distribution | true | false |
| 15 | 9 | Enchanted | $13,300 | -51.2% | 26 | -22 | $511 | $1,350,585 | 8 | Ster-Kinekor Pictures | false | false |
| 16 | 13 | Elizabeth: The Golden Age | $11,469 | -43.6% | 18 | -9 | $637 | $180,305 | 4 | United International Pictures | false | false |
| 17 | 16 | Into the Wild | $9,955 | -11.6% | 10 | - | $995 | $48,995 | 3 | United International Pictures | false | false |
| 18 | 19 | August Rush | $9,813 | +7.3% | 13 | +1 | $754 | $271,609 | 7 | NuMetro Distribution | false | false |
| 19 | 20 | The Jane Austen Book Club | $8,219 | +19.1% | 12 | +2 | $684 | $172,702 | 6 | Ster-Kinekor Pictures | false | false |
| 20 | 18 | Aliens vs. Predator: Requiem | $7,017 | -24.1% | 17 | - | $412 | $264,562 | 6 | NuMetro Distribution | false | false |
| 21 | 14 | We Own the Night | $6,340 | -53.5% | 13 | -12 | $487 | $463,709 | 6 | United International Pictures | false | false |
| 22 | 21 | American Gangster | $6,180 | -8.1% | 10 | -2 | $618 | $785,943 | 10 | United International Pictures | false | false |
| 23 | 23 | This Christmas | $3,023 | -39.2% | 6 | -3 | $503 | $179,127 | 8 | Ster-Kinekor Pictures | false | false |
| 24 | 25 | 30 Days of Night | $2,126 | +66% | 3 | - | $708 | $273,262 | 9 | United International Pictures | false | false |
| 25 | 10 | Talk to Me | $1,700 | -93.3% | 6 | -20 | $283 | $45,522 | 3 | United International Pictures | false | false |
